The protein nucleic acid complexes were identified by autoradiography for 48 h. the psg5heo and igfbp - 6 promoter pcat vectors were transfected into cos - 7 cells with iipofectamin2000 ; these cos - 7 cells where treated with 1 jxm e2, with lonm tcdd and with both lonm tcdd and 1 jxm e2, individually ; the cat protein was examined by cat - els a. results : the congenital skeletal defects in fetal rats were induced with 10 - 15ug / kg tcdd or with 100 - 140 mg / kg ra with dosage - dependence effect. the igfbp - 6 mrna in rat calvaria tissue and mc - 3t3 - el cells were increased with tcdd and ( or ) ra, whereas the cell proliferation and igf - 2 mrna in mc - 3t3 - el cells was decreased in the status of e2
結果: tcdd在大鼠胚胎發育時期具有骨
骼致畸作用,骨
骼發育畸形包括:內翻足、
脊柱裂、顱面骨發育缺陷、無尾畸形等;隨著tcdd濃度的升高( 10一15林擴kg ) ,致畸率明顯上升( 14 . 7 %一24 . 6 % ) ; tcdd和ra聯合用藥可以增強對大鼠骨
骼發育的致畸效應; e :對成骨細胞內igf一2基因有正性調節作用,對igfbp一6基因有負性調節作用, tcdd可以抑制e :對細胞內xgf一2和igfbp一6的調節作用。
Removing a hundred tons of rock by hand while watching out for polar bears, the team recovered a large chunk of the skeleton, including portions of its estimated ten - foot - long ( three - meter ) skull, an almost complete forelimb, and sections of its dinner - plate - size verteb * *
在北極熊的監視下,用手搬開了數以百噸的石頭后,研究隊發現了一副巨大的骨
骼.包括約是英尺長(三米)的頭骨.幾乎完整的前肢和截面如大盤子般的
脊椎骨
Nogo - 66 receptor, ngr, cloned in 2001, is a leucine - rich - repeat glycophosphatidylinositol - anchored membrane protein which mediates nogo - 66 inhibition of axonal outgrowth. both the long acidic amino - terminal domain and the nogo - 66 fragment have strong neurite growth inhibitory activity suggest that nogo - a has at least two inhibitory domains. northern blot, in situ hybridization, western blot and immunocytochemistry analyses show that in addition to oligodendrocytes, nogo - a mrna and nogo - a protein are also expressed in neurons in developing and adult brain and spinal cord, nogo - a is also found in peripheral organs such as heart and testis
Northernblot 、原位雜交、 westernblot和免疫組化結果證明: nogo amrna和nogo蛋白除了在cns的寡突膠質細胞中表達,還表達于發育階段和成年的腦、
脊髓和外周神經節的某些神經元中,在外周組織如睪丸和心臟也有表達; nogoe在cns和pns以及多種外周組織中有廣泛分佈; nogo (除表達于腦和心臟外,在骨
骼肌中有較高表達。
An mtrp is a hyperirritable spot in a taut band of skeletal muscle fibers with characteristics related to central sensitization in the spinal cord
肌筋膜激痛點是骨
骼肌肉纖維里緊繃肌帶上的過度激活點,伴隨著與
脊髓里中樞性敏感化有相關聯的特徵。
The procedures for data processing and supplements of missing data are discussed. the skeletal and flesh subsystems and their geometric representations are established parametrically, which have functions of real - time manipulations and realistic appearance of human models
以參數化方法建立了人體模型骨
骼體系和體表體系及其幾何表達方法,對整個
脊柱、鎖關節和肩關節等處作了較復雜的建模,併兼顧了人體模型的實時操縱性和外觀真實性。
The orthopaedic and rehabilitation devices panel of the united states food and drug administration has recently recommended conditional approval of a medical device, which uses bmp - 2 to stimulate bone growth and shorten the healing period in spinal fusion operations
美國食品及藥物管理局( fda )的骨
骼和康復設施委員會最近有條件地核準使用一種醫療用品,該用品利用bmp - 2刺激新骨的生成,以加速
脊柱溶合術的治療及康復過程。
If necessary, the chiropractor will use x - rays, mri scans ; laboratory procedures to verify the alignment of the bony structures and to rule out other underlying pathological conditions
如有需要,
脊醫會要求病人作x光檢查,醫療化驗或掃描,以了解骨
骼的情況及排除其他病變的可能性
The conventional spinal fusion procedure, in which a bone graft ( harvested from patient s own pelvic bone ) is placed between vertebrae, aims to unite the adjacent vertebral bodies after several months of healing. fusion has been the traditional operation to alleviate neck and arm pain, a concept which is similar to that used in the welding in industry
醫生會從患者身上(一般為髖骨的部位)取出骨
骼作移植物,填補受損的椎間盤,待數個月後骨
骼細胞生長后,兩節
脊椎便會自動融合,病人的神經或
脊髓不再受壓,紓緩患者頸部及手臂痛楚。
Apoptosis of skeletal muscle cells following chronic compression and decompression of rats ' spinal cord injury
大鼠慢性脊髓受壓及減壓后骨骼肌細胞的凋亡