凋亡小體 的英文怎麼說
中文拼音 [diāowángxiǎotǐ]
凋亡小體
英文
apoptosis body-
( 2 ) the mortality of cp cell in 10 were increasing directly related with the time in the low temperature. after 120d some cp cells died in the way of apoptosis. most nucleus of cells were condensed, and chromosome was marginated beside the nucleus inner membrane, cell sizes were reduced, dna ladder showed in dna gel electrophoresis
（ 2 ） cp細胞系在10低溫下細胞死亡率與時間成正比， 120d的細胞具典型的凋亡現象，即細胞核固縮、染色體邊集在核膜內側；細胞體積變小；瓊脂糖凝膠電泳上顯示特徵性的「梯狀」帶。Part 1 : identification of a novel gene, tsarg2, and its sequence character cloning new apoptosis - related novel gene is a key to further understanding of apoptosis mechanism and the biological process of germ cell, and it is of momentous significance on clarifying physiology and pathology process of spermatogenesis. to rapidly attain human novel gene full - length cdna sequence, the gene - specific primers and the vector - specific primers have been designed for successful performing nested pcr and draft human genome searching to rapidly identify the tsarg2 ( genebank accession number ay040204 ) 5 " end from a human testis cdna library by using a cdna fragment ( genebank accession number be644542 ) as a electronic probe, which was significantly changed in cryptorchidism and represents a novel gene. furthermore, a mouse homologue of this gene was identified ( genebank accession number af395083 ) by lab on - line
本研究分為三個部分，其主要實驗方法及實驗結果如下：第一章tsarg2基因的克隆與序列分析從已獲得的在隱睪和正常睪丸對照中表達量有明顯差異的est片段（ be644542 ）入手，設計了基因特異性引物和載體特異性引物進行巢式pcr擴增，結合人類基因組草圖搜索法，從睪丸cdna文庫中快速分離出人類睪丸凋亡相關基因的5末端而獲得全長cdna ， genbank登錄號為ay040204 ，同時應用生物信息學的方法克隆了該基因在小鼠中的同源基因， genbank登錄號為af395083 。The mechanisms of such treatment have been proposed as inhibition of proliferation and angiogenesis, as well as induction of differentiation and apoptosis, as has been tested by various in vivo and in vitro experiments. in our experiments, it has also been demonstrated that after the treatment of arsenic trioxide, the k562 cells has undergone major morphological changes, which included nuclear shrinkage, membrane bleb and scattered apoptotic bodies. dna gel electrophoresis also discovered that the typical " dna ladder " phenomena in the treatment group, while the control group showed the regular genomic banding
我們在實驗中觀察到as _ 2o _ 3作用人紅白血病k562細胞后，細胞生長明顯變緩，部分細胞出現皺縮、染色質濃聚及胞膜起泡現象，部分細胞胞膜破裂，在其周圍有緻密的凋亡小體出現， dna電泳出現典型的凋亡「梯狀」帶，提示as _ 2o _ 3能有效抑制k562細胞生長，誘導k562細胞凋亡。We also investigated the pathological changes of mouse liver, thymus and cerebrum cortex challenged by so2 inhalation by in vivo tests. we studied the apoptotic induction on mouse spleen cells and cytotoxicity of human embryo lung fibroblasts of so2 derivatives by in vitro tests. in vivo tests of sulfur dioxide inhalation showed : ( 1 ) effects on mouse lung of so2 challenge : we found no significant apoptotic changes induced by so2 inhalation but obvious pathological changes of lung with vacuolating of osmiophilic multilamellar bodies which maybe related with the decrease of surfacant and decrease of microvillus of type ii alveolar cells ; we also found thickening of part of basement lamina between type i alveolar cells and capillary endothelium cells which may inhibit the dispersion of oxygen and contribute to lung dysfunction
二氧化硫熏氣染毒的體內實驗結果表明，在本次實驗的濃度范圍內（ 56mg m ~ 3 、 112mg m ~ 3 、 168mg m ~ 3低、中、高三個濃度） ： （ 1 ）通過透射電鏡、 dna凝膠電泳分析和流式細胞分析發現二氧化硫吸入染毒一周對小鼠肺臟沒有明顯的凋亡誘導作用，但通過透射電鏡觀察發現二氧化硫可引起肺臟明顯的超微結構改變，引起型肺泡上皮細胞板層體空泡化，微絨毛減少，線粒體緻密化或腫脹變性；肺泡血管內皮細胞和型肺泡上皮細胞之間基膜增厚，使氧氣彌散功能出現障礙，從而降低肺功能。Under mirror obviously ; the cell apoptosis divides into the early stage, the intermediate stage, stage of formation of apoptosis body and the later period stage ( three issuses of four stges ), its ultrastructure is mainly observed the cellular form, the cytoblastema, the nucleus, the chromatin change, the special sign of cell apoptosis - apoptosis body
鏡下可見：細胞凋亡分為早期階段、中期階段、凋亡小體形成階段和晚期階段（ 3期4階段） ，其超徽結構主要可見到細胞形態、胞漿、胞核、染色質的變化，及細胞凋亡的特異性標志凋亡小體。The obtained recombinant - 5 - htr plasmid was tranfected into human liver cancer smmc - 7721 cells. all data suggested the expression of plncx - atr could condense cell nucleus and increase nuclear fluorescence intensity, effectively repress the telomerase activity, cell growth and cell proliferation, and induce cell apoptosis
反義重組質粒plncx - atr轉染人肝癌smmc - 7721細胞，結果發現plncx - atr的表達有效地封閉或抑制肝癌細胞的端粒酶活性，使細胞的生長和增殖受到抑制，細胞體積變小、核緻密、核熒光強度增強，且促進其凋亡。Fig. 1 the apoptotic cells in ca1 sector, chromatin condensed and stained blue, apoptotic bodies edhibited ( tunel method 1000 )
1 ca1區的凋亡細胞，染色質固縮藍染並有凋亡小體形成（ tunel法1000 ） 。0. 1 - 5. 0 mmol / l al can induce dna ladders in the root - tips ( treated for 8 h ) and suspension cells ( treated for 24 h ) of barley, but no apoptotic bodies were observed
0 . 1 - 5 . 0mmol / l鋁處理大麥根尖8h或懸浮細胞24h均產生了梯狀dna ，但未觀察到凋亡小體的形成。At the arrow is a rounded pink apoptotic body
箭頭示粉紅色的凋亡小體。分享友人