終末器官 的英文怎麼說
中文拼音 [zhōngmòqìguān]
終末器官
英文
terminal organ-
Transplantation has been developed to an effctive strategy for treatment of end stage diseases of multiple organs since 1950 ' s. despite success of current immunosuppressive drugs, transplantation immunologists and surgeons are still seeking to achieve tolerance to allograft. there are several different mechanisms such as clonal deletion, anergy, neglect, immuno regulation. which maintain tolerance to self - antigen. some strategies, derived from these mechanisms has been proved to be encouraged in suppression of allograft rejection
二十世紀五十年代以來，器官移植的進展使同種異體器官移植成為治療多種器官終末期疾病的有效手段。盡管目前免疫抑制方案非常有效，但免疫耐受仍是移植免疫學家和外科醫生關注的課題。有多個機制使免疫系統對自身抗原保持耐受，如：克隆清除、忽略、失能、免疫調節。Topical agents are often unable to fully control severe atopic dermatitis, but while systemic therapies can be effective, continuous use of such agents is limited by end - organ toxicities
局部藥物通常不能完全控制重度特應性皮炎的病情，而系統性治療是有效的，但是終末器官的毒性限制了這些藥物的持續應用。
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