胚前期發育 的英文怎麼說
中文拼音 [pēiqiánqīfāyù]
胚前期發育
英文
pre-embryonic development-
Purpose embryonic stem cells ( escs ) which are from the inner cell mass ( icm ) of preimplantation blastula are pluripotent. neurons are considered as terminally differentiated cells that can not divide nor proliferate after injury
目的胚胎幹細胞( embryonicstemcells , escs )來源於著床前胚胎的囊胚期內細胞團( innercellmass , icm ) ,具有發育全能性。In the early neurula, cortactin staining signals were detected in the developing primodium of forebrain as early as 10. 5 hpf ( hours post fertilization ), at the same time the tailbud areas were highly stained too. later, the staining was concentrating in the developing neural rod while paraxial mesoderm derivatives were not stained
在早期神經胚,神經系統中的前腦原基最先出現染色,並保持頭尾兩端處染色最強的圖式,隨后,染色集中分佈在發育中的神經龍骨中,但近軸中胚層細胞沒有染色。Using the hprt gene as a positive control, our result suggested that both the testis tissue and the male embryos from which sry transcription can be detected failed to yield any positive results of xist. female embryos at the pronucleus stage and 2 - cell failed to produce any positive result of sry and xist too. while since the 4 - cells period, xist is constantly transcribed until blastocyst stages
然後利用實驗一確定的pcr條件,以hprt為陽性對照,用巢式rt - pcr對小鼠早期胚胎進行xist基因的轉錄分析,結果發現,轉錄sry基因的睪丸組織以及雄性胚胎,從受精卵發育到囊胚的過程中,基本上不轉錄xist基因;不轉錄sry基因的雌性卵母細胞和雌性胚胎,從出現原核開始,到發育至2 -細胞期的過程中, xist基因一直不轉錄,但是,從4 -細胞期開始,一直到孵化前囊胚階段,雌性胚胎都轉錄xist基因。Human bone morphogenetic protein 3 is a member of tgf - b superfamily. lt can induce the differentiation of cartilage and bone tissue in mesenchymal cell. and is important to bone self - repairment and bone development during embryo morphogenesis. in addition, some other biological activities of hbmp - 3 have also been found. such as inducing development of embryo and stimulating differentiation of neural and blood cells. therefore, there is a great prospect in the use of hbmp - 3. there is trace content of hbmp - 3 in human body. it has been expressed in the expression system of eukaryotes and prokaryotes respectively, but its application is restricted because of defects in the process and modification after translation in prokaryotic cells and higher costs and lower yields existed in eukaryotic expression system
人骨形成蛋白3 ( hbmp - 3 )屬于tgf -超家族的一員,可以誘導間充質細胞分化為軟骨和骨,在胚胎時期骨骼發育和骨再生修復中起著重要的作用,而且對胚胎發育過程中中胚層的誘導和分化、造血組織的發育以及神經系統的發育和修復等都起著重要作用,因而hbmp - 3有廣闊的市場前景。它在人體內含量極微,盡管研究人員已經在原核細胞和真核細胞表達系統中分別進行了表達,但是由於原核表達系統缺乏翻譯后的加工修飾,真核表達系統存在成本高、產量低等特點,限制了其在臨床上的應用。Obesity, pre - diabetes and diabetes can affect ejaculation, sperm production, ovulation, miscarriage rates and increase fetal malformation rates
肥胖、糖尿病前期和糖尿病都能影響射精、精子產生、排卵、流產幾率和增加胚胎發育不良的機會。Although earlier attempts at retina transplantation using embryonic stem cells failed, the researchers say that by using stem cells at a later stage of development, they were able to repair damaged retinas in the mice
盡管以前嘗試使用胚胎幹細胞進行視網膜移植失敗了,研究人員稱通過使用發育後期的幹細胞,他們修復了小鼠受損的視網膜。“ we worked on the theory that cells at a later stage of development might have a higher probability of success upon transplantation ” says researcher robin ali of the university college london institute of ophthalmology in a news release
盡管以前嘗試使用胚胎幹細胞進行視網膜移植失敗了,研究人員稱通過使用發育後期的幹細胞,他們修復了小鼠受損的視網膜。There was no significant difference between the fusion rates of reconstructed embryos. the cleavage rate of embryos reconstructed with c57bl / 6j oocytes was significant high than that of kunming albino, but the former only developed to 4 - cell stage ; the later could develop to blastocyts. it is implied that the oocytes of inbred mouse cannot support the long - term development of kunming es cell
兩種重構胚的融合率之間沒有顯著差異( p 0 . 05 ) , c57bl 6j重構胚的卵裂率( 60 . 5 )明顯高於昆明白小鼠( 33 . 7 ) ,但是前者只發育到4細胞期,而後者可以發育到桑椹期和囊胚期( 2 . 3 ) 。The study of human embryos cultured in vitro indicated that the survival rate and viability of embryos cultured in vitro is much lower than those in vivo
對在體外培養的人胚胎的觀察發現,大約有50的人胚在發育至胚泡期之前停止發育。Es cells are the cells derived from the inner cells mass ( icm ). they are capable of differentiating in vitro into multiple cells types under the stimulation of right signals
Es細胞來源於著床前囊胚期內細胞團( innercellmass , icm ) ,具有發育全能性。分享友人