The barnidipine hydrochloride were prepared via cyclocondensation from m - nitrobenzaldehyde, methyl acetoacetate and anmmonium bicarbonate, hydrolysis, esterification with opticaliy ( s ) - n - benzyl - 3 - py - rrolidinol, recrystallisation and salification
摘要研究了以碳酸
氫銨,間硝
基苯甲醛和乙酰乙酸甲酯為原料,經縮合、部分水解,再與( s ) - n -
芐基3 -羥
基吡咯烷經酯化、分步重結晶、成鹽得到鹽酸巴尼地平的工藝路線。
Methods 3, 3 - bis ( dibenzyloxyphosphoiyl ) propionic acid ( 5 ) and ( 6 ) were synthesized from tetraethyl methylene bisphosphonate via hydrolysis, chlorination of the acid, esterification, condensation, then 3, 3 - bis ( dibenzyloxyphosphoryl ) propanol ( 6 ) was obtained via selective reduction of ( 5 )
方法以亞甲
基偕二膦酸四乙酯( 1 ) ?原料經水解、氯膦酰化、酯化、縮合得3 , 3二(二
芐氧膦酰
基)丙酸( 5 ) ,隨后選擇性硼
氫化還原得3 , 3二(二
芐氧膦酰
基)丙醇( 6 ) 。
Effects of 6 - benzyladenine and abscisic acid on the photosynthetic function and hydrogen peroxide content in tobacco leaves of different development phase
芐基腺嘌呤和脫落酸對不同發育階段煙草葉片光合功能及過氧化氫水平的調控