細胞抑制因子 的英文怎麼說
中文拼音 [xìbāoyìzhìyīnzi]
細胞抑制因子
英文
non-specific t-cell suppressor factor- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 抑 : Ⅰ動詞(向下按; 壓制) restrain; repress; curb Ⅱ連詞[書面語]1 (表示抉擇) or 2 (表示轉折) but3 ...
- 制 : Ⅰ動詞1 (製造) make; manufacture 2 (擬訂; 規定) draw up; establish 3 (用強力約束; 限定; 管束...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 子 : 子Ⅰ名詞1 (兒子) son 2 (人的通稱) person 3 (古代特指有學問的男人) ancient title of respect f...
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
- 抑制 : 1 (控制) restrain; control; check; hold up; curb; stop; repress; bridle; choke; prehension; sup...
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Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4
- arrestin2是趨化因子受體的一種重要的調節蛋白,本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用,反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制, cxcr4介導的趨化作用則被明顯抑制。We showed here that axudl mrna expression was elevated by tgf - 1 treatment in a time and dose - dependent manner in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and also indicated that de novo protein synthesis was required for this response using the protein synthesis inhibitor cycloheximide, suggesting that axudl is a primary target of tgf - signalling
在hepg2和spc - a1細胞中, tgf - 1能明顯誘導這兩種細胞中的axud1基因的表達,而且表現出時間和濃度的依賴效應。同時,利用第一軍醫大學博士學位論文蛋白質合成的特異抑制劑還發現, tgf一pl誘導的axudl基因的表達過程需要新的蛋白質的合成,提示axudl基因是tgf一p信號通路的一個主要靶分子。Under suspension culture without cytokines, the putative eg clonies could be induced to form simple embryoid bodies. after long - time culture, these bodies began to differentiated into various cell types
將消化分散的類eg細胞在無分化抑制因子的類eg培養基中重懸培養, 3 4天後,可見部分細胞團形成簡單的胚體。Notch interaction with its ligands induces the cleavage of its intracellular domain ( ic ), and the notch ic translocates to the nucleus and binds to rbp - j, the mammalian homolog of su ( h ), to transactivate transcription of target genes such as e ( spl ) ( enhancer of split ), hesl ( hairy and enhancer of split ) and hes5 four notch receptors and their ligands are differentially and redundantly expressed in a variety of vertebrate tissues
它通過其識別序列( cogtgggaa )結合於受調控基因的啟動子區,在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。在沒有n 。 tch胞內段的情況下, rbpj可與包含sm盯( silencingmediatorforretlnoldandthyroidhormonereceptor )和組蛋白去乙酞化酶的轉錄輔助抑制復合物結合,當notch信號被激活時; rbpj可與n 。( 3 ) isolation and culture of human primordial germ cells ( pgcs ). human pgcs collected from gonadal ridges and mesenteries were grown on mouse feeder layers in the presence of human recombinant leukemia inhibitory factor ( lif ), human recombinant basic fibroblast growth factor, and forskolin as described previously. initially, pgcs were visualized by alkaline phosphatase activity staining
( 3 )人類pgcs的分離和培養從4 10周齡藥物流產胚胎的生殖嵴和腸系膜組織中分離原始生殖細胞( primordialgermcells , pgcs ) ,培養在添加人重組白血病抑制因子( lif ) 、人重組堿性成纖維細胞生長因子( bfgf )和forskolin的小鼠飼養層細胞上。In this study, the expression of nfkb p65 and ikba ( inhibitory kappa b alpha, ikba ) in poly - morphonnucleared cells, mononuclear cells and fibroblastic cells during rat skin contusion repair will be investigated using immunohistochemical technique and the relationship with contusion will be revealed, which can provide the theorical evidence to identify the contusion age
I b因其抑制nf b活性,也越來越受到人們的重視,故本實驗應用免疫組織化學方法觀察nf b家族的重要成員nf bp65與其抑制因子i b在大鼠皮膚挫傷后不同時間在多核粒細胞、單核巨噬細胞及成纖維細胞中的表達變化,揭示其與皮膚挫傷時間的關系,為皮膚挫傷時間的判定提供新的理論依據。They are positive regulating proteins and play a very important role in the development of neoplasma. cki are negative regulators taking part in cell cycle, which can directly or indirectly combine with the corresponding cdks to inhibit their activity. cyclin - cdk - cki constitutes a complex network regulating cell cycle
細胞周期蛋白依賴性激酶抑制因子( cyclindependentkinaseinhibitors , cki )可直接抑制相應的cdk活性或通過與cyclin競爭性結合cdk而起到抑制cyclin - cdk復合物的活性,從而作為負性調節因子參與細胞周期調控。Hello, restrain in marrow period it is to should avoid to affect, had done nurse measure, if luck is white, can use the remedy with white hurried namely again, indigestion fall bead cell stimulates factor to wait, also can undertake recuperating with chinese traditional medicine, be in commonly stop 10 days of or so marrow after changing cure to begin to restore, need not too anxious
你好,在骨髓抑制期一是要避免感染,做好護理措施,再就是可以應用促白的藥物如瑞白、積落粒細胞刺激因子等,也可以用中藥進行調理,一般在停化療后10天左右骨髓就開始恢復,不必過于著急。The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser ctcf, and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction, cell - cycle control, chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions
鑒定出的蛋白包括多個與轉錄調控相關的鋅指蛋白,如鋅指蛋白198 、 263 、 14 、 224 、 zf6 、轉錄抑制因子ctcf樣蛋白、幻肚pple樣鋅指蛋白等:兩個含金屬蛋白酶結構域和整合素結合結構域的家族成員adam28和adam17 ;兩個整合素家族成員pz整合素和含十個egf樣結構域的整合素( tied ) ;與細胞信號轉導通路有關的蛋白;與細胞周期調控有關的蛋白;與染色體重塑和基因轉錄抑制有關的蛋白;細胞骨架蛋白以及其他功能未明的蛋白等。Introduction protein kinase c ( pkc ) is a number of serine / threonine kinase family which play central regulatory roles in a multitude of cellular processes, including cell proliferation, cell cycle progression, differentiation, apoptosis. increasing evidence from studies using in vitro and in vivo systems suggests that pkc is a key regulator of critical cell cycle transitions, including cell cycle entry and exit and the gl and g2 checkpoint
前言細胞周期是細胞增殖、分化的一個重要過程,它的啟動與進程受到嚴格調控,參與調控的因子不僅包含起正調控作用的細胞周期素( cyclins ) 、細胞周期蛋白依賴性激酶( cyclin - dependentkinase , cdk ) 、還有起負調控作用的cdk抑制因子( cyclin - dependentkinaseinhibitor , cki ) 。Abstract : objective : to determine if 24 - hour blood concentrations of macrophage migration inhibitory factor ( mif ), soluble cd14, and cd163 receptors could predict complications associated with acute pancreatitis ( ap )
摘要:目的:確定巨噬細胞移動抑制因子( mif ) 、可溶性cd14 、 cd163受體的24小時血藥濃度能否預測急性胰腺炎( ap )的相關並發癥。Leukocyte migration inhibitory factor
白細胞遊走抑制因子Progression of the cell cycle depended on the activity of a series of protein complexes composed of cyclins and cyclin - dependent kinases ( cdks ). the activity of cyclin - cdk complexes was regulated by a group of cdk inhibitors ( ckis )
細胞周期進程決定於稱之為調節亞基的周期素( cyclins )和稱之為催化亞基的周期素依賴的蛋白激酶( cdks )的結合與相互作用,同時也受到細胞周期的負調控因子? cdks的抑制因子cdis家族成員的調控。Within the family of angiogenesis inhibitors, angiostatin, an endothelial cell - specific inhibitor, has been demonstrated to be the most potent
在血管生成抑制因子的家族中血管抑素( angiostatin )作為內皮細胞特異性的抑制劑已顯示出強大的作用。Discussions angiogenesis, an essential process for tumor growth, is regulated by endothelial proliferation factors and their inhibitors such as angiostatin
討論血管生成對于腫瘤生長來說是一個必需的過程,受內皮細胞增殖刺激因子和抑制因子的共同調控。Angiostatin is a angiogenesis inhibiting factor derived from tumor, which can potently inhibit endothelial cell proliferation and migration and has an important application value in the treatment of solid tumor
摘要血管生成抑制素是腫瘤衍生的血管生成抑制因子,能有效地抑制血管內皮細胞的增生和遷移,在實體瘤的治療中有重要的應用價值。In summary, we used the cdna microarrays to analyze the differentially expressed genes in the arsenic trioxide induced k562 cells. our results further confirmed in gene expression level that growth arrest and apoptosis could be induced by arsenic trioxide. such induced apoptosis may also involve the functional inhibition of igf
應用基因晶元技術研究aszo3作用前後k562細胞的基因表達變化,與以往的研究結果相一致,也是通過抑制細胞生長、誘導細胞凋亡而發揮抗腫瘤的作用,在這個過程中, aszo3可能對胰島素樣生長因子有抑制作用。Liao ey, luo xh, su x. comparison of the effects of 17beta - e2 and progesterone on the expression of osteoprotegerin in normal human osteoblestlike cells [ j ]. j endocrinol invest, 2002 ; 25 : 785 - 90
羅湘杭,廖二元,周后德,等.雌二醇對人成骨樣細胞基質金屬蛋白酶及其抑制因子的作用[ j ] .中華內科雜志, 2000 ; 39 : 243 - 6By cell transfection and kinase assay, we found that sh2a may be an inhibitor and play an important role in some key step of pkc signal transduction
二一sh ,經過細胞轉染和激酶活性檢測,結果提示, sh基因很可能作為一種抑制因子,在pkc信號轉導通路中某些關鍵環節起著調節作用。When the body suffered from malignancy, on the one hand, tumor restrained cell immunity function, antibody ' s production and the body ' s immunity effect through inducing restraining t cell, so it accelerated tumor ' s growth, on the other hand, tumor induced body fluid restrained gene, which prevented t cell and nk cell from killing tumor and restrained lymphocyte to mitotic multiplication reaction, indeed it accelerated tumor ' s growth
當機體一旦患上惡性腫瘤后,一方面腫瘤通過誘導抑制性t細胞,抑制細胞免疫功能及抗體的產生,抑制機體對腫瘤的免疫效應,從而使腫瘤逃逸機體的免疫監視,促進腫瘤的生長。另一方面,腫瘤通過誘導體液抑制因子阻止t細胞和nk細胞的等對腫瘤的殺傷作用,抑制淋巴細胞對有絲分裂原的增殖反應,甚至促進腫瘤的生長。分享友人