agmatine -coumaroyltransferase 中文意思是什麼
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Agmatine inhibits the afferent activity of carotid baroreceptor in rats
胍丁胺抑制大鼠頸動脈竇壓力感受器活動 -
1. hemodynamic effects of agmatine in dahl salt - sensitive hypertensive and dahl salt - resistant rats the hemodynamic effects of agmatine were investigated in anaesthetized dahl salt - sensitive ( ds ) hypertensive and dahl salt - resistant ( dr ) rats. the results are as follows : ( 1 ) agmatine ( 1, 10, 20 mg / kg, iv. )
一、胍丁胺對dahl鹽敏感型高血壓大鼠和dahl鹽抵抗型大鼠血流動力學的影響在麻醉dahl鹽敏感型( ds )高血壓大鼠和dahl鹽抵抗型( dr )正常血壓大鼠,研究了靜注胍丁胺對血流動力學的影響。 -
Taken together, the results indicate that agmatine can dose - dependently decrease hr, map, lvp, + lv dp / dtmax, ci and tpri in ds hypertensive and dr normotensive rats. the hemodynamic effects of agmatine are mediated mainly by irir with the participation of i2 - ir and a2 - ar
以上結果表明,肌丁胺可顯著降低麻醉dr和ds大鼠的hr , map , lvp ,士lvdputmvci和tpri ;此效應似主要由jr所介導,並有iz二r和山ar參與。 -
And agmatine also decreased apa, vmax ) v dd, rpf and apd50, 9o in a concentration - dependent manner in human atrial fibers and guinea pig papillary muscles
胍丁胺還可濃度依賴地縮短離體豚鼠乳頭肌與人心房纖維的動作電位的時程,抑制v _ ( max )和降低vdd和rpf 。 -
Our previous studies demonstrated that agmatine not only reduced the amplitude of action potential ( apa ), maximal rate of depolarization ( vmax ), velocity of diastolic ( phase 4 ) depolarization ( vdd ), and rate of pacemaker firing ( rpf ), but also prolonged 90 % duration of action potential ( apd90 ) in a concentration - dependent manner
我們先前的實驗證明,胍了胺可劑量依賴性地抑制兔竇房結起搏細胞的0相最大上升速度( v _ ( max ) ) ,動作電位幅度( apa )和舒張期除極化速度( vdd ) ,起搏細胞放電頻率( rpf ) ,而且能延長90動作電位時程( apd _ ( 90 ) ) 。 -
( 3 ) yohimbine ( 4 mg / kg ), a selective a2 - ar antagonist, also partially attenuated the effects of agmatine
門)預先靜注瞇哩淋受體門r )和a廠腎上腺素能受體阻斷劑( a廠ar ) idazoxan ( 2 -
The purposes of the present study were to investigate ( 1 ) the hemodynamic effects of agmatine in anaesthetized dahl salt - sensitive ( ds ) hypertensive and dahl salt - resistant ( dr ) rats ; ( 2 ) the effect of agmatine on vascular tension in the isolated aortic artery of rats and the underlying receptor mechanism ; ( 3 ) the effects of local injection of agmatine on femoral, renal, and mesenteric vascular beds by constant flow perfusion method ; ( 4 ) the effect of agmatine on l - type calcium current ( / ca - t ) in rat ventricular myocytes with whole - cell configuration of the patch - clamp technique ; ( 5 ) the effects of agmatine on free intracellular calcium concentration ( ca2 + d of isolated rat ventricular myocytes
( 3 )採用後肢、腎臟和腸系膜動脈在體恆流灌注法,觀察向灌流環路中直接注射胍丁胺的血管效應。 ( 4 )應用全細胞膜片箝技術,觀察胍丁胺對大鼠心室肌細胞l -型鈣通道電流( i _ ( ca - l ) )的影響。 ( 5 )用fluo3 - am負載分離的大鼠心室肌細胞后,由激光共聚焦法測定單個心室肌細胞[ ca ~ ( 2 + ) ] _ i的熒光強度,觀察胍丁胺對分離大鼠心室肌細胞內游離鈣濃度( [ ca ~ ( 2 + ) ] _ i )的影響。 -
Specifically, agmatine at high dose ( 20 mg / kg ) induced a delayed increment of hemodynamic parameters in ds hypertensive rats but not in dr rats. ( 2 ) idazoxan ( 2. 5 mg / kg ), an antagonist for i2 over irimidazoline receptors and oi2 - adrenoceptor receptors ( a2 - ar ), only partially blocked the effects of agmatine ( 10 mg / kg )
需特別提出的是, ds高血壓大鼠在靜注高劑量腑丁胺q0mg從g )后,各項血流動力學指標出現先降低而後升高的現象,這一結果在dr正常血壓大鼠並未出現。 -
Differential responses of regional vascular beds to local injection of agmatine in rats
區域性血管床對局部注射胍丁胺的不同反應 -
Action of agmatine on tension of isolated aortic artery and its receptor mechanism in rats
胍丁胺對離體大鼠主動脈張力的影響及其受體機制 -
However, little is known about cellular mechanism underlying the cardiovascular actions of agmatine
然而,有關胍丁胺心血管作用的細胞機制,至今尚未見報道。 -
It has been known that agmatine was widely distributed in cardiovascular system of mammalian tissues, suggesting that agmatine could act on cardiovascular system
已知心血管系統能合成和貯存胍丁胺,從而提示其可能對心血管系統有作用。 -
In 1994, li et al isolated agmatine from cow brain. like clonidine, agmatine is an endogenous agonist at imidazoline receptors ( ir ) and a noncatecholamine ligand at ( ai - adrenergic receptors ( ( x2 - ar )
胍丁胺( agmatine )是1994年li等從牛腦中分離純化的一種內源性可樂定置換物質( clonidinedisplacingsubstance , cds ) ,它可能作為一種新型的神經遞質或調質。 -
Electrophysiological effects of agmatine on guinea pig papillary muscles in vitro li xiaotao ; he ruirong
胍基丁胺在離體豚鼠乳頭肌的電生理效應 -
( 4 ) efaroxan ( 2f5 mg / kg ), a selective antagonist for ii over i2 - imidazoline receptors and a2 - ar, could completely blocked the effects of agmatine
N )預先靜注瞇哩晰受體門; )禾a 。腎上腺素能受體阻斷劑efaroxan ( 2
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