轉錄延伸 的英文怎麼說
中文拼音 [zhuǎnlùyánshēn]
轉錄延伸
英文
transcription elongation-
A complete round of transcription involves the recruitment of polymerase and general transcription factors to the promoter, rna chain synthesis initiation and polymerase escape form the promoter, rna chain elongation, and finally termination with relaease of polymerase and nascent transcript from the dna template
一個完整的轉錄循環包括ranp和通用轉錄因子被招募至啟動子、 ran鏈合成的起始和ranp從啟動子的脫逸、 rna鏈的延伸以及伴隨ranp和新生rna鏈從dna模板釋放的轉錄終止等過程。Deletion of elp3 ( or other elp genes ) confers a set of phenotypes, some of which are associated with elongation defects
缺失yelp3 （或其它yelp ）可導致一系列表型，有的與轉錄延伸缺陷有關。Recent data have demonstrated that the tails of histones h3 and h4 greatly reduce the speed of transcript elongation through a nucelosome, and tail acetylation suppresses this effect
近來研究表明組蛋白尾部尤其是h3 、 h4四聚體的尾部強烈影響通過核小體的轉錄延伸速率，而尾部的乙酰化修飾可抑制這種影響。Recently, human elongator complexes have been isolated. the human complex is a fragile six - subunit complex that interacts with rnap ii and has hat activity directed against histone h3 and h4. depletion of elongator from hela nuclear extracts reduces the ability of these extracts to transcribe chromatin templates, providing biochemical support for the proposed role of elongator during transcript elongation in chromatin
近來人elongator也被分離，它也是個不穩定的六亞基復合物，可與rnap相互作用，具有hat活性，能乙酰化h3和h4 ，在hela細胞核抽提物中去除elongator可降低抽提物對染色質模板的轉錄延伸速率，提供了該復合物在染色質為模板的轉錄延伸中有功能的生化證據，但是上面的信息都來自體外研究。分享友人