力肽 的英文怎麼說
中文拼音 [lìtài]
力肽
英文
ala-gln-
Effect of calcitonin gene - related peptide on myocardial mechanics of severely scalded rats
降鈣素基因相關肽對嚴重燙傷大鼠心肌力學變化的影響Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants
血吸蟲病疫苗研究已有60多年的歷史,大致經歷了死疫苗、活疫苗(照射致弱尾蚴疫苗)和基因工程疫苗等研究階段,產生了一些who / tdr推薦認為很有希望的疫苗候選分子,如谷胱甘肽- s -轉移酶( gst ) 、副肌球蛋白( sm97 ) 、照射致弱疫苗抗原5 ( irv - 5 ) 、磷酸丙糖異構酶( tpi ) 、曼氏血吸蟲膜內在蛋白( sm23 )和脂肪酸結合蛋白( fabp , sm14 )等,但其對宿主的保護作用均不甚理想,未能穩定地達到40或以上的保護力水平,因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑,進一步提高其保護力。Magical fire ( eye doctor ) looks at well - being cream of sticking drawing tradition traditional chinese medicine formula famous and precious in tsinghua, is tied in wedlock modern up - to - date medicine result of scientific research, the various chinese medicinal crop famous and precious being carefully chosen, adopt the modern nano - technology and target to poison a technology to being given to, let various active material, tiny molecule, nutrition factor glutathione etc. guide medicine it is all right for to go ahead, the brute force passes through blood eye parclose, make pesticide effect reach nidus directly location, prompt the nutrition replenishing an eye with the part ( include ciliary muscle, retina, crystalline lens, optic nerve ), active eye part cell, improve eye part immunocompetence and oxidation resistance, boost an eye part organizing an assimilation of the new and excretion of the old, microcirculation improving and restoring an eye part, thereby reach eliminate look at strain, purpose improving and improving sight
清華神火視康貼汲取傳統中藥名貴配方之精華,結合現代醫藥最新科研成果,精選多種名貴中藥材,採用現代納米技術和靶向給藥技術,讓多種活性物質、微分子、營養因子谷胱甘肽等引藥上行,強力穿透血眼屏障,使藥效直達病灶部位,迅速補充眼部(包括睫狀肌、視網膜、晶狀體、視神經)的營養,激活眼部細胞,提高眼部免疫能力和抗氧化能力,促進眼部組織新陳代謝,改善和恢復眼部微循環,從而達到消除視疲勞,改善和提高視力的目的。The main study in this paper included as follows : the content and distribution of heavy metals in sediments and benthic organisms from the sewage stream in guangzhou city ; the acute toxicity and joint toxicity of mercury and selenium to swordtail fish ( xiphophorus helleri ) ; the damage of mercury to the indexes of antioxidant system in the gills and livers in swordtail ( including the measurement of the activities of total antioxidative capacity [ t ~ aoc ], superoxide dismutase [ sod ], glutathione peroxidase [ gsh - px ] and the concentration of malondiald - ehyde [ mda ] ) and the relief effects of selenium on it, as well as the physiological damage of mercury on the tissues, namely : the antagonistic effect of na + - k + ~ atpase activity on the tissues between selenite and mercury, and the ultrastructural damage under the exposure of mercury
研究內容主要有:廣州市河涌沉積物及底棲生物體內重金屬含量及評價;汞和硒對劍尾魚的急性毒性和聯合毒性及安全濃度的評價;汞對劍尾魚鰓和肝臟中抗氧化系統的毒性,包括對總抗氧化能力、超氧化物歧化酶、谷胱甘肽過氧化物酶活力及丙二醛含量的測定及硒對其保護作用;汞對劍尾魚組織生理毒性即:汞對na ~ + - k ~ + atpase活力的影響及硒的保護作用和汞和對劍尾魚組織超微結構的損傷等。以高氯酸?硝酸消化法和火焰原子吸收分光光度法測定了廣州市河涌沉積物和底棲生物中重金屬含量。Effect of soy peptides on hemodynamics in isolated working rat hearts
大豆肽對大鼠離體工作心臟血流動力學的影響The extracted marrows ganoderma lucidum and semen zizyphi spinosae contained in threesss can regulate secretion of hydrocortisone in human body and reduce excitation of human body during nighttime ; in addition, ganoderma - lucidum spores and semen zizyphi jointly stimulate secretion of sleeping - inducting peptide in body. improve rate of " high efficient sleeping quality and immunity. recover and strengthen mental strength, mental strength and vigor. through sleeping. the psychlogy and physiology return to the youth level
「索萊爾」多元明膠囊中所含的靈芝和酸棗仁提取精華,能調節人體內皮質醇的分泌,降低人體在夜間的興奮度;此外靈芝孢子粉和酸棗仁共同作用,能夠在體內刺激「睡眠肽」和格里酶「的分泌,有效促進「高能睡眠」率,延長「高能睡眠」時間,從而達到全面改善睡眠質量,提高免疫力,使體力、腦力、精力得到迅速恢復和加強,通過睡眠將生理及心理狀態調整到青春期水平。[ conclusion ] taken together, these data suggested that two peptides gwyydal and vasavfysalve were effective mimickers of vegf and these peptides maybe potent inhibitors of kdr and offer a hope for the construction of tumor vaccine
而且該模擬抗原表位可能與huvec上表達的vegf受體結合,從而抑制了vegf的促huvec生長作用。這為進一步定位vegf抗原表位,研究vegf受體結合抑制肽,設計腫瘤疫苗提供了有力的基礎。This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白質分子設計的理論和方法研究避孕疫苗,將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合,獲得新抗原- 35肽序列;並在合成、純化後分別與弗氏佐劑、免疫刺激復合物( iscoms )混合后免疫不同遺傳背景的雌性小鼠,觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變:以及在ivf下,新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。The experimental method includes selecting pure complexes of histidine - containing or cysteine - containing materials, from c - and n - terminal group of these amino acids to link to a group which have color or fluorescence or ultraviolet absorption, elucidating their binding affinity, fluorescence or uv - visible spectrum properties with zinc at physiological concentration and to elucidate their structure in the solid state via infrared spectroscopy. with the help of the concerned the data, the analysis was done to prove whether it can be applied to the zinc detection, in other words, whether it can be used as a new fluorescence probe for zinc detection
本實驗首次選用在生物體內與zn ~ ( 2 + )鍵合能力很突出的物質? ?組氨酸和半胱氨酸,採用類似於多肽合成的方法,在其羧基或氨基分別嫁接上一個帶有標記的基團,生成穩定的共價鍵化合物;在此化合物中模擬生理濃度條件加入鋅離子,通過紅外圖譜、紫外圖譜或熒光圖譜的變化分析鋅離子對標記基團是否產生影響,再結合有關數據分析其是否適合檢測鋅離子,即是否可能作為新的鋅離子熒光探針。Candesartan is a highly selective angiotensin type receptor blocker, mainly used in the treatment of hypertension and heart failure
摘要坎地沙坦是一個高選擇性血管緊張肽受體拮抗藥,主要用於高血壓和心力衰竭的治療。Phage display describes a selection technique in which a peptide or protein is expressed as a fussion with a coat protein of bacteriophage, resulting in display of the fused protein on the surface of the virion, while the dna encoding the fussion resides within the virion
自1985年gpsmith首次提出噬菌體展示技術以來,隨著生物技術的發展,噬菌體隨機肽庫已成為研究分子間相互作用的有力工具,特別是在抗原表位研究方面。After treatment with bfa, immunoflurescence labeling and confocal laser scanning microscopy indicated that the cytoplasmic dynein intermediate chain - like protein in lily pollen tube was insensitive to bfa treating, but spectrin - like protein was sensitive to it under the same condition
用bfa處理百合花粉管后,通過免疫熒光標記及激光共聚焦掃描顯微鏡觀察發現類細胞質力蛋白中間鏈對bfa不敏感;同樣的處理發現類紅膜肽對bfa敏感。Molecular enzymology, including structure and function of enzymes, kinetics of enzyme action, inhibition, inactivation and activation, regulation mechanism of enzymatic activity, inhibitory mechanism ; exploitation and applications of enzyme products ; folding and unfolding of proteins ; biochrome ; anticancer polypeptide
分子酶學,包括酶的結構與功能、酶作用動力學、抑制動力學、失活動力學、激活動力學、酶活力調控機理、抑制作用機理;酶產品的開發與應用;蛋白質折疊與去折疊;生物色素;抗癌多肽Structure and function of enzymes ; kinetics of enzyme action, inhibition, inactivation and activation ; regulation mechanism of enzymatic activity ; exploitation and applications of enzymes and inhibitors ; folding and unfolding of proteins ; anticancer polypeptide ; canceration mechanism ; proteomics
酶的結構與功能、酶作用動力學、抑制動力學、失活動力學、激活動力學、酶活力調控機理、抑制作用機理;酶產品及酶抑制劑的開發應用;蛋白質折疊與去折疊;抗癌多肽;癌變機理;蛋白質組學These findings of the specific ctls epitopes in irbp and pedf may lead to improved understanding of the pathogenesis of uveitis. our study also provides a strategy to identify specific ctls epitopes within tumour antigen, which is helpful to make tumour vaccine for the patients
本研究也為尋找腫瘤抗原中具有誘導特異性ctls能力的肽片段提供了一種策略,為制備肽片段腫瘤疫苗提供了理論基礎。At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
但是,學者們發現這一療法存在著如下的缺陷:單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用,且有誘導免疫耐受的潛在危險,有時反而會促進腫瘤的生長;事先需對患者的hla單倍型進行鑒定,以確定ctl表位與hla單倍型是否匹配,目前尚缺乏能與所有hla單倍型相匹配的ctl表位,從而限制了這一療法的應用;這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞,但對腫瘤細胞的殺傷能力較弱:這種l表位抗原肽缺乏cd4汀h細胞相關的表位,因此,不能誘導有效的th細胞免疫應答。Effects of yiqi kaimi recipe on gastrointestinal motility and neuropeptides in rats with colonic slow transit constipation
益氣開秘方對結腸慢輸型便秘大鼠腸動力和腸神經肽的影響A number of peptides important in normal bone formation, such as members of the transforming growth factor - beta superfamily, are not satisfactory for this purpose either because their beneficial effects are predominantly local or there is systemic toxicity associated with their administration
在正常的骨頭構成重要的許多肽,例如轉變的生長因素貝它總科的成員,不圓滿為與他們的管理因為他們的受益的作用是突出本地的或有全身的,所以毒力聯系了的這個目的。Effects of calcitonin gene - related peptide and nerve growth factor on spatial learning and memory abilities of rats following focal cerebral ischemic - referfusion
降鈣素基因相關肽和神經生長因子對局灶性腦缺血再灌注大鼠空間學習記憶能力的影響Mc cormick pa, dick r, siringo s, et al. octretide reduces gastrical blood flow in cirrhosis patients with portal hypertension. eur j gastroenterol hepatol, 1996., 8 : 2189
張達榮,蕭樹東,李繼強,等.奧曲肽和垂體后葉素對門脈高壓血流動力學影響.中華消化雜志, 1995 , 2 : 85分享友人