acidic domain 中文意思是什麼
acidic domain
解釋
酸性結構域-
Nogo - 66 receptor, ngr, cloned in 2001, is a leucine - rich - repeat glycophosphatidylinositol - anchored membrane protein which mediates nogo - 66 inhibition of axonal outgrowth. both the long acidic amino - terminal domain and the nogo - 66 fragment have strong neurite growth inhibitory activity suggest that nogo - a has at least two inhibitory domains. northern blot, in situ hybridization, western blot and immunocytochemistry analyses show that in addition to oligodendrocytes, nogo - a mrna and nogo - a protein are also expressed in neurons in developing and adult brain and spinal cord, nogo - a is also found in peripheral organs such as heart and testis
Northernblot 、原位雜交、 westernblot和免疫組化結果證明： nogo amrna和nogo蛋白除了在cns的寡突膠質細胞中表達，還表達于發育階段和成年的腦、脊髓和外周神經節的某些神經元中，在外周組織如睪丸和心臟也有表達； nogoe在cns和pns以及多種外周組織中有廣泛分佈； nogo （除表達于腦和心臟外，在骨骼肌中有較高表達。 -
To neutralize the function of cam, the cam binding domain peptide from bovine calcineurin a subunit was chosen because the pre - experiment demonstrated that bovine calcineurin could bind to calmodulin strongely in an acidic and high calcium concentration condition which is similar to the cell wall environment. in order to increase the binding ability of the chimeric secreted calmodulin binding peptide, the plasmid containing two copies of calmodulin binding domain were constructed
它共有26個氨基酸，具有信號肽的典型特徵。為了削弱質外體cam的功能，選擇了牛腦鈣調神經磷酸酶can （ calcineurin ）的a亞基的cam結合域。預實驗結果表明，在近似於胞外環境的酸性高鈣條件下can與cam有強結合。 -
Lfy and lfy - like proteins from angiosperm contain a proline - rich region near the amino terminal and an acidic central region which is typical for transcriptional activators and may be important for the function of lfylike protein. the two domain exists in the variable regions of all lfy - like proteins
與擬南芥leaf 』 y基因相比較，銀杏ginlfy和g毗基因沒有做為轉錄激活區域的位於氨基酸序列中間的酸性區和位於n端的富含脯氨酸區，但這兩個區域均位於leafy基因的非保守區。
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