劑量依賴性 的英文怎麼說

中文拼音 [jìliángyīlàixìng]
劑量依賴性 英文
dose dependent
  • 劑 : Ⅰ名詞1 （藥劑; 制劑） a pharmaceutical or other chemical preparation 2 （某些有化學作用的物品） a...
  • 量 : 量動1. （度量） measure 2. （估量） estimate; size up
  • 依 : Ⅰ動詞1 （依靠; 依仗） depend on; rely on 2 （依從; 同意） comply with; listen to; yield to Ⅱ介詞...
  • 賴 : i 動詞1 （依靠） rely on; depend on 2 （逗留不肯離去） hang on in a place; drag out one s stay in...
  • 性 : Ⅰ名詞1 （性格） nature; character; disposition 2 （性能; 性質） property; quality 3 （性別） sex ...
  • 劑量 : [物理學] [醫學] dosage; dose; dosis劑量槽 dosage bunker; 劑量測定（法） dosimetry; health work; ...
  1. We immunize the balb / c mice with pc4. 0f and pc3. 1f by paunch and muscle administration and immunize each with different content of 10 g, 50 g 100 g. the antibodies in serum against newscastle disease virus f gene protein are tested by elisa. the result showes that two kinds of dna vaccines can induce specific antibody response to encoded proteins in 15 weeks by im and ip, but antibodies response is little different

    免疫結果顯示，採用2種免疫途徑（肌肉注射，腹腔注射） ， 3個劑量（ 10 g 、 50 g和100 g ）免疫balb c小鼠，在被檢測的15周內，肌肉注射和腹腔注射組均可產生抗體，抗體的產生有明顯的劑量依賴性， 50 g只和100 g只明顯優於10 g只，而100 g只與50 g只相似（肌肉注射）甚至稍低（腹腔注射） 。
  2. Our previous studies demonstrated that agmatine not only reduced the amplitude of action potential ( apa ), maximal rate of depolarization ( vmax ), velocity of diastolic ( phase 4 ) depolarization ( vdd ), and rate of pacemaker firing ( rpf ), but also prolonged 90 % duration of action potential ( apd90 ) in a concentration - dependent manner

    我們先前的實驗證明，胍了胺可劑量依賴性地抑制兔竇房結起搏細胞的0相最大上升速度（ v _ （ max ） ） ，動作電位幅度（ apa ）和舒張期除極化速度（ vdd ） ，起搏細胞放電頻率（ rpf ） ，而且能延長90動作電位時程（ apd _ （ 90 ） ） 。
  3. These findings suggest that candesartan has dosage - dependent, anti - inflammatory effects that are mediated by suppression of nf - b actiation and chemokine expression

    這些研究表明，坎地沙坦是劑量依賴性、抗炎作用是通過抑制nf - b的活性和趨化因子表達介導的。
  4. These findings suggest that candesartan has dosage - dependent, anti - inflammatory effects that are mediated by suppression of nf - b activation and chemokine expression

    這些研究表明，坎地沙坦是劑量依賴性、抗炎作用是通過抑制nf - b的活性和趨化因子表達介導的。
  5. The cumulus expansion, cumulus cells dna fragmentation, oocyte meiotic maturation and degeneration were determined 44 h after incubation. snp inhibited cumulus expansion and cumulus cells dna fragmentation in a dose - dependent manner

    結果發現， snp可劑量依賴性地抑制卵丘細胞的擴展和dna片段化，同時抑制ceos中卵母細胞的減數分裂恢復，抑制m向m期轉變。
  6. Studies of the crystal structure of endostatin have shown a compact globular fold, with one face particularly rich in arginine residues acting as a heparin - binding epitope, this site was recently shown to be involved in the inhibition of induced angiogenesis. experimental studies show that recombinant endostatin specifically inhibits the proliferation of endothelial cells in a dosedependent fashion. recombinant endostatin from bacteria is largely insoluble, but still efficient in arresting tu mor growth after injection into mice. intermittent therapy with recombinant bacterially produced endostatin reduces several experimental tumors, including lewis lung carcinoma, to a dormant state. no sign of drug induced resistance has been reported and, in the original study, the treatment dormancy appeared to persist even when therapy was discontinued. sowe regard endostatin as a promising anti - tumor drug

    許多研究表明重組內皮抑素特異性抑制內皮細胞增殖，而且這種抑制作用呈劑量依賴性。細菌表達產物內皮抑素大部分以不溶形式存在，將這種混懸液注射治療老鼠仍可以抑制腫瘤生長。于小鼠皮下重復注射內皮抑素重組蛋白，幾乎完全抑制鼠lewis肺癌等多種腫瘤生長，並無耐藥性產生，即使中斷治療腫瘤也不再復發。
  7. The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased

    結合以上創建的方法和免疫熒光流式細胞術，用k562細胞株可溶性分泌物（上清）對外周血單個核細胞（ pbmc ）進行培養以模擬體內微環境，然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究，結果發現用腫瘤上清培養的pbmc細胞數量下降明顯，但同時對其有激活作用，且呈劑量依賴性；細胞數的下降主要是由細胞壞死和凋亡引起的，腫瘤上清對細胞周期沒有阻斷作用，反而略有促進作用； t細胞亞群比例增加，並促進表達th1 、 th2細胞因子。
  8. Abstract : yuanhua dose dependently increased the resting tension and the mean contractile amplitude of isolated bladder detrusor muscle strips in guinea pigs. the effect was blacked by verapamil partly

    文摘:芫花可劑量依賴性增高豚鼠膀胱逼尿肌肌條的張力，增大膀胱逼尿肌肌條的收縮波平均振幅。異搏定可部分阻斷芫花增高膀胱肌條張力的作用。
  9. Materials and methods in our study, first the e. coli bl21 transformed already are cultivated in smaller scale and then the plasmids dna were extracted by the methods of alkaline lysis. the plasmids dna extraction were processed 37 overnight by the restrictive endo - incisase bam h i and xho i. the incision products were used to check the integrality and variability of the recombinant plasmids dna by 1 % agarose gel elec - trophoresis

    同預想結果基本吻合，大規模培養后純化得到的融合蛋白通過sds page顯示在52kda處有一條帶，而酶切后產物電泳結果顯示在26kda處分另有兩條蛋白帶，其中一條為gst ，另一條為hbrp ，基本符合實驗結果； hbrp對tpk活性的抑制呈劑量依賴性。
  10. 3. calcitonin gene - related peptide attenuates glutamate - induced inhibition of pulmonary surfactant lipid synthesis ( d cgrp could reverse the decrease of [ 3h ] - choline incorporation induced by glu with dose - dependence ; ( 2 ) cgrp could block the decrease of the content of cct a mrna induced by glu in lung tissue ; ( 3 } cgrp could reduce the impairment of the ultrastructure of at ii cells induced by glu ; ( 4 ) cgrp could reverse the increase of mda content and decrease of sod level induced by glu in cultured lung explants, respectively ; ? grp had no significant effect on nos activity and increase of no production induced by glu

    降鈣素基因相關肽減輕谷氨酸所致肺表面活性物質脂質合成抑制的保護作用降鈣素基因相關肽grp ）可顯著減輕0所致肺組織h一膽堿摻入pc量的降低，並且呈劑量依賴保護效應； cgrp可逆轉gill所致cctqinrna含量的降低； cgrp可減輕o所致肺11上皮細胞超微結構的損傷； cgrp可逆轉o所致肺組織勻漿中mda含量增多、 sod水平降低的效應，並可逆轉q所致肺組織ldh釋放增多的效應； cg販對gill引起的nos活性和no含量的升高均沒有顯著性影響。
  11. The results were as follows : ( l ) the pre - incubation of pmr induced the exocytosis of the cortical granules ( cgs ) in the oocytes and reduced the quantity of the microvillus on the surface of oocytes ; ( 2 ) the matrix of cg might migrate to the surface of plasma membrane of oocytes after pmr pre - treatment. ( 3 ) incubation of zona - free hamster eggs with spermatozoa pretreated with pmr a ntiserum was associated with a dose - dependent significant reduction in the number of spermatozoa binding to the oolemma, compared with a contraband with a dose - dependent reduction of the fertilization rate and the penetration index. the results indicate that mr of human sperm plays an important role in sperm - oocyte fusion and oocyte activation

    結果顯示： （ 1 ）人精子mr能夠誘發去透明帶金黃地鼠卵母細胞中皮質顆粒的胞吐，並引起卵母細胞膜表面微絨毛形態和數量發生改變； （ 2 ）皮質顆粒胞吐后，其內容物可結合到卵膜表面； （ 3 ）抗mr抗血清預處理精子可抑制精子與卵子的結合與融合，使受精率、穿透指數和結合指數下降，並均有劑量依賴性。以上結果提示，人精子mr在受精過程中起重要作用，其主要作用可能是介導精-卵膜融合併促進卵母細胞的活化。
  12. The apoptosis induced by extract of russula subnigricans hongo was investigated in little white rat liver and kidney cells by agarose gel electrophoresis. the result showed that agarose gel electrophoresis of dna extracted from poisoned little white rat liver and kidney cells revealed typical 180 ~ 200bp integer - fold " ladder " " bands. apoptosis induced by extract of russula subnigricans hongo was dose - and time - dependentthe result indicated that extract of russula subnigricans hongo could induce apoptosis in little white rat liver and kidney cells

    4 .用電泳技術研究亞稀褶黑菇粗毒液誘導小白鼠肝腎細胞凋亡，小白鼠亞稀褶黑菇抽提液中毒后，肝腎細胞. dna經瓊脂糖凝膠電泳出現180一200bp整數倍的ona梯形帶， 19 . 09 / l一28 . 59 / l范圍內，亞稀褶黑菇提取液誘導肝腎細胞凋亡表現出時間和劑量依賴性
  13. As with the breast cancer study, the dose - response data on a total of 1, 448 individuals were put into order by serum 25 ( oh ) d level and then divided into five equal groups, from the lowest blood levels to the highest

    和乳腺癌研究一樣，對總數1448的個體劑量依賴性數據根據血清中25 （ oh ） d水平進行排序，然後從最低血中濃度到最高血中濃度分成五個平均組。
  14. Using this system, we have studied matrine - inhibittory effect and trifluoperation - neuroprotection effect in hippocampal slices, also discussed the mechanism of long - term potentiation using anesthetic rats. the experiment results showed that matrine can inhibit the hyperactivity induced by penicillin sodium in dosage by changing the relative parameters of field potential ; trifluoperation can alter ps change with the time, enhance the degree and the ratio of ps recovery, then minis the hypoxic injury ; high frequency stimulate can increase ps amplitude and epsp slope for long time, buildup the in / out function of nerve cells, and enhance synaptic plasticity

    結果表明，苦參堿能夠劑量依賴性地抑制青霉素誘導的神經元順向信號傳導激活過程，使細胞外記錄到的場電位各個參數發生相應改變；三氟拉嗪可以改變ps的時相變化，提高ps的恢復程度和恢復率，減小了神經元因缺氧引起的不可逆損傷；高頻刺激（ highfrequencystimulate ， hfs ）可以長時間的增強ps的幅度和epsp的斜率，進而增強神經元的輸入輸出功能，增加了突觸的可塑性。
  15. Kyot2 lacked two lim domains from the c terminus and had a frameshift in the last exon, creating the rbp - j - binding region in the c terminus. kyotl had a negligible level of interaction with rbp - j. the binding site of kyot2 on rbp - j overlaps those of ramic and kyot2 repressed the rbp - j mediated transcriptional activation by ramic by competing with them for binding to rbp - j

    在肌肉母細胞系czc12內過表達kyoth時可阻斷轉錄激活物notch胞內區或ebnaz對rbp依賴性啟動子的轉錄激活作用，這種阻斷作用呈劑量依賴性，提示kyoth可與notch胞內區或ebnaz競爭rbp j上的結合位點，從而抑制二者的轉錄激活活性
  16. The originalities of this paper are : 1, development of a a flow cytometry - based assay for quantitative analysis of cellular proliferation and cytotoxicity in vitro ; 2, the soluble secretion of k. 562 cell lines reduce the number of pbmc, but promote the activity of pbmc in dose - dependent manner ; 3, soluble secretion of k562 cell lines can induce the no production by pbmc, but no only plays a part of the role of soluble secretion of k562 cell lines ; 4, establishing a in vitro model and giving some parameters for sreening and appraising anti - tumor medicine

    本研究的創新點在於： l 、建立了用流式細胞術定量測定細胞增殖和細胞毒性的直接檢測技術； 2發現k562可溶性分泌物劑量依賴性地使pbmc細胞數量減少但活性增加； 3 、 k562可溶性分泌物能誘導pbmc產生no ，但是no的作用並不等同於腫瘤上清的全部作用。 4 、為抗腫瘤藥物篩選提供了一個體外模型，並明確了一些篩選指標。
  17. Hwtx - v can reversibly paralyze locusts and cockroaches for several hours with an ed50 value as 16 + 5ug / g to locusts, and larger dose of the toxin can cause death. the neurotoxic symptoms induced by intra - abdominal injection of huwentoxin - v were paralysis, immobilization and last gradually recovery

    Hwtx -通過腹腔注射，能使蝗蟲和蜚蠊產生可逆的劑量依賴性的麻痹作用，麻痹時間長達十多個小時，在高劑量（ 100 g g ）時可使蝗蟲和蜚蠊致死，對蝗蟲的ed _ （ 50 ） = 16 5 g g 。
  18. The fracture risk is dose dependent and occurs rapidly after the start of treatment

    這種骨折是劑量依賴性的，並且在治療開始后很快發生。
  19. Inhibitory effects of total saponins of panax notoginseng on cardiac hypertrophy induced by pressure overload in rats : dependent effect of medical dosage

    大鼠壓力超負荷性心肌肥大與三七總皂甙的干預效果藥物劑量依賴效應
  20. Conclusion : 1 ) il - 12 is able to induce apoptosis in t cells by a dose and time depent manner

    結論： l 、 il 12可誘導t細胞凋亡。誘導凋亡效應呈時間和劑量依賴性。
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