腫瘤抑制劑 的英文怎麼說

中文拼音 [zhǒngliúyìzhìjì]
腫瘤抑制劑 英文
tumor inhibitor
  • 腫 : Ⅰ名詞（隆起處） swelling Ⅱ動詞（突起） swell; be swollen
  • 瘤 : 名詞（瘤子） tumour
  • 抑 : Ⅰ動詞（向下按; 壓制） restrain; repress; curb Ⅱ連詞[書面語]1 （表示抉擇） or 2 （表示轉折） but3 ...
  • 制 : Ⅰ動詞1 （製造） make; manufacture 2 （擬訂; 規定） draw up; establish 3 （用強力約束; 限定; 管束...
  • 劑 : Ⅰ名詞1 （藥劑; 制劑） a pharmaceutical or other chemical preparation 2 （某些有化學作用的物品） a...
  • 腫瘤 : tumour; core （綿羊體內的）; neoplasm; phyma
  • 抑制 : 1 （控制） restrain; control; check; hold up; curb; stop; repress; bridle; choke; prehension; sup...
  1. Protein kinase a is camp - dependent kinase, one of the most important signal transduction pathways, plays a pivotal role in growth, differentiation, tumor occur, cell cycle control, etc. pka activators such as camp, 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes, also in xenopus oocytes

    蛋白激酶a （ proteinkinasea ， pka ）是依賴于camp的絲蘇氨酸蛋白激酶，是重要的信號傳導途徑之一，廣泛參與許多生命過程，包括生長、分化、腫瘤發生、細胞凋亡、細胞周期調控等。以小鼠卵母細胞為實驗對象，給予pka激動劑camp 、 8 - br - camp或磷酸二酯酶抑制劑imbx （ isomethylbutylxanthine ）均可抑制小鼠卵母細胞的胚泡破裂及減數分裂成熟。
  2. Mdr1 express product p - glycoprotein was detected by immunocytochemical method and flowcytometry. the cytotoxicity and multidrug resistance reversion effect of tea polyphenol was examined by mtt assay in mcf - 7 and mcf - 7 adr carcinoma cell lines, and compared with pgp inhibitor quinidine. the pgp expression of mcf - 7 adr was strongly positive, the positive rate was 15 % ; the pgp expression of mcf - 7 was negative, the positive rate was 1. 8 %. ic50 of tea polyphenol to mcf - 7 and mcf - 7 adr is 115. 2g ml and 207. 6g ml respectively. ic50 of quinidine to mcf - 7 and mcf - 7 adr is 129. 8mol l 42. 1g ml and 94. 1mol l 30. 5g ml respectively. tea polyphenol and quinidine changed little toxicity of adriamycin to mcf - 7, but tea polyphenol and quinidine improved the sensitivity of mcf - 7adr to adriamycin significantly. immunocytochemistry and flow cytometry can detect p - glycoprotein expression level qualitatively and quantitatively. tea polyphenol is not only an anti - tumor agent, but also a multidrug resistant modulator similar as quinidine. tea polyphenol is advantageous for its little toxicity in tumor treatment

    用免疫組化法和流式細胞儀對腫瘤細胞系mcf - 7和mcf - 7 adr的p -糖蛋白表達水平進行定性定量研究。用噻唑藍比色法mtt研究茶多酚的細胞毒性及其對耐藥性的逆轉作用，並與pgp抑制劑奎尼定進行了比較。免疫組化法檢測p -糖蛋白表達水平， mcf - 7 adr呈強陽性，而mcf - 7呈陰性流式細胞儀定量檢測結果mcf - 7 adr細胞系細胞陽性率為15 % ， mcf - 7細胞系細胞陽性率為1 . 8 % 。
  3. Studies of the crystal structure of endostatin have shown a compact globular fold, with one face particularly rich in arginine residues acting as a heparin - binding epitope, this site was recently shown to be involved in the inhibition of induced angiogenesis. experimental studies show that recombinant endostatin specifically inhibits the proliferation of endothelial cells in a dosedependent fashion. recombinant endostatin from bacteria is largely insoluble, but still efficient in arresting tu mor growth after injection into mice. intermittent therapy with recombinant bacterially produced endostatin reduces several experimental tumors, including lewis lung carcinoma, to a dormant state. no sign of drug induced resistance has been reported and, in the original study, the treatment dormancy appeared to persist even when therapy was discontinued. sowe regard endostatin as a promising anti - tumor drug

    許多研究表明重組內皮抑素特異性抑制內皮細胞增殖，而且這種抑制作用呈劑量依賴性。細菌表達產物內皮抑素大部分以不溶形式存在，將這種混懸液注射治療老鼠仍可以抑制腫瘤生長。于小鼠皮下重復注射內皮抑素重組蛋白，幾乎完全抑制鼠lewis肺癌等多種腫瘤生長，並無耐藥性產生，即使中斷治療腫瘤也不再復發。
  4. Ganodermataceae is a new, important resource for antimicrobial, antitumor and a - glucosidase inhibitory agents

    靈芝真菌是重要的抗菌、抗腫瘤和-葡萄糖苷酶抑制劑的新菌源。
  5. In the study, four models were applied and used for prescreening antimicrobial, antitumor and the a - glucosidase inhibitory agents from medicinal fungi including filamentous fungi and macro fungi in fujian ; we studied the antimicrobial, antitumor and a - glucosidase inhibitory activities of three kinds of ganoderma sp. ; as well as we studied the a - glucosidase inhibitor from filamentous fungi w - 20 and its physical and chemical properties. there are abundant antimicrobial, antitumor and a - glucosidase inhibitory agents in filamentous fungi and macrofungi

    本課題以福建省的藥用真菌資源為對象，應用了抗菌、抗腫瘤和-葡萄糖苷酶抑制劑的體外篩選模型，進行了藥（食）用曲的絲狀真菌和大型真菌生物活性物質的篩選；對3種靈芝真菌的抗菌抗腫瘤、 -葡萄糖苷酶抑制活性，以及絲狀真菌w - 20抑制-葡萄糖苷酶的活性物質及其理化性質進行了初步研究，為我省藥用資源的開發利用打基礎。
  6. Studies of proton pump inhibitors and tumor resistance to antitumor drugs

    質子泵抑制劑與腫瘤耐藥研究
  7. Advance in tumor angiogenesis inhibitors targeting vegf and its receptors

    以血管內皮生長因子及其受體為靶點的腫瘤血管生成抑制劑的研究進展
  8. As a proteasome inhibitor, bortezomib has shown inhibition on cell proliferation, inducing cell apoptosis, inhibition of cell adhension and inhibition of tumor angiogenesis for multiple myeloma cells

    摘要硼替佐米作為一種蛋白酶抑制劑，對多發性骨髓瘤細胞表現出抑制細胞生長、誘導腫瘤細胞凋亡、抑制細胞粘附、抑制腫瘤血管生成等作用，同時對血液系統其他惡性腫瘤具有顯著的作用。
  9. Sleep / waking cycle is a complex network modulation and many factors such as interleukin - 1 ( il - 1 ), tumor necrosis factor ( tnf ), growth hormone releasing hormone ( ghrh ), vasoactive intestina polypeptide ( vip ) and many conventional neurotransmitters such as serotonin ( 5 - ht ), acetylcholine ( ach ), norepinephrine ( ne ), dopamine ( da ) and gamma - aminobutyric acid ( gaba ) were involved in it. recent evidence has shown that no synthesized in neurons in several areas of the brain can induce the release of neurotransmitters. in the rat central nervous system, the anatomical distribution of nos - containing neurons is now well established, and it was reported that nos is co - localized with neurotransmitters well known for their involvement in sleep mechanisms, i. e. 5 - ht, ach, da and gaba

    鄭州大學2003屆碩士畢業論文gaba受體激動劑消除no合成酶抑制劑對大鼠睡/醒周期的影響睡/醒周期的形成是一個復雜的網路調控的結果，體內許多因子都參與了這一調控網路，這些因子如白介素一1 （ il一1 ） 、腫瘤壞死因子（ tnf ） 、生長激素釋放激素（ ghrh ） 、血管活性腸膚（ vip ）以及經典的神經遞質如5一輕色氨（ 5一ht ） 、乙酞膽堿（ ach ） 、去甲腎上腺素（ ne ） 、多巴胺（ da ）和卜氨基丁酸（ gaba ）等，它們在睡眠的發生和調節中也發揮著重要作用。
  10. With the use of immunosuppressive drugs that efficiently control acute rejection, organ transplantation has achieved impressive development. nevertheless, clinical transplantation still thces some important problems : lilblong immunosuppression is associated with toxicity, oppottunistic infections and a high incidence of cancer

    免疫抑制劑的應用使器官移植獲得了很大的發展，然而，終身免疫抑制所帶來的毒性、機會感染及腫瘤的高發病率成為臨床器官移植所面臨的重要問題。
  11. It is well known that tumor necrosis factor a ( tnfa ) can play very different character in defence mechnism of body and pathologic injury, in which it can inhibit or kill tumor cell, and induce inflammation against infection ; on the other hand, tnfa can be as a very important mediator to cause some serious pathologic processes such as septic shock, gvhr and some autoimmune diseases

    腫瘤壞死因子（ tumornecrosisfactor ， tnf ）具有對某些惡性腫瘤的抑制或殺傷作用，也是致內毒素性休克、急性移植物抗宿主病及一些自身免疫病的重要效應因子，因此tnf的改造和tnf拮抗劑的研究受到各國學者的重視。
  12. Conclusion with the development of molecular biology and the exploitation of antiangiogenesis, it is of great importance for glioma which is characterized by vascular proliferation to study deeply on the antiangiogenesis therapy

    結論隨著分子生物學的發展，腫瘤血管抑制劑的不斷開發和研究，對于腦膠質瘤這一血管增生極為突出的腫瘤，深入研究抗血管治療具有重要意義。
  13. The research fields covers chemical synthesizing, microbiology ， biotechnology, the extraction separation and pharmaceutics and the products aiming to cure people ' s disease are related to anti tumor, cardiovascular system, anti - infective, antiphrastic, endocrine system, immunosuppression, anti depress, etc

    研發領域涵蓋化學合成、微生物發酵、生物技術、天然植物提取及制劑開發等多個方面，產品治療領域涉及抗腫瘤、心血管系統、抗感染、抗寄生蟲、內分泌調節、免疫抑制、抗抑鬱等。
  14. Two angiogenesis inhibitors have been developed that have a broad spectrum of anticancer activity, yet virtually no side effects

    目前，已有兩種具有廣譜抗腫瘤活性且無明顯副作用的血管生成抑制劑面世。
  15. In studies of mice, the researchers found that angiogenesis inhibitors decreased the diameters of tumor blood vessels and made them less leaky, so they began to resemble normal vessels

    研究人員在小鼠的身上發現，血管新生抑制劑會使腫瘤血管的管徑縮小，讓這些血管比較不那麼容易滲漏，而變得更像正常的血管。
  16. Treatment of rheumatoid arthritis by tumor necrosis factor inhibitor

    腫瘤壞死因子抑制劑治療類風濕關節炎
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