adhesion protein 中文意思是什麼
adhesion protein
解釋
粘著蛋白，吸附蛋白-
When the approach to get a direct binding molecule was proved not fruitful, attention was turned to find binding sources for the purpose of further isolating the binding protein. the first considered and also the relatively easier - obtained materials are some adhesion molecules. results showed, only n - cam 140 showed ambiguous binding
， idin砰proteina磁珠為結合反應載體，從小鼠成年全腦勻漿作為結合起始材料，以蔗糖密度梯度離心法進4行細胞亞組分分離，以sds page顯示陽性結合條帶，以westernblot確定蛋白身份。 -
Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities
因此將這些蛋白包被、固定到材料表面，觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節，並從以下方面進行探討： （ 1 ）採用不同原代細胞分離方法，研究其對mscs細胞的生物學特性影響。 （ 2 ）檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 （ 3 ）分別採用型膠原及纖維粘連蛋白（ fibronectin ， fn ）包被聚乙醇酸-乳酸共聚物（ poly （ 1actide - co - glycolide ） ， plga ）膜及多孔塊型plga材料，觀察細胞在單層或三維培養狀態下，型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。 -
. . nearly all aspects of cell life are regulated by reversible protein phosphorylation. some examples include metabolic processes, gene regulation, cell cycle control, transport and secretory processes, the organization of the cytoskeleton, and cell adhesion
蛋白可逆磷酸化幾乎可以調節所有的細胞活動，包括代謝過程、基因表達調控、細胞周期調控、運輸和分泌過程、細胞骨架的形成和細胞粘連。 -
There are so many molecules involved the fertility, such as : spl7, a mammalian testis - and sperm - specific protein, can specifically bind with zona pellucida, dextran, dextran sulfated, and fucoidin. another germ cell cyritestin is a testis - and sperm - specific protein belonging to the adam family. it has a disintegrin domain at the n - terminal, known as a integrin ligand, that suggests cyritestin could be involved in sperm adhesion and fusion with the egg membrane previous study demonstration
配子中的許多分子均參與了上述關鍵環節，如在精母細胞、精細胞和睪丸精子中表達，並特異性與卵子透明帶糖蛋白、葡聚糖、糖酐脂結合的精子表面蛋白17 （ sp17 ） ，以及參與識別或與卵子膜上的整合素相互作用的adam家族成員之一的cyritestin蛋白等。
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