細胞粘連蛋白 的英文怎麼說

中文拼音 [xìbāoniánliándànbái]
細胞粘連蛋白 英文
cell adhesion protein
  • 細 : 形容詞1 （條狀物橫剖面小） thin; slender 2 （顆粒小） in small particles; fine 3 （音量小） thin ...
  • 胞 : Ⅰ名詞1 （胞衣） afterbirth2 （同一個國家或民族的人） fellow countryman; compatriot Ⅱ形容詞（同胞...
  • 粘 : 粘動詞（粘附） glue; stick; paste; adhere to; bond
  • 連 : Ⅰ動詞1 （連接） link; join; connect 2 （連累） involve （in trouble）; implicate 3 [方言] （縫） ...
  • 蛋 : 名詞1. （鳥類或龜、蛇類所產的卵） egg 2. （像蛋形的東西） an egg-shaped thing 3. （辱罵之詞）
  • 白 : Ⅰ形容詞1 （似雪的顏色） white 2 （清楚; 明白; 弄明白） clear 3 （空的; 沒加他物的） pure; clear; ...
  • 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
  • 粘連 : adjoin; adhesion; synechia; adhaesio; accretion; anchylo-; ankylo-; ancylo-
  • 蛋白 : 1. （卵中透明的膠狀物質） egg white; albumen; gary2. [生物化學] （蛋白質） protein
  1. There was no difference in other biologic characteristic of mscs between the two separation method, such as cell anchorage ratio and clone formation ratio. ( 2 ) plga film presented uniformity frame with no protuberance and fissure under scanning electron microscopy ( sem ). big aperture with smooth wall and average 400 m i n size running - through each other was observed in porous plga substrate, around the big aperture there were many round micropores about 5 m size. all of the structure were equal and uniform, which satisfied the further research work. ( 3 ) mscs adhesion at earlier time was promoted by biotiegenrafter 3h, cell number was ( 1. 5 0. 18 ) 105 in the plga film coated with biotiegen group, which was significantly higher than that in plga film group ( p < 0. 01 ) and higher than that in coverslip group ( p < 0. 05 ), which cell number was ( 1. 04 0. 21 ) 105. after 6h and 12h biotiegen could not promote cell adhesion, and cell proliferation and alkaline phosphatase ( alp ) activity were not promoted dramatically during 9 days. ( 4 ) cell adhesion was promoted by fibronectin or collagen type i

    G ） i型膠原、纖維粘連蛋白促進細胞增殖，細胞接種后3 、 6 、 gd三個檢測時間點，實驗組細胞均明顯高於對照組。與1型膠原相比，纖維粘連蛋白刺激作用更強。 ） i型膠原、纖維粘連蛋白尚能誘導mscs細胞向成骨細胞分化，不僅表達成骨細胞標志物ocn 、 alp 、 opnmrna ，而且堿性磷酸酶活性明顯增高，堿性磷酸酶及鈣結節7第四軍醫大學博士學位論文一染色均強陽性， i型膠原組mscs細胞堿性磷酸酶活性較fn組更高，有顯著性差異；同時，兔疫組化染色表明，經纖維粘連蛋白作用的mscs1型膠原表達陽性。
  2. Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription

    當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后，就與ajs發生解離而游離到細胞漿中，此時細胞的粘附功能也發生障礙，游離到胞漿中的-連環蛋白，一部分被抑癌因子apc降解，一部分則轉移到細胞核內，與核內的轉錄因子tcf lef結合，啟動與細胞增殖有關的基因轉錄。
  3. Objective : to study the expression of proliferating cell nuclear antigen ( pcna ) and fibronectin ( fn ) in placenta of early abortion

    摘要目的：觀察增殖細胞核抗原、纖粘連蛋白在早期自然流產患者胎盤中的表達情況。
  4. Results : the expression of pcna and fibronectin in placenta of 30 patients with early abortion was significantly reduced ( p < 0. 05 )

    結果：早期自然流產患者較正常早期妊娠胎盤中增殖細胞核抗原、纖粘連蛋白的表達減弱（ p < 0 . 05 ） 。
  5. Methods : the expression of pcna and fibronectin in placenta of 30 patients with early abortion were detected by immunohistochemistry

    方法：通過免疫組織化學方法觀察30例早期自然流產患者胎盤中增殖細胞核抗原、纖粘連蛋白的表達。
  6. There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose

    表皮生長因子（ egf ）能使p120 ~ （ ctn ）酪氨酸磷酸化，磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強； p120 ~ （ ctn ）在細胞內的分佈出現明顯的核內轉位， -連環蛋白也出現相似的變化。
  7. Catenin binds to the cytoplasmic tail of a transmembrane cell adhesion molecule - epithelial cadherin ( e - cadherin ) in epithelial cells and forms an adhesion complex [ e - cadherin - p - catenin ( or y - catenin ) - cc - catenin ] ( cadherin - catenin - complex, ccc ), this complex play an important role in maintaining epithelial cell adhesion. some catenins such as -, - and p120ctn catenins are also crucial in cell signaling, they play an important role in cell proliferation and cell apoptosis

    在上皮細胞內，連環蛋白均能與跨膜細胞粘附分子?上皮鈣粘蛋白（ e - cadherin ）的胞內肽段結合而形成了由上皮鈣粘蛋白- -連環蛋白（ -連環蛋白） - -連環蛋白組成的粘附連接體（ adherensjunctions ， ajs ） ，這種復合體對維持細胞正常的粘附功能是必需的。
  8. This study was performed to investigate whether overexpression of ecm components, laminin ( lm ) and collagen type iv ( col ) by tm cells may play a role in the development of outflow resistance

    實驗目的：研究小梁細胞合成的細胞外基質成分層粘連蛋白和iv型膠原是否影響房水流出阻力的形成。
  9. Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities

    因此將這些蛋白包被、固定到材料表面，觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節，並從以下方面進行探討： （ 1 ）採用不同原代細胞分離方法，研究其對mscs細胞的生物學特性影響。 （ 2 ）檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 （ 3 ）分別採用型膠原及纖維粘連蛋白（ fibronectin ， fn ）包被聚乙醇酸-乳酸共聚物（ poly （ 1actide - co - glycolide ） ， plga ）膜及多孔塊型plga材料，觀察細胞在單層或三維培養狀態下，型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。
  10. But in serum cell culture system, azphpia - pst surface could not detach cells completely. two typical serum proteins were used to find the reason

    用兩種典型的血清蛋白（牛血清白蛋白bsa和纖維粘連蛋白fibronectin ）模擬復雜的血清系統，研究血清蛋白對細胞脫附的影響。
  11. . . nearly all aspects of cell life are regulated by reversible protein phosphorylation. some examples include metabolic processes, gene regulation, cell cycle control, transport and secretory processes, the organization of the cytoskeleton, and cell adhesion

    蛋白可逆磷酸化幾乎可以調節所有的細胞活動，包括代謝過程、基因表達調控、細胞周期調控、運輸和分泌過程、細胞骨架的形成和細胞粘連。
  12. P120ctn is a more newly found catenin, studies revealed that it is also an important molecule in e - cadherin mediated cell - cell adhesion, and phosphorylated tyrosine in p120ctn were evidenced. translocation of p120ctn occurred in cancer cells and tissues. evidences showed that there were a key relationship between p120ctn translocation and tumoregenesis

    P120 ~ （ ctn ）是發現得較晚的一種連環蛋白，研究發現它也參與上皮鈣粘蛋白介導的細胞粘附過程並且不可缺少，同時p120 ~ （ ctn ）也和-連環蛋白一樣易於酪氨酸殘基磷酸化，磷酸化后的p120 ~ （ ctn ）也發生轉位，並與腫瘤的發生發展有密切關系。
  13. Also we found that p120ctn expressed mainly at cell membrane at cell - cell contact region in lo2 imortal human liver cells, while the molecule expressed mainly in cytoplasm and in nucleus in bel - 7404 human liver cancer cells, membrane expression reduced or disappeared in these cells. the molecule expressed at membrane, no immunoreaction was detected in cytoplasm or in nucleus in normal liver tissues

    而p一連環蛋白則變為胞核表達減少，胞漿和胞膜表達增加的有趣現象，提示p120cin在細胞粘附過程中是必需的，而且在信號轉導過程中它與p一連環蛋白可能存在某種競爭現象或其他聯系，有待進一步研究。
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