融合抑制劑 的英文怎麼說

中文拼音 [rónggěyìzhìjì]
融合抑制劑 英文
fusion inhibitor
  • 融 : Ⅰ動詞1 （融化） melt; thaw 2 （融合; 調和） blend; fuse; be in harmony Ⅱ形容詞[書面語]1 （長遠; ...
  • 合 : 合量詞（容量單位） ge, a unit of dry measure for grain （=1 decilitre）
  • 抑 : Ⅰ動詞（向下按; 壓制） restrain; repress; curb Ⅱ連詞[書面語]1 （表示抉擇） or 2 （表示轉折） but3 ...
  • 制 : Ⅰ動詞1 （製造） make; manufacture 2 （擬訂; 規定） draw up; establish 3 （用強力約束; 限定; 管束...
  • 劑 : Ⅰ名詞1 （藥劑; 制劑） a pharmaceutical or other chemical preparation 2 （某些有化學作用的物品） a...
  • 融合 : fuse; mix together; anastomosing; reconcile; harmonize; compromise; amalgamate; coalesce; coalesc...
  • 抑制 : 1 （控制） restrain; control; check; hold up; curb; stop; repress; bridle; choke; prehension; sup...
  1. Materials and methods in our study, first the e. coli bl21 transformed already are cultivated in smaller scale and then the plasmids dna were extracted by the methods of alkaline lysis. the plasmids dna extraction were processed 37 overnight by the restrictive endo - incisase bam h i and xho i. the incision products were used to check the integrality and variability of the recombinant plasmids dna by 1 % agarose gel elec - trophoresis

    同預想結果基本吻合，大規模培養后純化得到的融合蛋白通過sds page顯示在52kda處有一條帶，而酶切后產物電泳結果顯示在26kda處分另有兩條蛋白帶，其中一條為gst ，另一條為hbrp ，基本符合實驗結果； hbrp對tpk活性的抑制呈劑量依賴性。
  2. The results were as follows : ( l ) the pre - incubation of pmr induced the exocytosis of the cortical granules ( cgs ) in the oocytes and reduced the quantity of the microvillus on the surface of oocytes ; ( 2 ) the matrix of cg might migrate to the surface of plasma membrane of oocytes after pmr pre - treatment. ( 3 ) incubation of zona - free hamster eggs with spermatozoa pretreated with pmr a ntiserum was associated with a dose - dependent significant reduction in the number of spermatozoa binding to the oolemma, compared with a contraband with a dose - dependent reduction of the fertilization rate and the penetration index. the results indicate that mr of human sperm plays an important role in sperm - oocyte fusion and oocyte activation

    結果顯示： （ 1 ）人精子mr能夠誘發去透明帶金黃地鼠卵母細胞中皮質顆粒的胞吐，並引起卵母細胞膜表面微絨毛形態和數量發生改變； （ 2 ）皮質顆粒胞吐后，其內容物可結合到卵膜表面； （ 3 ）抗mr抗血清預處理精子可抑制精子與卵子的結合與融合，使受精率、穿透指數和結合指數下降，並均有劑量依賴性。以上結果提示，人精子mr在受精過程中起重要作用，其主要作用可能是介導精-卵膜融合併促進卵母細胞的活化。
  3. Huctla4 - lg, " one of the most potent in1n1unosuppressive molecules, is a soluble recombinant fusion protein ( molecu1ar weight of approximately 92 kd ) consisting of the extracellular domain of human ctla - 4 and a fragment ( hinge and constant region ) of the fc portion of human iggl. it strongly adheres to the b7 molecule to block the cd28 - mediated costimulatory signal, resulting in inhibition of in vitro and in vivo immune response

    可溶性重組融合蛋白huctla4 - ig是一種新穎的免疫抑制劑，分子量約為92kd ，由人ctla - 4分子的胞膜外區與人igg1的fc段（鉸鏈區與恆定區）融合形成，能牢固地與b7分子結合，阻斷cd28介導的共刺激信號，導致免疫反應的抑制。
  4. This has historically been difficult to do as fusion inhibitors seek to disrupt a protein - protein interaction, which is tricky with a small molecule

    有史以來這一點都很難做到，因為融合抑制劑將破壞蛋白與蛋白的相互作用，這是小分子很難解決的問題。
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