蛋白酶體 的英文怎麼說
中文拼音 [dànbáitǐ]
蛋白酶體
英文
proteasomes overview-
Some extracellular proenzymes may be activated by secreted lysosomal proteinases.
有些細胞外酶原能被分泌的溶酶體蛋白酶所激活。They alter the way it cleaves amyloid precursor protein
它們改變了這個酶切割澱粉樣蛋白前體的方式。Arginine feeding experiment showed that nitrogen metabolism in the s. tenebraius was obviously affected by arginine through two possible ways : ( l ) pronase activity in vitro could be influnced by arginine, as a result, the catabolism of nitrogen - containing macro - molecule was promoted and the nitrogen element in the broth was increased. ( 2 ) arginine could be transformed into glutamic acid, so that the biosynthesis of apramycin was promoted
因而我們認為gln可能是安普黴素生物合成氮元素的供體。 arg添加實驗結果表明, arg可能通過兩種途徑影響黑暗鏈黴菌體內的氮代謝: ( 1 ) arg可能影響胞外蛋白酶的活性,進而促進含氮大分子物質的分解代謝,補充發酵過程中的氮素來源。Antibodies were used in the macrophage system to inhibit cathepsin d.
巨噬細胞系統中使用了抗體來抑制組織蛋白酶D。Antibodies were used in the macrophage system to inhibit cathepsin d
巨噬細胞系統中使用了抗體來抑制組織蛋白酶d 。The high homology genes are not found in all genes known. but the putative conserved domains of peptidase have been detected. in the domains the homology comparing with callus gallus cathepsin b cdna is 90 %
Ncbi檢索未見同源性高的基因序列,但發現含有典型的肽酶結構域,編碼蛋白與組織蛋白酶b結構域部分一致性高達90 ,其具體功能有待于進一步驗證。Among the genes, there were genes directly related to liver regeneration : fetuin, cathepsin ; close related to liver function : cytoplamic aspartate aminotranferase, gutathion sulfur transferase ; related to substance and energy metabolism : atp synthetase, ribosomal protein, and related to stress response : haptoglobin, transferrin
這些基因中有和肝再生有直接關系的如:胎球蛋白、組織蛋白酶;和肝臟功能密切相關的如:胞質天冬氨酸轉氨酶、谷胱甘肽硫轉移酶;與物質能量代謝有關的如: atp合成酶、核糖體蛋白;以及與急相反應有關的如:觸珠蛋白、轉鐵蛋白。Studies on the extraction and enzymology character of the crude protease from the body wall of holothurian
海參體壁粗蛋白酶的提取及酶學性質研究Abstract : numerous mushrooms are toxic to insects. to identify the chemicals involved in insecticidal activity, the toxicity of 14 species has b een studied for water solubility, thermolability, and dialysis. the data strongly s uggest that proteins are responsible for most of the insecticidal avtivity in mu shroom fruitbodies and may be a source of genes available for plant protection a gainst insects. among proteins, lectins and haemolysins are good insecticide candi dates because the toxicities are not affected by protease
文摘:許多蘑菇都對昆蟲表現出毒性.為了證實與殺蟲毒性有關的化合物,對14種蘑菇的毒性在水溶性、熱敏性和可透析性等方面進行了研究.研究數據表明,蛋白質對大多數蘑菇子實體的殺蟲活性起著重要作用,也許是一種可以用於植物抵抗害蟲的基因源.在數種蛋白質中,凝集素和溶血素因不受蛋白酶的影響而成為良好的殺蟲劑候選材料Numerous mushrooms are toxic to insects. to identify the chemicals involved in insecticidal activity, the toxicity of 14 species has b een studied for water solubility, thermolability, and dialysis. the data strongly s uggest that proteins are responsible for most of the insecticidal avtivity in mu shroom fruitbodies and may be a source of genes available for plant protection a gainst insects. among proteins, lectins and haemolysins are good insecticide candi dates because the toxicities are not affected by protease
許多蘑菇都對昆蟲表現出毒性.為了證實與殺蟲毒性有關的化合物,對14種蘑菇的毒性在水溶性、熱敏性和可透析性等方面進行了研究.研究數據表明,蛋白質對大多數蘑菇子實體的殺蟲活性起著重要作用,也許是一種可以用於植物抵抗害蟲的基因源.在數種蛋白質中,凝集素和溶血素因不受蛋白酶的影響而成為良好的殺蟲劑候選材料Study on the preparation of mucor protease by solid state fermentation
固體發酵制備毛霉蛋白酶的研究Almost one - third of all proteases can be classified as serine proteases, including complement subcomponent clr / cls, mannose - associated serine proteases ( masps ), ovochymase, spermadhesin, type ii transmembrane serine proteases ( ttsps ) etc. these proteins are involved in diverse biological processes, including developmental processes such as complement activation, ovulation, fertilization, tissue remodeling, cellular migration, cancer invasion and metastasis, intestinal digestion, embryogenesis, or organogenesis
絲氨酸蛋白酶( serineprotease )是機體最重要的酶分子之一,約占機體蛋白酶的三分之一,我們較熟知的絲氨酸蛋白酶就包括補體組分c1r c1s 、甘露糖結合絲氨酸蛋白酶、 ovochymase 、 spermadhesin和型跨膜絲氨酸蛋白酶等,它們參與了補體活化、排卵、授精、組織重建、細胞遷移、腫瘤浸潤和轉移、消化、胚胎發育、器官形成等多項生理功能。They are involved both in the production of mature proteins, acting as processing enzymes, and in the degradation of damaged or non - functional proteins [ 1 " 8l in plant plastids, proteases function in protein degradation seem to act to adjust the stoichiometry of subunits in supramolecular complexes, as well as to regulate the stoichiometry between different supramolecular complexes in response to environmental changes and process the nuclear - encoded preproteins in the stromal
除了在相關蛋白質轉錄和翻譯方面的調控外,專一降解這些蛋白的蛋白酶活性以及轉錄翻譯量的上升也會加強對這些蛋白質的降解。雖然到目前為止對光系統中蛋白酶的了解尚且不如對光系統中各種多肽以及蛋白色素復合體的了解,但是對類囊體和葉綠體中蛋白酶的研究已經進展到相當深度了。We have known that ir may activate ubiquitin - proteasom pathyway, our experiments focus on whether ubiquitin - proteasome pathway involves in the regulation of p27klpl during ir responses
我們知道ir能激活泛素化蛋白酶體途徑,那麼,泛素化蛋白酶體途徑是否參與ir誘導p27物』蛋白表達的調控Northern blot analysis showed that the mrna level of p27 k ' pl had no changes during ir responses ; the level of ubiquitinated p27klpl increased following 10gy - irradiation ; mg - 132 ( proteasome inhibitor ) inhibited the degradation of
我們通過初步的研究結果揭示: northem檢測結果表明ir對p27kip 『 mrna水平無明顯影響; ir誘導p27kip 』泛素化水平的增加;蛋白酶體抑制劑( mg一1It delivers the false ? folding peptides for presentation to proteasomes in normal cells, while in tumor cells it acts as main tumor - resistant antigen, inducing specific immune response. recent research found that grp94 also relates with cell cycles, differentiation and apoptosis
此外發現它還具有抗原提呈作用,在正常細胞中參與折疊錯誤蛋白到蛋白酶體的提呈;在腫瘤細胞中作為主要的腫瘤排斥抗原,引發針對該腫瘤細胞的特異性免疫反應。Effects of ubiquitin proteasome inhibitor induced endoplasmic reticulum stress and apoptosis on dopaminergic neuron
泛素蛋白酶體抑制劑誘發多巴胺能神經元內質網應激反應及其凋亡的作用However, the ubiquitylated substrate protein of these ubcs remains unknown, and the nature of the dna to which the repair factors bind is still unclear
這三種酶協同作用把泛素分子鏈作為標簽連接在目的蛋白上使之被26s蛋白酶體識別而降解。A defective protein, which binds polyubiquitin chain ( so - called " degrading label " ) through its - amino group of lys residue, is degraded in the proteasome
對于需要清除的蛋白質,通過其賴氨酸殘基側鏈-氨基連接多聚泛素鏈(降解標簽) ,繼而在蛋白酶體中被降解。By combining the information from the cdna sequences with functions of their homologs, we suggest that two kinds of hormones may play important roles during flower regeneration in a few ways : ( i ) proteolytic system of ubiqutin / 26s proteosome complex, ( ii ) actin - dependent vesicular cycling of auxin efflux carrier, ( iii ) regulating transcription of genes, ( iv ) phosphorylation and dephosphorylation
經過進一步的篩選,結合序列特徵和同源基因的功能信息對這些基因功能進行了初步分析。認為兩種外源激素可能通過泛素26s蛋白酶體復合體對調節蛋白的降解機制,生長素運輸載體肌動蛋白依賴的小泡運輸,基因轉錄調節,磷酸化和去磷酸化等調節過程誘導風信子花分生組織的再生。分享友人