The purposes of the present study were to investigate ( 1 ) the hemodynamic effects of agmatine in anaesthetized dahl salt - sensitive ( ds ) hypertensive and dahl salt - resistant ( dr ) rats ; ( 2 ) the effect of agmatine on vascular tension in the isolated aortic artery of rats and the underlying receptor mechanism ; ( 3 ) the effects of local injection of agmatine on femoral, renal, and mesenteric vascular beds by constant flow perfusion method ; ( 4 ) the effect of agmatine on l - type calcium current ( / ca - t ) in rat ventricular myocytes with whole - cell configuration of the patch - clamp technique ; ( 5 ) the effects of agmatine on free intracellular calcium concentration ( ca2 + d of isolated rat ventricular myocytes
( 3 )採用後肢、腎臟和腸系膜動脈在體恆流灌注法,觀察向灌流環路中直接注射
胍丁
胺的血管效應。 ( 4 )應用全細胞膜片箝技術,觀察
胍丁
胺對大鼠心室肌細胞l -型鈣通道電流( i _ ( ca - l ) )的影響。 ( 5 )用fluo3 - am負載分離的大鼠心室肌細胞后,由激光共聚焦法測定單個心室肌細胞[ ca ~ ( 2 + ) ] _ i的熒光強度,觀察
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胺對分離大鼠心室肌細胞內游離鈣濃度( [ ca ~ ( 2 + ) ] _ i )的影響。
Determination of the content of 1 - cyanoguanidine of the metformin hydrochloride sustained - release tablets by hplc
法測定鹽酸二甲雙
胍緩釋片中雜質雙氰
胺含量
Slimming drugs commonly used appetite inhibitors, these drugs through the hypothalamus to influence diet and the central body of the excitement and inhibition play appetite, patients readily accept diet therapy, such as amphetamine - type ; metandienone increase metabolism, is to promote metabolism, so the body ' s adipose tissue accumulation by gradually eliminate, such as thyroid hormone ; biguanides hypoglycemic agents, the drugs in the treatment of diabetes, patients can cause loss of appetite, this is the side effects, but the drug has reduced the cumulative amount of fat and suppress appetite, delaying or reducing gastrointestinal absorption of the sugar, increase fecal fat and he substances excreted, speaking on obesity and is beneficial side
常用減肥藥物有食慾抑制劑,這類藥物是通過對下丘腦飲食中樞發生影響以及對全身的興奮而起到食慾抑制作用,使病人易於接受飲食療法,如苯丙
胺類;增加代謝類藥,是促進機體代謝,使體內蓄積的脂肪組織逐漸消除,如甲狀腺激素;雙
胍類降血糖藥,本類藥物在治療糖尿病時,可引起病人食欲不振,本是副作用,但此藥有降低脂肪積存量的作用,抑制食慾,延緩或減少胃腸道對糖分的吸收,增加糞便中脂肪及其他物質的排泄,對肥胖者來說恰是有利的一面。
Differential responses of regional vascular beds to local injection of agmatine in rats
區域性血管床對局部注射
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胺的不同反應
Action of agmatine on tension of isolated aortic artery and its receptor mechanism in rats
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胺對離體大鼠主動脈張力的影響及其受體機制
However, little is known about cellular mechanism underlying the cardiovascular actions of agmatine
然而,有關
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胺心血管作用的細胞機制,至今尚未見報道。
It has been known that agmatine was widely distributed in cardiovascular system of mammalian tissues, suggesting that agmatine could act on cardiovascular system
已知心血管系統能合成和貯存
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胺,從而提示其可能對心血管系統有作用。
In 1994, li et al isolated agmatine from cow brain. like clonidine, agmatine is an endogenous agonist at imidazoline receptors ( ir ) and a noncatecholamine ligand at ( ai - adrenergic receptors ( ( x2 - ar )
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胺( agmatine )是1994年li等從牛腦中分離純化的一種內源性可樂定置換物質( clonidinedisplacingsubstance , cds ) ,它可能作為一種新型的神經遞質或調質。
Electrophysiological effects of agmatine on guinea pig papillary muscles in vitro li xiaotao ; he ruirong
胍基丁
胺在離體豚鼠乳頭肌的電生理效應
< uk > perfluoroguanidine can be prepared by the direct fluorination of dry ammeline with 5 % fluorine at about - 16. < / uk >
< uk >全氟胍可以由於的三聚氰酰胺,用5的氟在約16直接進行氟化制得。 < / uk >