能耐受的 的英文怎麼說
中文拼音 [néngnàishòude]
能耐受的
英文
tolerant-
In view of the common property of dendritic cells and complement, namely their ability to link innate and acquired immunity, and with no reports, to date, addressing the direct effects of complement on the biological functions of dendritic cells, we decided to study the interaction between the complement system and dendritic cells
本研究的完成有助於在免疫應答的調控機制方面獲得新的認識,並對補體和dc在連接天然免疫和獲得性免疫之間的作用及相互關系能有更全面的理解,為進一步從新的角度和思路深入研究dc在抗原特異性免疫應答與免疫耐受中的作用及其機制奠定基礎。On the other hand, there is substanial evidences tha dcs mediate tolerane. the gm - csf - stbolated mouse bone mwderived mhc class ii + dc progendors tha are deficient in cell surface erpression of the costbolatory molecules b7 - l and b7 - 2 can induce alloanginspecific t ceil anergy in vbo. systendc adchstraion of these donor - derived dc progendors to recipients intravenously 7 days before transplantation prolonged the median graft survival tane from 9. 5 days to 22 days wbout additional twnosuppressions in a mouse cardinc twlanation model
1995年, lul等報道表面缺乏共刺激分子,特別是缺乏cd80 ( b7 - 1 )和cd86 ( b7 - 2 )的未成熟型dc能在體外誘導同種抗原特異性的t細胞無能,而對dc的適當處理能夠使未成熟型dc潛在的耐受原性得以放大和增強,使得dc在誘導免疫耐受中具有相當重要的作用及潛在的應用價值。Transplantation has been developed to an effctive strategy for treatment of end stage diseases of multiple organs since 1950 ' s. despite success of current immunosuppressive drugs, transplantation immunologists and surgeons are still seeking to achieve tolerance to allograft. there are several different mechanisms such as clonal deletion, anergy, neglect, immuno regulation. which maintain tolerance to self - antigen. some strategies, derived from these mechanisms has been proved to be encouraged in suppression of allograft rejection
二十世紀五十年代以來,器官移植的進展使同種異體器官移植成為治療多種器官終末期疾病的有效手段。盡管目前免疫抑制方案非常有效,但免疫耐受仍是移植免疫學家和外科醫生關注的課題。有多個機制使免疫系統對自身抗原保持耐受,如:克隆清除、忽略、失能、免疫調節。A buffer system resists a change in ph.
緩沖系統對pH的變化是有耐受能力的。The sodium silicate makes the cork stick to the mold surface and also helps to withstand the charring action of the molten lead alloy.
硅酸鈉能使軟木粉粘結在模具表面,而且還有助於軟木粉耐受熔融鉛合金的碳化作用。Nothing less than the complaisance of a courtier could have borne without anger such treatment ; but sir william s good breeding carried him through it all ; and though he begged leave to be positive as to the truth of his information, he listened to all their impertinence with the most forbearing courtesy
遇到這種情形,只有象朝廷大臣那樣能夠逆來順受的人,才不會生氣,好在威廉爵士頗有素養,竟沒有把它當一回事,雖然他要求她們相信他說的是實話,可是他卻使出了極大的忍耐功夫,滿有禮貌地聽著她們無理的談吐。The resistance of n / med tuberculosis bacili is stronger, ability catch a cold catch a cold is cold, although cold to freezing point, still cannot exterminate it, achieve liquid air even ( namely 0 celsius 189 degrees of ), in that way low temperature, it also ability suffers a few hours
結核桿菌的反抗力是比較強的,能耐受嚴寒,即使冷到冰點,還不能殺滅它,甚至達到液體空氣(即零下攝氏度189度) ,那樣的低溫,它也能耐受幾小時。Depending on their level of mauriy, dcs express proininnt 1evels of mhc class l and class ii molecules, as well as costdrilatory molecules such as cd40, cd80, and cd86. wl studies show them to be responsible pranarily for sensitto naive t cells in their first empsure to anigen
但是,近年來的研究表明, dc是一類異質性細胞群體,具有不同的亞群和不同的功能狀態,不但在增強免疫反應上具有特別重要的作用,也具有誘導特異性的免疫耐受的作用。Effects of diverse environmental factors on the growth rate ( od4oo ) and nitrogenase activity ( ara ) of the strain w12 hi nitrogen - free culture were investigated in our experiments. the results implied that the strain w12 could easily adapt to different cultural conditions : it could use various carbon sources ( especially glucose, sucrose, malic acid, mannitol ), propagate quickly and fix nitrogen at a temperature range of 15 ? to 40 ? and at 25 - 35 ? for optimum, at a ph range of 4 to 8. 5, at a saline concentration range of 0. 01 % to 1. 5 % ; low nlv " concentration had little effect on its nitrogenase activity. ara could also be detected when it grow in the culture media with 5mmol / l ntv "
W12菌株對環境因子的適應性研究:無氮培養條件下,測定溫度、碳源、酸堿度、滲透壓對w12生長及固氮能力的影響,結果表明,在15 - 40下均能生長並表達固氮酶活性,其最適生長及固氮的溫度為25 - 35 ;能利用葡萄糖、蔗糖、蘋果酸、甘露醇等多種碳源生長並固氮,當培養基中同時存在蔗糖和蘋果酸時,細菌生長和固氮活性最強;在偏酸和偏堿的條件下( ph4 . 5 - 8 . 5 )均能保持較強的生長勢和較高的固氮酶活性,並能通過調節自身代謝平衡並適應環境的酸、堿性變化,使培養液趨于中性:能耐受較高的滲透壓,培養液中卜、 5 naci濃度對其生長和固氮酶活性影響不大,當naci濃度升至2時,菌株的生長勢及固氮酶活性才有所下降:低濃度的鉸對其固氮酶活性影響不大,在0Although, ingeneral, the treatment is well tolerated, certain side effects canoccur and have to be taken into consideration - hypothyroidism, highblood pressure and fatigue
大體來說,患者都能耐受給項治療,也存在某些副作用,需要注意的是甲狀腺功能減退、高血壓以及疲勞。The maximum power : what the card can endure, be equal to precision alumina ceramic ( alumina 95 % ). high - power laser can make the card display bright green
最大功率:可耐受精密陶瓷所能耐受的大功率激光,較大功率的紅外激光可轉換為明亮的綠光。The shorter the interval between the two pulses of the current wave, the fewer strikes the varistors can endure. at the same time, the dc ljima changes fast - slowly - fast alone with the experiment continuing. microstructual disorder, such as variations in the height of the electrostatic potential at grain boundaries and electrode protrusions into the zinc oxide varistors, causes substantial temperature rise in a microscopic region around the defect and is the source for failure
雷電的多重閃擊對雷電過電壓保護器件的影響更加嚴重,本文首次採用不同間歇時間雙脈沖電流沖擊對氧化鋅電阻進行了多次試驗,試驗表明:氧化鋅電阻在雙脈沖電流沖擊下更容易出現老化破壞現象,間歇時間越短,電阻能耐受的沖擊次數越少;此外,直流u _ ( 1ma )值隨沖擊次數的增加具有快一慢一快的下降過程。At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
但是,學者們發現這一療法存在著如下的缺陷:單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用,且有誘導免疫耐受的潛在危險,有時反而會促進腫瘤的生長;事先需對患者的hla單倍型進行鑒定,以確定ctl表位與hla單倍型是否匹配,目前尚缺乏能與所有hla單倍型相匹配的ctl表位,從而限制了這一療法的應用;這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞,但對腫瘤細胞的殺傷能力較弱:這種l表位抗原肽缺乏cd4汀h細胞相關的表位,因此,不能誘導有效的th細胞免疫應答。Purpose : this study was designed to determine the potential of the pretreatment with fty720 ( fty ) to prolong cardiac allograft survival and explore its operational mechanism
目的:為進一步探討fty720的作用機制,探索利用該藥誘導移植免疫耐受的可能途徑,我們進行了本研究。Thus, it will help elucidate the development, self tolerance of self autoreactive b lymphocyte repetoire to investigate the generation of naa. researches on the function of naa will help clarify the significance of naa ' s existence. the exploration of biological nature, encoded gene and the difference or relation between naa and pathological autoantibody will shed much light on the pathological mechanism and treament of autoimmune disease
因此,對naa產生機理的揭示將有助於回答免疫學b細胞產生、發育以及自身耐受的問題;對naa功能的研究有助於進一步明確naa對機體的意義;對naa的特性、編碼基因、與病理性自身抗體界限和關系的研究可能對自身第四軍醫大學碩士學位論文免疫疾病的發病機制和治療提供有益的線索。The researchers note that further studies are needed in patients not pretreated with antiplatelet agents, including those intolerant or allergic to aspirin or clopidogrel, and those with aspirin and / or clopidogrel resistance
研究者指出,還需進一步對未使用抗血小板藥物的患者(包括不能耐受阿司匹林或氯吡格雷者、或對其過敏者,以及存在阿司匹林和/或氯吡格雷抵抗者)進行研究。This tester is used to determine the isolation character of the shoe material
本機在測試鞋底或絕緣鞋材所能承受的電壓值,以?解其耐電壓程度。Elderly patients often cannot tolerate standard treatment including chemotherapy and radiation therapy, particularly if they have other existing medical conditions
年老的患者通常不能耐受標準治療方法包括化療和放療,尤其是如果他們患有其他疾病的條件下。A novel catheter technique for patching holes in the heart may make it possible for many patients to avoid surgery altogether and others to regain enough strength to safely undergo surgical repair at a later date, according to a study reported at the 30th annual scientific sessions of the society for cardiovascular angiography and interventions, may 9 - 12, 2007, in orlando, fl
2007年5月9日至12日在佛羅里達州奧蘭多市舉行心血管造影及介入聯合會第30界年會,大會的一項研究報告揭示,一項新的修補心臟缺損的介入導管技術可以使許多患者完全免於外科手術,也可以使部分過于虛弱不能耐受手術的患者恢復足夠的身體耐受性再來安全地接受隨后的手術。In a study published january 30 in the journal geophysical research letters, dartnell ' s team found that even the most radiation - tolerant earthly bacteria would survive only 18, 000 years at the surface
在1 . 30發表的一份研究中,達奈爾的團隊發現,最能耐受宇宙射線的地球細菌也只能在地表存活18000年分享友人