毒理基因組 的英文怎麼說

中文拼音 [dúlǐjīyīnzǔ]
毒理基因組 英文
toxicogenomics
  • 毒 : Ⅰ名詞1 （對生物體有害的性質或物質; 毒物） poison; toxin 2 （毒品） drug; narcotics 3 （姓氏） a s...
  • 理 : Ⅰ名詞1 （物質組織的條紋） texture; grain （in wood skin etc ） 2 （道理;事理） reason; logic; tru...
  • 因 : Ⅰ動詞[書面語] （沿襲） follow; carry on Ⅱ介詞1 [書面語] （憑借; 根據） on the basis of; in accord...
  • 組 : Ⅰ名詞1 （由不多的人員組成的單位） group 2 （姓氏） a surname Ⅱ動詞（組織） organize; form Ⅲ量詞（...
  1. Newcastle disease virus ( ndv ) strain 695, a thermostable nature avirulent strain, were replicated in embryonated chicken eggsand its rna was extracted from allantoic fluid. referred to the reported sequence of f gene, a pair of primers were designed and synthesized. f gene of ndv b95 strain was amplified by rt - pcr, the pcr products were checked by agrose gel electrophoresis and purified by agrose gel fracion method

    利用從國外引進的新城疫熱穩定性天然弱毒b _ （ 95 ）株接種spf雞胚繁殖病毒，經處理后提取病毒的基因組rna ，參考國內外發表的ndv融合蛋白基因序列，設計一對特異性引物，經反轉錄聚合酶鏈式反應（ rt - pcr ）擴增出約1700bp大小的特異性片段，將此片段回收純化后，利用t - a克隆技術將其克隆到pgem - t - easy克隆載體中，再轉化大腸桿菌jm109感受態細胞，轉化后經分子量比較、 pcr鑒定和酶切分析篩選陽性克隆。
  2. The purpose of this study was to clone the major structural protein vp3 gene of gpv hl isolate after pcr, and express by protokaryotic and eukaryotic expressing system, then develop molecuiar diagnostic reagent of goose piaque and construct recombillat fowlpox vina life vector vaccine

    利用pcr方法擴增和克隆gpvh1分離株主要免疫原性蛋白基因vp3 ，並對其進行原核和真核表達，是建立小鵝瘟分子診斷方法、構建vp3基因重組禽痘病毒活載體疫苗的基礎，具有極為重要理論和實踐意義。
  3. When cultured in vitro for 8 days, nscs were divided into three groups : the first one is the group to identify and evaluate nscs " property and proliferating capability ; the second one is the group to induce differentiation of nscs by egf, bfgf, 1 7 - estrodiol and atra respectively ; the third one is the group to investigate the toxicity of a p 25 - 35 and protective action of 1 7 - estrodiol against a. the above - mentioned groups were cultured continuely according to formerly conditions, then conducting the following experiments : 1. identification of nscs and evaluation of their proliferating capability brdu ( 5mol / l ) was added into the first group to label cells when group division was conducting

    3 . 3ap25一35和ap25一35 +雌激素作用后凋亡相關基因bcl一2 ， bax表達鄭州大學2003年碩七研究生畢業論文ap25 - 35對胚胎神經卜細胞的毒性和雌激素的保護作用對照處理組bel一2 、 bax均無表達;雌激素保護組bel一2及bax均有表達; ap毒性組僅有促凋亡基因bax表達，而無凋亡抑制基因be卜2表達。
  4. This paper expounds the progresses of the researches on the life science and relevant subjects, which include the research of cultivating the arterial vessel with fine cell tissue, the research on the genetically modified animal, the research on the pest control with bio - virus pesticide, the research on the death mechanism of protein and the diseases of immune system ( including cancer ), the research on anti - senile protein and the research on compound - type aids vaccine

    闡述了生命科學及其相關學科的研究進展，包括用細小細胞組織培製成動脈血管的研究、轉基因動物的研究、生物病毒農藥防治蟲害的研究、蛋白質死亡機理及免疫系統疾病（包括癌癥）的研究、抗衰老蛋白的研究以及復合型艾滋病疫苗的研究。
  5. The result shows that a vvibdv strain was obtained, the above work lay a important role for further studying on the molecular biological mechanism of antigenic drift and virulence variation of ibdv, molecular epedimiology, it also provided the basis for recombinant and gene deleted vaccine of ibdv

    本實驗可以幫助我們進一步探討ibdv抗原性漂移和毒力變化的分子生物學機制，追溯ibdv的起源，理解病毒的傳播方式。同時也為研製開發基因重組疫苗和缺失疫苗打下一定的基礎。
  6. On the basis of the safety system engineering theory. applying the dow fire & explosion index and the normal stability gauss mathematical diffusion model etc., combining with the practice of mouping port, the hazards during the handling and storage of liquid chemicals in bulk have been analyzed and the risks of fire explosion and leakage ( including water pollution and water pollution ) have been assessed. taking into account of insufficient consideration of the human factor in the dow fire & explosion index, the soft compensation coefficient has been raised

    本文以安全系統工程為理論基礎，運用道氏火災爆炸指數法、平均運動方程組以及常穩態高斯數學擴散模型，結合牟平港散化運輸、裝卸的實際，對牟平港散化儲運的火災爆炸危險性和毒物泄漏危險性（包括水污染性和大氣污染性）進行了定性和定量的分析評價。在評價程序上，針對道氏火災爆炸指數法中對人為因素和管理水平等考慮不足的問題，提出了軟補償系數的概念，找出了散化碼頭日常監督管理工作的重點。
  7. Results : compared to the model group, 689 genes were down - regulated obviously by the treatment of invigorating spleen and regulating qi, while 14. 0 genes by expelling toxin by cooling, and 186 genes by promoting blood circulation. screen 19 genes correlated with signal transduction among 163 known ones down - regulated by invigorating spleen and regulating qi

    結果：與模型組比較，各中醫治法下調最明顯的基因分別為：清熱解毒法明顯下調140個基因，活血化瘀法明顯下調186個基因，健脾理氣法明顯下調689個基因；在健脾理氣法明顯下調的163個已知基因中，篩選出19個與信號轉導相關的基因。
  8. Design : induced by administration of den solution, we got the rat liver cancers model to observe the regulation effects of invigorating spleen and regulating qi to genetic transcription, which is relevant to the transcription and signal transduction in genome of rats - liver - cancer tissues, controlled treatments about chemotherapy of medicine - ftorafurum, and the two tcm treatments including expelling toxin by cooling and promoting blood circulation to remove blood stasis

    方法：以den誘導大鼠肝癌形成為模型，以西藥喃氟啶化療、中醫清熱解毒、活血化瘀治法為對照治療，採用基因晶元技術，觀察健脾理氣法對大鼠肝癌組織基因組轉錄水平及信號轉導相關基因轉錄的調控作用。
  9. Two strains of prrsv were isolated from the swine infected with prrsv in shangdong province and daqing area, in order to clarify the source and genetic background of porcine reproductive and respiratory syndrome virus ( prrsv ) from different parts of china, thus providing theoretic basis for the study of vaccine against it. the prrsv was cultured on mark - 145 cells for 5 ~ ~ 6 passages. when the cpe was obvious, the virus was harvested and purified

    為了弄清我國不同地區prrsv的來源以及其遺傳學背景，為疫苗學研究提供理論根據，本研究在ch - 1a株完整的基因組獲得以後，從流行於我國山東（ sd ）和黑龍江大慶（ dq ）地區疑似prrs的豬體內分離到prrsv ，在mark - 145細胞上盲傳5 6代，細胞出現明顯病變以後，收獲病毒液，然後提純，提取全病毒rna ，經過反轉錄、 pcr擴增獲得結構基因orf2 7的目的基因片斷，然後與pmd - t載體連接，轉化，得到陽性質粒后進行測序，並將其與ch - 1a株進行了比較分析，同時對這兩個毒株的結構基因組的理化性質進行分析。
  10. The biologic toxins produced by bacteria and virus have important effects to organic metabolism and reproduction. the study on bacterial toxin at molecular level, especially, on complete nucleotide sequence determination of pathogenic micro - organism has make it possible to comprehend pathogenic micro - organism pathogenesis and its rule. recently complete nucleotide sequences of near ten bacteria have been examined

    細菌、病毒等所產生的生物性毒物對機體的代謝、繁殖機能有著重要的影響，目前對細菌毒素的研究比較透徹，已經上升到分子水平，特別是通過病原微生物全基因組序列的測定，使人們從更高層次上把握病原微生物的致病機理及其規律成為可能。
  11. Marc 145 cells were suitable for primary isolation and propagation of avian rotavirus. trypsin appeared essential for the enhancement of infectivity and the occurance of cytopathic effect ( cpe ). serum neutralization ( sn ) n electron microscopy ( em ) and analysis of genomic rna were done to identify and confirm the identity of rotavirus

    根據病毒形態、基因組的聚丙烯酰胺凝膠電泳、病毒中和試驗、動物回歸試驗，對分離的病毒進行了鑒定，並對分離病毒的生物學特性和理化特性作了部分研究。
  12. The article overviews the principles, methods, the effect factors of the tip meristem culture of sweet potatoes and its research progress, and points out the problem that it is unknown widely, its composition of culture medium is different because of varietal difference, virus infects sweet potatoes again and production cost is high

    摘要綜述了甘薯莖尖分生組織培養的原理、方法、影響因素及其研究進展，指出了莖尖組織培養存在的未被廣泛認識、由於品種差異造成的培養基成分不同、病毒再侵染、生產成本高等問題。
  13. Using the monoclonal antibody to rev and the anti - sera against the rev env gp90 - gst fusion protein. the molecular cloned virus was detected by ifa. we also amplified the gp90 from the cells infected with the molecular cloned virus by polymerase chain reaction. all these results indicated the recombinant plasmid containing the total rev genome cdna is infectious

    對snv株前病毒全基因組cdna克隆進行酶切，將酶切產物分別克隆進puc18中，分別將各個亞克隆進行測序，按照酶切位點和已知的部分序列以及rev物理圖譜將測得的序列進行拼接，完成了rev全基因組序列。
  14. No recipient of group a ( without any treatment, n = 5 ) or group b ( treated with adgfp, n = 4 ) died within three weeks after transplantation and severe acute rejection ( massive periportal infiltrate, endothelilitis, damage to biliary epithelium and severe tissue destruction ) was confirmed by pathological examination of the graft. in contrast, all recipients of group c ( treated with adhuctla4 - ig, n = 5 ) achieved lohg - term liver allograft survival ( > l50d )

    35 ，屍0刀5八而灌注攜帶融合基因a個ig的重組腺病毒組組， fi ? 5 ）受體鼠均能獲得長期生存（ 150天） ； a組與c組間、 b組與c組間，生存期均有顯著性差異』 （ p 0刀1人a組與b組，在術后8天行移植肝活檢，病理學檢查證實：移植肝均發生嚴重的細胞性排斥。
分享友人
分享到 Line

分享到臉書