antigen presentation 中文意思是什麼

antigen presentation 解釋
抗原呈遞
  • antigen : n. 【醫學】抗原。
  • presentation : n 1 贈送，獻禮；授予；授予儀式；〈罕用語〉贈品，禮物。2 提出；呈遞。3 介紹，引見，謁見；〈英國〉...
  1. Covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation including molecular structure and assembly of mhc molecules, the biology of cytokines, leukocyte - endothelial interactions, and the pathogenesis of immunologically mediated diseases

    課程涵蓋免疫系統的細胞和組織，淋巴球的發育過程，抗原受體的結構和功能，抗原反應過程的細胞生物學以及抗原的呈現，其中包括mhc分子的結構與組合，細胞激素的生物學，白血球和內皮組織的互動關系，以及免疫相關疾病的致病機轉。
  2. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  3. It delivers the false ? folding peptides for presentation to proteasomes in normal cells, while in tumor cells it acts as main tumor - resistant antigen, inducing specific immune response. recent research found that grp94 also relates with cell cycles, differentiation and apoptosis

    此外發現它還具有抗原提呈作用，在正常細胞中參與折疊錯誤蛋白到蛋白酶體的提呈；在腫瘤細胞中作為主要的腫瘤排斥抗原，引發針對該腫瘤細胞的特異性免疫反應。
  4. The hla system plays an very important role in antigen identification and presentation, immune response and regulation, and is also one of the key factors that affect the result of organic transplantation and hematopoietic stem cell transplantation

    Hla系統在抗原識別與呈遞、免疫應答與調控等方面起著極其重要的作用，是影響器官移植物長期存活和造血幹細胞移植成敗的關鍵因素之一。
  5. Grp94 functions as molecular chaperones, which are ( poly ) peptide binding proteins that assist in protein folding, assembly and transport. moreover, its role of the transporter for antigen presentation has been discovered

    目前已知grp94的功能主要是作為分子伴侶，在新生肽鏈合成的早期階段，與新生肽鍵形成穩定的復合物，參與蛋白質的折疊、裝配和轉運。
  6. Macrophage is a kind of immune cell as well as accessory cell. it can function as antiinfection, anticancer, immune response and immunoregulation by phagocytosis, antigen presentation, cytokines secretion, lymphocyte activation, reactive oxygen and no production. it ' s an important part of body immune system

    巨噬細胞（ macrophage ）既是免疫細胞，又是輔佐免疫應答細胞，可通過吞噬、抗原呈遞、分泌細胞因子、激活淋巴細胞和產生活性氧、 no等作用而行使抗感染、抗腫瘤、免疫應答和免疫調節作用，是機體免疫系統的重要組成部分。
  7. As c ii ta is a single gene or protein that affects a large family of genes, it represents an ideal target for intervention in the class ii antigen presentation pathway, for immune suppression in transplantation and autoimmumty

    作為影響一個大基因家族的單個基因或蛋白質， c ta是對mhc -類的抗原提呈過程進行干預的理想靶點，可以在自身免疫損傷和移植排異過程中進行免疫抑制干預。
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