腸泌酸素 的英文怎麼說
中文拼音 [chángbìsuānsù]
腸泌酸素
英文
enterooxyntin-
Background : ghrelin is a 28 - amino acid endogenous peptide recently identified in the secretory granules of x / a - like cells in the rat stomach, which can act on the growth hormone secretagogue receptor to accelerate the secretion of growth hormone. it was identified that ghrelin - immunoreactive cell and its receptor localize in areas of brain, such as hypothalamus ( pvn, arc ), hippocampus, adenohypophysis and so on. motilin is a 22 - amino acid peptide secreted from the upper part of the small intestine, which regulates the interdigestive motility of gastric
背景資料： ghrelin是新發現的由28個氨基酸組成的內源性腦腸肽，由胃部泌酸腺x / a樣內分泌細胞分泌， ghrelin免疫活性神經元及其受體在中樞神經系統中如下丘腦室旁核（ paraventricularneucleus ， pvn ） 、弓狀核（ arcuatenucleus ， arc ） 、海馬區及腺垂體等均有不同濃度的分佈，可與生長素促泌物受體（ growthhormonesecretagoguereceptor ， ghsr ）結合促進生長素（ growthhormone ， gh ）分泌。Moreover, human ghrelin receptor exhibits a remarkable 50 % overall identity with human motilin receptor, therefore it was named as " raotilin - related peptide ". anatomical evidence showed that there are ascending and descending neuronal projections between pvn, bma and lower brain stem ( nts, dmx ), which participate in the regulation of gastric acid secretion and gastrointestinal motility. moreover, pvn is the center of appetite regulatory web
Pvn與低位腦干（延髓迷走復合體）及邊緣系統之間有密切的纖維聯系，且含有多種神經肽，參與胃酸分泌，胃腸活動等多種生理機能的調節，是影響消化道功能與攝食行為的重要中樞部分， pvn內胃動素可促進胃排空和攝食，而新發現的ghrelin /胃動素相關肽是否參與此核區對胃運動的調節機制及其可能的神經通路尚不明了。Lymphotoxin ( lt ) is a kind of pleiotropic lymphocyte - secreted cytokine which mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. in order to increase the antitumor activity of lymphotoxin and reduce its side effects, the recombinant plasmid pet36b - lt 27 was constructed to express soluble fusion protein cbd - lt 27. the active form of lt 27 could be collected directly with several simple steps by three kind of components on the expressed fusion protein
本研究通過構建表達n端缺失27個氨基酸的淋巴毒素融合蛋白的重組質粒，在大腸桿菌中實現融合蛋白的可溶及分泌表達，同時利用表達載體上的幾種特殊序列經簡單的分離純化步驟直接獲得大量的有生物活性的淋巴毒素缺失體lt 27 ，為尋找一種高抗腫瘤活性、低臨床毒副作用的生物抗癌藥物進行了有效的探索。It was recognized as a brain - gut peptide since the peptide and its receptor exist in the central nervous system. previously, we demonstrated that motilin and motilides activates cells in paraventricular nuclei ( pvn ) reflected by increased gastric motility and induction of the immediate early gene c - fos in conscious rat, which suggests central motilin participates in the regulation of gastric motility. it was reported in 2001 that ghrelin is an appetite - stimu latory signal from stomach with structural resemblance to motilin
胃動素（ motilin ， mt ）是由小腸上段粘膜內分泌細胞合成並分泌的22個氨基酸組成的腦腸肽，調節消化間期胃運動， pvn內給予胃動素和胃動內酯（ motilides ）可增強清醒大鼠胃運動，中樞微量注射胃動素可誘導pvn中立即早期基因c - fos的表達，提示中樞胃動素參與胃運動的調控，人ghrelin和胃動素之間有36的相似性，而且二者的受體之間有50的相似性，因而有人稱ghrelin為「胃動素相關肽」 。分享友人