劑量效應研究 的英文怎麼說

中文拼音 [jìliángxiàoyīngyánjiū]
劑量效應研究 英文
dose response studies
  • 劑 : Ⅰ名詞1 （藥劑; 制劑） a pharmaceutical or other chemical preparation 2 （某些有化學作用的物品） a...
  • 量 : 量動1. （度量） measure 2. （估量） estimate; size up
  • 效 : Ⅰ名詞（效果; 功用） effect; efficiency; result Ⅱ動詞1 （仿效） imitate; follow the example of 2 ...
  • 應 : 應動詞1 （回答） answer; respond to; echo 2 （滿足要求） comply with; grant 3 （順應; 適應） suit...
  • 研 : 研同 「硯」
  • 究 : Ⅰ動詞（仔細推求; 追查） study carefully; go into; investigate Ⅱ副詞[書面語] （到底; 究竟） actually; really; after all
  • 劑量 : [物理學] [醫學] dosage; dose; dosis劑量槽 dosage bunker; 劑量測定（法） dosimetry; health work; ...
  • 效應 : [物理學] effect; action; influence
  • 研究 : 1. （探求） study; research 2. （考慮或商討） consider; discuss; deliberate
  1. In outpatient service of epileptic specialized subject, what secure relatively is have masterly the doctor that treats a technology, have unified diagnostic level, can have thorough analysis and research to diagnose and be being treated, hand - in - hand travel periodic is followed visit observation ; can the specific characteristic according to patient ' s condition of a certain patient, make individual change, the plan of diagnosis and treatment that has specific aim, build corresponding card, anamnesis and observation form to wait, for epileptic cure research was offerred convenient ; conduct propaganda concerns epileptic basic knowledge, reach birth arrangement to the patient ' s life, job, study, marriage, offer rationalize proposal ; make the patient ' s diagnosis, anthology medicine, dosage, usage, side - effect, curative effect, accompany behavior of disease, intellectual growth, spirit, mentation to wait to lie under close observation of the doctor

    在癲癇專科門診，有相對固定的具有精湛治療技術的醫生，有統一的診斷標準，能對診斷和治療進行深入的分析和研究，並進行定期的隨訪觀察；能根據某個病人病情的具體特點，制定個體化、有針對性的診療計劃，建立相應的卡片、病歷及觀察表格等，為癲癇的治療研究提供了方便；宣傳有關癲癇的基本知識，對病人的生活、工作、學習、婚姻及生育安排，提供合理化建議；使病人的診斷、選藥、劑量、用法、副作用、療效、伴隨疾病、智力發育、精神行為、心理狀態等都處在醫生的嚴密觀察之下。
  2. The results of research on the workability of hbc concrete show that hbc concrete, when compared with opc concrete, has excellent compatibility with superplasticizer, in terms of better initial fluidity, less slump loss, definite saturation point and less dosage at saturation point. in addition, good mineral admixture such as i class fly ash can obviously improve the workability of hbc concrete. moreover, hbc concrete exhibits more excellent workability under the condition of low w / c ratio, which indicates hbc is more suitable for making super high strength concrete whose w / c ratio is very low

    對高貝利特水泥高性能混凝土工作性能的研究結果表明，高貝利特水泥與高效減水劑具有良好的適應性，表現為初始流動度較大，經時損失較小，具有明顯的飽和點且飽和點摻量較小；此外，優質的礦物摻和料如一級粉煤灰能明顯改善hbc混凝土的工作性能；更為突出的是hbc混凝土在低水膠比的情況下表現出更為優異的工作性，這一特性預示著高貝利特水泥更適宜配製水膠比很低的超高強混凝土。
  3. In this thesis, the development of emulsion polymerization theory and related new technologies are comprehensively reviewed, and the synthetic technologies of acrylate latex modified by organosilicon both at home and abroad are also reviewed. based on the current development and research in this field, attentions of this study are focused on three ways for preparing novel acrylate latexes modified by organosilicons, that is, 1 ) the acrylate monomers are copolymerized with unsaturated silicons by emulsion copolymerization ; 2 ) a new latex with microphase separation morphology is synthesized, which shows a core - shell structure character ; 3 ) soap - free polymerization is explored for preparing a higher - performance latex using an unsaturated silicon monomer, different acrylates and a reactive emulsifier. by using techniques of delaying addition of organosilicon monomer and a hydrolysis inhibitor, the hydrolysis and condensation of 3 - ( trimethoxysilyl ) propyl methacrylate during polymerization can be effectively prevented, as a result, organosilicon content in the macromolecular chain is increased

    同時採用有機硅單體延遲滴加及添加水解抑制劑等技術，有效防止了-甲基丙烯酰氧基丙基三甲氧基硅烷在乳液聚合過程中的過渡水解及縮合反應，提高了聚合物大分子鏈中有機硅鏈節的含量；利用紅外光譜與差示掃描量熱儀對產物分子結構進行了表徵，並通過對共聚產物力學和吸水率的測試，證實了本研究所制備的有機硅改性丙烯酸酯共聚物具有比純丙烯酸酯聚合物更優良的力學及耐水性能；從分子設計角度出發，利用醇解反應合成出水解、縮合反應速率較慢的兩種新型不飽和有機硅單體： ?甲基丙烯酰氧基丙基三乙氧基硅烷和?甲基丙烯酰氧基丙基三異丙氧基硅烷；利用核磁共振對新型硅烷單體結構進行了證實；研究表明利用新型硅烷單體可以制備出高硅烷含量的有機硅改性丙烯酸酯乳液，且其聚合產物具有較高的力學及耐水性能。
  4. The tested inhibitors are listed as follows : alkali matter including lime, silicon - containing fertilizer and coal ash ; organic matter including plant compost, pig manure and humic acid ( ha ) ; ion inhibitor such as znso4 pot experiment, in which lettuce ( lacruca sativa var. augustana irish ) was chosen as the tested plant, involved 27 treatments, 4 replications each

    本研究選用的調控劑有堿性物質石灰、硅肥、粉煤灰，有機物料秸稈堆肥、豬糞、胡敏酸，離子拮抗劑znso _ 4 。按不同類型調控劑的比較、有機物料與石灰的組合效應、石灰不同用量的比較等原則設計試驗。
  5. This study examined the effects of long - term ( 14 mo ) administration of ultrahigh dosages of the angiotensin receptor blocker candesartan on the progression of renal injury in spontaneously hypertensie rats ( shr )

    該研究調查了超高劑量的血管緊張素受體阻滯劑坎地沙坦對自發性高血壓大鼠的腎損傷進展的長期效應（ 14個月） 。
  6. This study examined the effects of long - term ( 14 mo ) administration of ultrahigh dosages of the angiotensin receptor blocker candesartan on the progression of renal injury in spontaneously hypertensive rats ( shr )

    該研究調查了超高劑量的血管緊張素受體阻滯劑坎地沙坦對自發性高血壓大鼠的腎損傷進展的長期效應（ 14個月） 。
  7. In practical uses, the major performances of concrete are associated with the quantities, types and the service conditions of the expansion - admixture. the expansion admixtures of concrete available at present still have many shortcomings, such as the greater quantities required, the non - relevance between developments of concrete strength and durability and expanding speeds of expansion admixture, the evaluation of expanding effects, the def of aft etc. unfortunately, few achievements in these aspects have been obtained all over the world

    在實際使用中，膨脹劑類型、摻量及其使用條件對混凝土的主要性能影響很大，現有的膨脹劑存在著實際摻量較大、混凝土強度及耐久性發展與膨脹劑的膨脹速率不協調、膨脹效能如何評價、鈣礬石aft相延遲性反應（ def ）等一系列問題，而目前國內外這方面的研究成果較少。
  8. It got firsthand information through a great deal of investigation and research, made omni - direction analysis and study on the yantai zhongya pharmaceutical company ( ytx found the key factor which caused the former depression. it goes from the current situation and future development trend, combining the situation and market character of this industry in the world, with the writer ' s long time and deep analysis upon those successful foreign enterprises in china. the paper puts forwards the strategy of promotion, product improvement, brand establishment hi marketing area, hi the respect of marketing channel and promotion, the paper described concept of credit management, customer management and the way of occupying final market

    本論文採取實證研究方法，將營銷管理理論與企業的經營運作相結合，通過大量的調查研究，掌握了第一手資料：對煙臺中亞藥業公司進行了全方位的分析研究，找出了前階段經營滑坡存在的問題；進而針對這些問題，從我國醫藥發展的現狀以及未來發展的趨勢著手，結合當前世界醫藥行業面臨的形勢和市場特點，再加上筆者多年來對國內成功的外企? ?醫藥公司加以深入的分析，提出了在產品市場營銷方面的市場拓展、產品劑型改進、樹立名牌產品等策略；在其銷售渠道與促銷方面提出了誠信管理、客戶管理以及如何占領終端市場，並闡述了煙臺中亞藥業公司從企業自身發展和應對競爭者挑戰應採取的行之有效的營銷策略及實施建議。
  9. This paper unfolds engineering disposition and theoretical research of negative temperature high performance concrete ( nthpc ) with the damage of many factors motivation, the project background based on qing - zang railway engineering, which is one of four - emphasized engineering during the tenth five - plan. due to the difference of environment of construction and service between nthpc and ordinary concrete, and therefore durability of nthpc is required to higher level. at a first, nthpc must avoid frozen damage at early age and possess anti - freezing property at later period, in order to meet engineering practicable application need, and this are two emphasized and difficult problems, as for nthpc ; by means of mechanism analysis about deicing - agent ingredient and anti - freezing at early period, adopting composite technique routine of mineral addition + anti - freezing element + water - reducer4 - air - entraining + anti - erosion of steel component etc, based on orthogonal experimental approach, fd - 1 composite functional admixtu re was manufactured, which has more property and orientation on qing - zang railway

    負溫混凝土由於和普通混凝土在施工環境及服役環境上存在的差異，因此表現為比普通混凝土更為較高的耐久性要求；負溫混凝土首先要避免早期的凍害以及具備長期抗凍性能，才能夠滿足工程實際應用的要求，這也是負溫混凝土必須解決的兩大技術關鍵；通過對目前常用防凍劑組分作用機理的分析研究及混凝土早期防凍機理探討，採用礦物外加劑+防凍組分+高效減水劑+引氣+阻銹組分功能復合的技術路線，通過正交試驗設計復配了適應青藏鐵路工程要求的專用多功能復合型外加劑fd - 1 ；並在此基礎上配製不同等級負溫高性能混凝土，開展一系列包括硫酸鹽侵蝕、氯離子滲透、抗凍融循環、收縮及耐磨性等耐久性能研究；通過對fd - 1組分和摻量的調整，優化負溫混凝土在施工特性、力學指標和耐久性三個方面的兼容、協調性。
  10. Abstract : based on the fundamental principle of hypothesis strain equivalence, itwas investigated a physical concept of high strength concrete at minus temperature ( hscmt ) freezing damage parameter, the elastic modulus of frost concrete with anti freeziug admixture and without antifreezing admixture built and it was analyzed their variate process and the condition adaptated. it is purpose to judge hscmt frost failure process

    文摘:從應變等效性假說的基本原理出發，研究了負溫混凝土凍結損傷參數? ?彈性模量法中受凍后測試的損傷混凝土彈性模量的物理概念，從而分析了摻防凍劑混凝土及不摻防凍劑混凝土受凍后的彈性模量變化過程及其選用該參數的適應性條件，為判斷負溫高強混凝土材料凍結失效過程提供保證。
  11. In the field of the phytoremediation of copper pollution, submerged macrophytes are focused less than the terrestrial plants. in this study, ceratophyllum demersum l. and cahomba caroliniana a. gray were used as the test plant. the following two aspects were investigated in vivo methods : 1 ) the toxicity effects of cu2 + on the three main antioxidant enzymes ( including cat, pod and sod ) of two submerged macrophytes were detected at different low doses and on the chronic exposure, in order to establish the dose - effect relationship and the time - effect relationship, and thereby acquire the toxicity threshold ; and 2 ) with two submerge macrophytes throng cultured individual or combined on the chronic exposure, it was found on the bcf of copper and the influence of interspecific relationships to the submerge macrophytes resistance or bioconcentration

    本論文以兩種大型沉水植物金魚藻（ c . demersuml . ）和水盾草（ c . carolinianaa . ）為受試植物，從它們對水體中cu ~ （ 2 + ）的生物富集作用和動態，以及cu ~ （ 2 + ）對它們體內抗氧化酶的急性毒性效應和亞急性毒性效應兩方面進行了研究： 1 ）通過體內暴露不同劑量的cu ~ （ 2 + ） ，探討cu ~ （ 2 + ）對植物體內三種主要的抗氧化物酶（ sod ， pod ， cat ）的毒理效應，建立劑量?效應關系和時間?效應關系，以揭示沉水植物對cu ~ （ 2 + ）的抗性機制； 2 ）通過對金魚藻，水盾草單獨培養和共同培養的方式，分別研究了兩種沉水植物對cu ~ （ 2 + ）的生物富集系數及其動態以及兩種植物的種間關系對富集銅和植物耐性的影響，綜合評價了兩種植物在銅污染水體的植物修復中的應用前景。
  12. Fluorescence in situ hybridization detection of chromosome translocations induced by 60co - rays in human lymphocytes dose - response curve and persistence

    射線誘發人外周血淋巴細胞染色體易位率劑量效應曲線及易位的持續性研究
  13. In order to verify the reliability and validity of the heavy ion irradiation simulation of neutron and proton irradiations, radiation damage and its thermal annealing behavior in a - al2o3 irradiated at the equivalent dose by 85 mev 19f ions and by en > 1 mev neutrons, respectively, are studied

    為驗證重離子模擬輻照的可行性，首先進行了等效劑量下的中子輻照與重離子輻照后- al _ 2o _ 3樣品中輻照損傷及其退火效應研究。
  14. Radiation effects have been investigated up to - 30 dpa by the heavy ion irradiation simulation and positron annihilation lifetime techniques in the home - made modified 316l stainless steel and the commercially available stainless steel and tungsten, which are used as the beam window materials for the spallation neutron source in accelerator driven radioactive clean nuclear power system ( ads ). their radiation resistance properties are compared

    本工作採用重離子輻照模擬和正電子湮沒壽命測量技術研究了加速器驅動潔凈能源系統（ ads ）散裂中子源束窗材料鎢、普通不銹鋼和國產改進型316l奧氏體不銹鋼在0 30dpa輻照劑量范圍的輻照效應，並對它們的抗輻照性能作了比較。
  15. In this paper, bioremediation technology of contaminated soil with organic pollutants was summarized, which were technologies of the microorganism remediation, the phytoremediation and the mycorrhiza remediation for contaminated soil, the future developments of these bioremidation technologies were prospected as follows : when the efficient surfactants was used to enhance phytoremediation systems, its optimum doses should be considered ; studying on the important role of the rhizosphere exudates in the phytoremediation, seeking the best matching partners between plant and microorganism and the best mycorrhizal funguses to improve pollution degradation

    摘要綜述了有機污染土壤生物修復的三種技術，即微生物修復技術、植物修復技術、菌根生物修復技術及其研究現狀，並展望了這三種生物修復技術今後的研究方向，如利用表面活性劑提高植物修復效率時，應考慮其最佳使用量；加強研究根分泌物在植物修復土壤污染中的作用；進行植物微生物聯合體篩選技術研究；篩選促進污染物降解的優良菌根菌種等。
  16. The article developed the self - compensation repairing lubrication additives which endowed with new function to old lubrication oils according to the theory of self - compensation repairing theory by aided financially from china nature science fund ( ratification number : 59975039 ). the first, the article studied the tribological effect of several kinds of lubrication additives by single - phase, two - phase and three - phase mixture by four - ball machine. the article studied the effect of the mixture ratio and the additive concentration on tribological effect - antifriction, wear - resisting and bearing capacity

    論文首先以四球法，對新合成的幾種潤滑添加劑的單相和雙相、三相復配后的摩擦學特性進行了較系統地研究，研究了復配比例和添加量等對其摩擦學性能?減摩、耐磨、承載性能的影響，在此基礎上優選了es12和esm122兩種潤滑添加劑，對其進行了較系統的磨損自補償修復效應及其摩擦學效應研究和對四種成品潤滑油的適應性研究，並對摩擦表面的自補償膜進行了紅外光譜分析。
  17. In conclusion, the results of checking of physiochemistry items, uv spectrum data, chromatographic fingerprints test and safty evaluation indicated that gpif avivity evaluation samples were eligible. through the comparison of methods for evaluating immunobiologic activity and the choosing of optimum methods to evaluating immunobiologic activity, we created assay methods evaluating immunobiologic activity for quality standard of gpif. the research of dose - effect of gpif can also supply theoretical materials for pharmacology. that the experiments on the factors which affect the immunobiologic activity of gpif and the comparison with similar drugs demonstrated that gpif was a kind of cellar immunoregulating drug with stable and high immunobiologic activity

    綜上所述，通過對gpif免疫生物活性評價實驗樣品材料的準備，顯示由該工藝制備的實驗樣品材料理化性質穩定，活性成分含量充足，安全可靠，可以用來作為gpif免疫生物活性的評價;通過對gpif免疫生物活性評價方法的比較篩選及評價方法的優化，為gpif質量標準建立了較優免疫生物活性評價手段;同時gpif免疫生物活性劑量效應的發現，為該產品的免疫生物活性深入研究奠定了基礎，也為gpif藥效學研究提供了理論資料;對gpif免疫生物活性影響因素的探討及與同類藥品免疫生物活性的對比，證實gpif是一種免疫生物活性穩定、且具有高免疫生物活性的細胞免疫增強劑;同時，本研究也為同類產品免疫生物活性評價提供了方法學參考。
  18. In order to further investigate the role of axudl in human tumor carcinogenesis and the potential association between the axudl gene expression status and the stimulation of transforming growth factor beta in human cancers, the present study was performed in three aspects as follows : ( 1 ) cloning full length enconding region cdna of axudl and construction of eukaryotic vector that expression the fusion protein of axud1 and influenza virus hemagglutin ha epitope tag ; ( 2 ) exploring the time and dose effects of tgf - 1 on the expression - of axudl gene in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and studying the effects of overexpression of axud1 on the expression of cell cycle and apoptosis related protein in hepg2 hepatoma cells ; ( 3 ) construction and expression of human axudl in e. coli m15. the following main results and conclusions can be obtained from the present study : 1. the full length ecnoding region of human axudl cdna from human peripheral blood lymphocytes was successfully cloned using one step rt - pcr method, and constructed into a eukaryotic expression vector which can be expressed a ha - axud1 fusion protein with axud1 and influenza virus hemagglutin ha epitope tag. the recombinant plasmid was identified by polymerase chain reaction, restriction endonuclease maping and sequencing, this expression vector might be instrumental to further study the function of axud1 protein in tumor cells

    為了進一步研究axud1在人類腫瘤發生中的作用及axud1基因的表達狀況與tgf -介導的信號通路的關系，本實驗研究分為三個部分： （ 1 ） axud1基因cdna全長編碼區的克隆和ha表位標記的axud1基因表達載體的構建； （ 2 ）探討肝癌細胞hepg2和肺腺癌spc - a1細胞中tgf - 1誘導的axud1基因表達的時間、劑量效應以及誘導表達的可能機理，並研究axud1的過表達對細胞周期和細胞凋亡相關蛋白表達的影響； （ 3 ） axud1原核表達載體的構建及其在大腸桿菌中的表達。本實驗的主要結果和結論如下： 1利用一步法rt - pcr成功地從人類外周血淋巴細胞中克隆出axud1基因編碼區cdna ，並將其構建入真核表達載體中，編碼的ha - axud1融合蛋白帶有流感病毒凝血素ha的表位標記肽段。
  19. When irradiation response and dose are linear, total dose radiation and post - irradiation annealing at room temperature are determined for one random by choosing absorbed dose rate, and total dose effect at other absorbed dose rate can be predicted by using linear system theory

    研究結果表明，輻射響應與吸收劑量成線性關系時，在實驗室選用任一特定劑量率進行總劑量輻射和輻照后室溫退火，可以通過線性響應理論模擬其它劑量率輻射下的總劑量效應。
  20. The main topics in this thesis are as following : presenting details of the microbeam facility, mc 2000, microscope stage, venus - 1 language, modeling on the control program based on the requirements analysis, the control structure and flow chart, the main frame for the integrated program, utilizing acti vex control to implement serial communication between the computer and mc 2000, seamless integration between vb application and matlab, probing into some factors that may influence the controlling precision and providing some methods to solve them

    與此同時，對實驗過程中產生的一系列實驗數據進行必要的分析，為進一步進行離子束生物工程中的誘變方向性問題和估計低劑量電離輻射的生物體效應研究提供理論依據。作者承擔了微束裝置計算機控制系統的設計工作，完成了asipp微束裝置計算機控制系統的系統設計、主程序以及樣本架控制模塊的設計；提出並實現了提高裝置通量的相關優化策略等。
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