抗腫瘤因子 的英文怎麼說

中文拼音 [kàngzhǒngliúyīnzi]
抗腫瘤因子 英文
antitumor agent
  • 抗 : Ⅰ動詞1 （抵抗; 抵擋） resist; combat; fight 2 （拒絕; 抗拒） refuse; defy 3 （對等） contend with...
  • 腫 : Ⅰ名詞（隆起處） swelling Ⅱ動詞（突起） swell; be swollen
  • 瘤 : 名詞（瘤子） tumour
  • 因 : Ⅰ動詞[書面語] （沿襲） follow; carry on Ⅱ介詞1 [書面語] （憑借; 根據） on the basis of; in accord...
  • 子 : 子Ⅰ名詞1 （兒子） son 2 （人的通稱） person 3 （古代特指有學問的男人） ancient title of respect f...
  • 腫瘤 : tumour; core （綿羊體內的）; neoplasm; phyma
  1. New york ( reuters health ) jan 03 - although a clinical response was observed, anti - tumor necrosis factor ( tnf ) therapy with etanercept did not appear to be superior to methotrexate for the treatment of rheumatoid cachexia, according to findings published in the december issue of the american journal of clinical nutrition

    紐約（路透社健康） 1 . 03 -根據美國臨床營養雜志11月刊的報道，在觀察了臨床表現后發現，用依那西普進行抗腫瘤壞死因子（ tnf ）治療並不比甲氨喋呤治療類風濕性惡病質更具優勢。
  2. Luteolin is an important member of the flavonoid family

    摘要木犀草素是一種植物黃酮，是抗腫瘤的啟動因子。
  3. Luteolin can also sensitize a number of apoptosis - inducing factors by unique mechanisms

    木犀草素還能增敏多種致凋亡因子，具有多靶點抗腫瘤的潛力。
  4. Vascular endothelial growth factor and the effects of endostatin on the inhibition of tumor angiogenesis in treating hepatocarcinomas

    血管內皮生長因子和內皮抑素在肝癌抗腫瘤相關血管治療中的作用
  5. The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased

    結合以上創建的方法和免疫熒光流式細胞術，用k562細胞株可溶性分泌物（上清）對外周血單個核細胞（ pbmc ）進行培養以模擬體內微環境，然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究，結果發現用腫瘤上清培養的pbmc細胞數量下降明顯，但同時對其有激活作用，且呈劑量依賴性；細胞數的下降主要是由細胞壞死和凋亡引起的，腫瘤上清對細胞周期沒有阻斷作用，反而略有促進作用； t細胞亞群比例增加，並促進表達th1 、 th2細胞因子。
  6. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  7. Indeed, researchers led by jain have shown that antiangiogenic factors can “ normalize ” tumor vasculature before killing it by pruning excess, inefficient vessels while leaving efficient vessels temporarily intact

    的確，由詹恩所領導的團隊發現：抗血管新生因子在殺死腫瘤之前，會修剪過度生長、沒有效率的血管，並讓有效率的血管暫保無恙，而使腫瘤的血管系統正常化。
  8. Dendritic cells ( dc ), the initiator and modulator of immune response, are the most powerful professional antigen - presenting cells ( apc ). recent studies indicated that dc have the most power to activate tumor specific ctl, therefore, dc are applied in the therapy of tumors, e

    機體的抗腫瘤免疫主要為t淋巴細胞所介導， t細胞的致敏、激活、擴增和對腫瘤細胞的殺傷作用均有賴于抗原遞呈細胞腫瘤遞呈相應的抗原肽及相關因子的參與。
  9. Human trail is a new member of tnf superfamily, which can specially induce cancer cell to apoptosis, but has none effect on normal cell. it is a new potential anti - cancer drug. the soluble functional part of trail gene was modified based on the partial principle code found in pichia pastoris

    人的trail基因是新發現的腫瘤壞死因子tnf超家族的成員，它具有專一的誘導癌細胞調亡的作用，而對正常細胞沒有任何殺傷作用，是一種很有潛力的抗癌藥物。
  10. Dcs play a pivotal role in the development of antitumor immunity. t lymphocytes immune response induced by direct antigen - pulsed dcs can not maintain longer for peptides - mhc department or mhc molecules degeneration. the method of dcs loading with tumor antigen gene is another potential approach to enhancing and maintaining immune response

    在用抗原直接刺激dc時，由於抗原- mhc復合物解離或細胞mhc分子降解而不能維持所誘導的t細胞免疫應答，藉助載體把腫瘤抗原基因導入dc后腫瘤抗原在dc內的持續表達能增強其抗原提呈能力並能維持所誘導的免疫效應。
  11. Methods employed to prepare vaccine include rumor cells genetically modified with cytokines, costimulatory molecules and tumor antigenic peptides, dendritic cells ( dc ) primed with tumor antigens in vitro or genetically modified with tumor antigens, or fusion of tumor cells with antigen presenting cells ( apc )

    現有的比較受到關注的制備腫瘤疫苗的方法有各種細胞因子、共刺激分子、腫瘤抗原肽等基因修飾的腫瘤細胞疫苗；體外抗原致敏的或腫瘤抗原肽基因修飾的樹突狀細胞疫苗；腫瘤細胞與抗原遞呈細胞融合疫苗等。
  12. Effects of boschniakia rossica extract on the serum antioxidative activities and tumor necrosis factor in initial stage of rat chemical hepato - carcinogenesis in rats

    草蓯蓉提取物對大鼠肝癌前病變模型血清抗氧化酶活性及腫瘤壞死因子的影響
  13. 2 ) basis of upon studies, we have also designed and sythesized the mutation ii of the cmiv that been greatly changed in the 3 " of the gene comparing with nature cmiv : the ht gf3 ( the third loop region of htgf2 specifically binding to egfr receptor ) was fused to 3 " of gene of cmiv through a flexible linker. the gene of the mutation ii of cmiv was sequenced and clonged to the vector of ptxfus to fuse to the 3 " of gene of thioredoxin

    二、在以上研究的基礎上，對cmiv抗菌肽的c端進行較大的改造，即將與腫瘤細胞過度表達的表皮生長因子受體（ egfr ）具有高親和性的因子多肽tgf _ 3通過疏水柔性接頭連接在抗菌肽cmiv的c端，設計完整的基因，並在大腸桿菌中利用ptxfus表達載體與硫氧還蛋白進行可溶性融合蛋白表達。
  14. Patients in the control group were treated with comprehensive therapy including symptomatic supportive treatment, antiinfective therapy and artificial liver plasmapheresis etc., while those in the treated group were orally taken szrd additionally. patients condition of sleeping and changes of total bilirubin prothrombin activity, tumor necrosis factor and interleukin1 il1 were observed before and after treatment, and the adverse reactions were observed as well

    對照組採用對癥支持抗感染人工肝血漿置換等綜合治療，治療組在此治療基礎上，加用酸棗仁湯口服治療2周，觀察兩組患者睡眠情況，檢測治療前後血清總膽紅素tbil凝血酶原活動度pta腫瘤壞死因子tnf和白細胞介素1 il1等指標，並觀察藥物的不良反應。
  15. It is well known that tumor necrosis factor a ( tnfa ) can play very different character in defence mechnism of body and pathologic injury, in which it can inhibit or kill tumor cell, and induce inflammation against infection ; on the other hand, tnfa can be as a very important mediator to cause some serious pathologic processes such as septic shock, gvhr and some autoimmune diseases

    腫瘤壞死因子（ tumornecrosisfactor ， tnf ）具有對某些惡性腫瘤的抑制或殺傷作用，也是致內毒素性休克、急性移植物抗宿主病及一些自身免疫病的重要效應因子，因此tnf的改造和tnf拮抗劑的研究受到各國學者的重視。
  16. Macrophage is a kind of immune cell as well as accessory cell. it can function as antiinfection, anticancer, immune response and immunoregulation by phagocytosis, antigen presentation, cytokines secretion, lymphocyte activation, reactive oxygen and no production. it ' s an important part of body immune system

    巨噬細胞（ macrophage ）既是免疫細胞，又是輔佐免疫應答細胞，可通過吞噬、抗原呈遞、分泌細胞因子、激活淋巴細胞和產生活性氧、 no等作用而行使抗感染、抗腫瘤、免疫應答和免疫調節作用，是機體免疫系統的重要組成部分。
  17. The life span of mouse that were inoculated tumour cells was prolonged, and the body weight increase was slowed down by injection of xhl. meanwhile, the secretion of il - 2, tnf - a and ifn - r, that were relevant to antitumour, were enhanced by injection of xhl to mouse

    荷瘤小鼠腹腔注射xhl后，在一定程度上延長了小鼠的存活時間，減緩了荷瘤小鼠體重的增加速度，同時提高了和抗腫瘤相關的白細胞介素2 、腫瘤壞死因子-和干擾素-的分泌量。
  18. In summary, we used the cdna microarrays to analyze the differentially expressed genes in the arsenic trioxide induced k562 cells. our results further confirmed in gene expression level that growth arrest and apoptosis could be induced by arsenic trioxide. such induced apoptosis may also involve the functional inhibition of igf

    應用基因晶元技術研究aszo3作用前後k562細胞的基因表達變化，與以往的研究結果相一致，也是通過抑制細胞生長、誘導細胞凋亡而發揮抗腫瘤的作用，在這個過程中， aszo3可能對胰島素樣生長因子有抑制作用。
  19. Interferon - gamma ( ifn - y ) is a product of thl, cytotoxic t lymphocytes ( ctl ) and nk cells, and is one of the major effector molecules in cell - mediated immunity

    Y干擾素（ intederon唱amma ， ifn個）是由th 、 ctl及nk細胞等產生的th型細胞因子，在機體抗感染、抗腫瘤中發揮重要的作用。
  20. Inhibition of tumor - induced angiogenesis may represent an effective cytostatic strategy. angiostatin inhibits endothelial proliferation, angiogenesis, and tumor growth., so it is very important to receive a great deal of soluble, correctly folded, biologically ac

    Angiostatin已被證實是一種很具潛力的抗腫瘤生長和轉移的因子，因而若獲得大量具有高活性、高純度的angiostatin對腫瘤的治療會有重要的意義。
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