抗腫瘤效應 的英文怎麼說

中文拼音 [kàngzhǒngliúxiàoyīng]
抗腫瘤效應 英文
gvt
  • 抗 : Ⅰ動詞1 （抵抗; 抵擋） resist; combat; fight 2 （拒絕; 抗拒） refuse; defy 3 （對等） contend with...
  • 腫 : Ⅰ名詞（隆起處） swelling Ⅱ動詞（突起） swell; be swollen
  • 瘤 : 名詞（瘤子） tumour
  • 效 : Ⅰ名詞（效果; 功用） effect; efficiency; result Ⅱ動詞1 （仿效） imitate; follow the example of 2 ...
  • 應 : 應動詞1 （回答） answer; respond to; echo 2 （滿足要求） comply with; grant 3 （順應; 適應） suit...
  • 腫瘤 : tumour; core （綿羊體內的）; neoplasm; phyma
  • 效應 : [物理學] effect; action; influence
  1. Thermo effects raise the cytotoxicity of chemotherapy drug towards tumor cells. thermo fluid also provide hyperthermia thermotherapy

    .溫熱效應增強化療藥物對腫瘤組織的細胞毒性作用溫熱效應本身具有抗腫瘤作用
  2. Case reports are presented which strongly suggest an anti - tumor effect of a whey protein dietary supplement in some urogenital cancers

    泌尿生殖系統腫瘤之病例報告強烈提示應用乳漿蛋白膳食補助具有抗腫瘤效果。
  3. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  4. Quantitative structure - activity relationship is a method building a statistical model. the model can quantificationally predict structure - activity relationship of molecule, and bioactivity of new molecules can be known. structure of molecule, which is described by parameters in physical chemistry, biochemistry and quantum chemistry, includes functional group, minor structure, molecular fragment, chemical composition

    本文提出了一種定量構效關系的處理方法，即應用支持向量回歸方法解決定量構效關系，並且應用這種方法預測了芳香烴化合物生物降解度與喜樹堿化合物抗腫瘤生物活性，取得了比較令人滿意的結果。
  5. At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells

    但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。
  6. Dcs play a pivotal role in the development of antitumor immunity. t lymphocytes immune response induced by direct antigen - pulsed dcs can not maintain longer for peptides - mhc department or mhc molecules degeneration. the method of dcs loading with tumor antigen gene is another potential approach to enhancing and maintaining immune response

    在用抗原直接刺激dc時，由於抗原- mhc復合物解離或細胞mhc分子降解而不能維持所誘導的t細胞免疫應答，藉助載體把腫瘤抗原基因導入dc后腫瘤抗原在dc內的持續表達能增強其抗原提呈能力並能維持所誘導的免疫效應。
  7. To circumvent these deficits, novel antigen - delivery systems utilizing cytokine gene - modified tumor cells and dc or fusion of dc with tumor cells have resulted in induction of antitumor immunity. however, this u approach is difficult in some cases ( for example in breast cancer ) because only rarely has it been possible to isolate enough viable tumor cells from an individual to prepare the vaccine

    為了克服上述缺陷，有學者採用滅活的腫瘤細胞、腫瘤抗原提取物（包括腫瘤細胞裂解物、 it na和洗脫肽等）沖擊致敏dc或將腫瘤細胞與dc融合后再回輸體內以激發機體的抗腫瘤免疫應答，也取得了較好的療效。
  8. Logic suggests that by compromising the blood supply of tumors, antiangiogenic therapy would interfere with the effectiveness of these standard treatments

    按邏輯推論，抗血管新生療法會使得腫瘤的血液供應不良，也就會干擾那些標準療法的效用。
  9. It is well known that tumor necrosis factor a ( tnfa ) can play very different character in defence mechnism of body and pathologic injury, in which it can inhibit or kill tumor cell, and induce inflammation against infection ; on the other hand, tnfa can be as a very important mediator to cause some serious pathologic processes such as septic shock, gvhr and some autoimmune diseases

    腫瘤壞死因子（ tumornecrosisfactor ， tnf ）具有對某些惡性腫瘤的抑制或殺傷作用，也是致內毒素性休克、急性移植物抗宿主病及一些自身免疫病的重要效應因子，因此tnf的改造和tnf拮抗劑的研究受到各國學者的重視。
  10. This paper reviewed the progress of targeted therapy of cancer from points of view of western and chinese traditional medicine and clarified the multiple target effect of chinese materis medica of ant - angiogenesis of cancer, inducing apoptosis and inhibition of telomerase activity

    摘要從中西醫角度分別綜述腫瘤靶向治療的研究進展，闡述中藥在腫瘤治療中的抗腫瘤血管生成、誘導細胞凋亡和抑制端粒酶活性的多靶點效應。
  11. Unfortunately, tumor cells can secrete immunosuppressor factors ( such as il - 10, tgf - p, vegf ) to interfere with dc maturation and function. to overcome tumor - mediated inhibition of dc maturation and function in vivo, immunopotentiating cytokines ( such as il - 7, il - 12 ) were used for gene - modification of dc, which has proven to be an efficient way to treat cancer in animal models

    雖然有直接瘤內注射dc誘導抗腫瘤免疫效應的報道，但腫瘤局部往往是一個處于高度免疫抑制狀態的微環境，腫瘤細胞分泌的可溶性介質（如ill 、 tgf卜vegf等）能抑制dc的分化成熟，下調dc表面共刺激分子的表達和iliz的分泌，從而抑制dc的抗原提呈功能，亦對t細胞功能有顯著的抑制作用。
  12. Cinobutacini injection is widely used on the clinic, which has antitumor effects and immunity improvement, but the active ingredient needs to be studied further

    摘要華蟾素注射液是臨床應用較廣的抗腫瘤中藥制劑，具有抗腫瘤、增強機體免疫力等作用，但對其確切的有效成份仍需進一步研究。
  13. Additionally, many glycoproteins from natural plants are in themselves effective medications in depressing blood - glucose, enhancing immunological function, combating inflammation and repelling tumor etc. glycotechnology drugs have already been applied in clinic medicine

    另外，許多天然植物糖蛋白本身就是很好的藥物，具有降血糖、增強免疫、消炎、抗腫瘤等功效，以糖蛋白為基礎的重組蛋白藥物在臨床上也早已應用。
  14. On the other hand, the expression is repressed by the proto - oncogenes n - myc and c - myc, and in some cases the expression is also repressed by testosterone or dihydrotestosterone ( androgen ) at mrna level infering from all the references that can be obtained, the functions of ndrg family may be involved in cellular differentiation events > maintaining the balance of cell redox potential ( in oxidative stress condition or biological conversion process ), or counteracting cell malignant transformation, and so on

    綜合己有的文獻，推測ndrg家族可能參與細胞生長分化、維持細胞氧化還原電勢平衡（氧化應激或生物轉化） 、阻止腫瘤細胞惡化等。因此，研究其在細胞中的具體功能以及可能的信號通路將具有非常重要的意義。深人研究ndrgz在體內的組織細胞和亞細胞水平分佈特點及其功能，需要高效價和高特異性的ndrgz抗體。
  15. Mechanism of tumor cell - damaging effect of hematorophyrin actived by ultrasound

    超聲波激活血卟啉抗腫瘤效應機理研究
  16. When the body suffered from malignancy, on the one hand, tumor restrained cell immunity function, antibody ' s production and the body ' s immunity effect through inducing restraining t cell, so it accelerated tumor ' s growth, on the other hand, tumor induced body fluid restrained gene, which prevented t cell and nk cell from killing tumor and restrained lymphocyte to mitotic multiplication reaction, indeed it accelerated tumor ' s growth

    當機體一旦患上惡性腫瘤后，一方面腫瘤通過誘導抑制性t細胞，抑制細胞免疫功能及抗體的產生，抑制機體對腫瘤的免疫效應，從而使腫瘤逃逸機體的免疫監視，促進腫瘤的生長。另一方面，腫瘤通過誘導體液抑制因子阻止t細胞和nk細胞的等對腫瘤的殺傷作用，抑制淋巴細胞對有絲分裂原的增殖反應，甚至促進腫瘤的生長。
  17. Regulatory effect of secretory recombinant peptide pd - 1 - cell on the function of immune cells and its anti - tumor effect

    調節免疫細胞功能活性及抗腫瘤效應的研究
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