c-peptide c 中文意思是什麼
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The fusion protein was bactericidal active against staphylococcus aureus. in present study, we will truncate the none channel - forming do main, then attach the agrd to the pore - forming region ( k544 - i626 ) to construct a new engineered multidqmain protein machine - compact engineered peptide targeting staphylococcus aureus. such engineered peptide was constructed by linking the gene of staphylococcal agrd pheromone with the gene of c - terminal ( 1626 ) of colicin la pore - forming region ( k544 - i626 ) with site - directed mutation
利用點突變方法將金黃色葡萄球菌信息素agrd （ i型， ystcdfim ）的基因引入到大腸菌素fa梭基端1626基因上，並將限制性內切酶sacl酶切位點基因分別引入到大腸菌素fa的p4和k544上，通過酶切、膠回收、連接獲得含大腸菌素ia水性孔道結構域和金黃色葡萄球菌信息素agrd基因的重組質粒。 -
In the secondary structure of peptide, dihedral angles and are the essential factors of c - h bde. each pair of (, ) has unique bde value which varies with the different combination of and
在多肽鏈的二級結構中，二面角中和w是影響c hbde的主要因素，每一對（ p ， w ）對應一個bde值， bde的數值隨中與w的變化而變化。 -
The western blot analysis show that the antiserum induced by the new antigen plus hemocyanin could bind with the 22kd and 55kd proteins, which were existed in the testis tissue protein of mouse, rat and human. 2 ) the purified peptide emulsified in an equal volume of freund ' s adjuvant and immunized the female balb / c mice with 8 - 10 weeks old. the antiserums and the washings of vaginal membrane were detected by elisa, and shown the highest level of the specific antibody igg was 1 : 6000, while the iga was 1 : 300
二、 p3多肽與弗氏佐劑混懸后免疫近交系balb c小鼠后，在血清和陰道粘膜沖洗液中可檢測出特異性lgg 、 lga ，最高效價分別達到1 ： 6000和1 ： 300 ；免疫后的小鼠脾臟淋巴細胞增殖率升高，淋巴細胞培養上清液中分泌的il 4和inf y也升高，且以il 4更明顯。 -
The results show that : four histidine derivatives from c - terminal were synthesized which is based on the forming peptide bonds, and obtained 58 - 73 % of compounds from boc - his ( tos ) - oh
實驗結果表明：採用多肽合成的方法得到了4個組氨酸羧基末端的衍生物，而且產率較高（ 58 73 ） 。 -
Alternation of plasma c - type natriuretic peptide in cerebral infarction
型利鈉肽變化 -
It is most efficient in clearing the peptide bonds on the c-terminal side of such amino acids tyrosine.
它對裂開諸如酪氨酸這類氨基酸的羧基末端的側肽鏈最為有效。 -
To get in vivo evidences that apoplast calmodulin con 1d regulate plant growth and development process, a chimeric secretion form of calmodulin binding peptide, which contains a signal peptide, a calmodulin binding domain and a c - myc epitope was constructed. the chimeric gene was introduced into arabidopsis. it was expected that the overexpression of this chimeric protein could be secreted into cell wall and bound to apoplast calmodulin, which could reduce the apoplast calmoduin concentration to make an apoplast camodulin " antisense " plant. by observing the potential phenotype change of apoplast calmodulin " antisense " plant, the in vivo function of apoplast calmodulin on plant growth and developmental process could be speculated
但這些多是採用生理學手段和藥理學方法而得出的體外（ invitro ）實驗結果，為了取得質外體cam在植物生長發育過程中發揮重要作用的invivo實驗證據，根據動物中的一些研究方法，本實驗設計並構建了帶有信號肽、 cam結合肽（ can小肽） 、 epitope （ c - myc ）融合基因的載體，並將融合基因通過真空滲入法轉入擬南芥，預期過表達的融合蛋白將會被分泌到細胞外並與質外體cam相結合，這樣就會抑制質外體cam的功能，從而可以構建質外體cam的「反義」植株，通過觀察質外體cam 「反義植株」的表型改變，就可以推斷質外體cam在植物生長發育過程中的功能。 -
New york ( reuters health ) sept 07 - a short period of sleep deprivation causes changes in hormonal glucose regulation, with a strong effect on pancreatic islet secretion, a decrease in glucagon levels and a slight reduction in c - peptide levels, according to a small study in the august issue of the journal of clinical endocrinology and metabolism
紐約（路透社健康新聞） 9月7日據《臨床內分泌及代謝》雜志8月刊上的一項小型研究稱，短期的睡眠不足會導致葡萄糖調節激素改變，對胰島素分泌產生強烈影響，降低高血糖素水平，使c -肽水平輕微減少。 -
The generation of endostatin is catalyzed by proteolytic enzymes, that cleave peptide bonds within the protease - sensitive hinge region of the c - terminal domain
特異性蛋白水解酶降解膠原c末端的蛋白酶敏感區，產生內皮抑素。 -
3 immunogenicity of m3m4 loop recombinant peptide antigen of nr1, neuroexcitotoxicity protective effects and their mechanisms study of antiserum against m3m4 ( 1 ) to explore the immunogenicity of m3m4 loop recombinant peptide vaccine, m3m4 recombinant peptide was injected subcutaneously to immunize balb / c mice ( h - 2 ), cd4 / cd8 t lymphocytes subsets, the cytokine levels in serum and the liter of specific humoral response were detected with facs, indirect elisa and elisa separately
，抗血清還可以結合合成膚nps ，證明該表位具有免疫原性和抗原性。收集抗血清用於功能檢測。 （二） m3m4片段抗血清抗興奮毒性損害作用以臺盼藍染色法和原位末端標記（ tun 』 el ）法觀察抗血清對原代培養海馬神經元興奮毒性壞死和凋亡的保護效應。 -
The complete human znf325 cdna sequence is 2697bp and contains a 1389 - bp open reading frame ( orf ) that encodes a 462 amino acid protein with 15 zinc finger c2h2 motifs. the complete human znf359 cdna sequence is 3270bp and contains a 1932 - bp open read ing frame ( orf ) that encodes a 643 amino acid protein with an n - terminal krab domain and 16 c - terminus zinc finger c2h2 motifs. the zfp28 cdna sequence is 4104bp and contains a 2076 - bp open reading frame ( orf ) that encodes an 868 amino acid protein with an n - terminal signal peptide, two krab domains and 14 c - terminal c2h2 zinc finger motifs
Znf325長2697個堿基，含有一個長為1389個堿基的開放閱讀框，編碼一個長為462個氨基酸的蛋白質，它包含15個c2h2型鋅指結構； znf359長3270個堿基，含有一個長為1932個堿基的開放閱讀框，編碼一個長為643個氨基酸的蛋白質，它包含一個n -端krab結構域和16個c -端c2h2型鋅指結構； zfp28長4104個堿基，含有一個長為2076個堿基的開放閱讀框，編碼一個長為868個氨基酸的蛋白質，它包含一個n -端信號肽，兩個krab結構域和14個c -端c2h2型鋅指結構。 -
The zfp28 cdna sequence is 4104 bp and contains a 2076 bp orf that encodes and 868 amino acids protein with an n - terminal signal peptide, two krab domain, and 14 c - termianal c2h2 zinc finger motifs
Zfp28基因長4076個堿基，含8個外顯子，在基因組dna上長18kb 。它編碼的蛋白質全長868個氨基酸，含1個信號肽， 2個krab框和14個c2h2型的鋅指。 -
Specially warning : youd better have a pancreas function test insulin and c - peptide releasing, etc., at least a sugar tolerance test and takes the same test again after a course of treatment so as to compare the effect, observe the range of pancreas function improving and guide you how to take drugs for the next step
特別提醒，您在服用胰衡前最好做項「胰功」試驗胰島素及c肽釋放量。最起碼做一項「糖耐量」試驗。一個療程完后可重復試驗，對比效果，觀察胰功提高幅度並能指導您下步該如何用藥。 -
Recent radioactive scans within 1 week of a c - peptide test
一周內作過放射掃描檢查c肽者。 -
Obesity, which can cause increased c - peptide levels because of the increased production of insulin associated with obesity
肥胖。肥胖可導致c肽水平升高，因為隨肥胖者多胰島素分泌量高。 -
Over the six - month period there was little change in the stimulated c - peptide values of the group, indicating that they may have had retention of endogenous insulin production longer than expected for young children
在6個月期間，組里的受激c -肽值沒有什麼改變，表明他們可以使孩子保持自身胰島素產生的時間超過預期的時間。 -
At 6 months after ahst treatment, the level of c - peptide, a marker that shows the presence of the body ' s own produced insulin, was significantly greater than the pre - treatment values, and did not change at 12 and 24 months
幹細胞移植后6個月， c -肽水平，反映體內自身產生胰島素的標記物，比治療前顯著升高，在12個月和24個月時也沒有改變。 -
Specifically, the researchers examined the effect of sleep deprivation on plasma concentrations of hormones involved in glucose metabolism, including insulin, glucagon, c - peptide, acth and cortisol levels, before and during a hypoglycemic clamp procedure
研究人員特別研究了在低血糖產生之前及低血糖期間，睡眠不足對血漿中與葡萄糖代謝有關的激素濃度的作用，包括胰島素、高血糖素、 c -肽、 acth和皮質醇水平。 -
Part ii screening of tnfa mimotopes from phage display peptide library : based on the results of screening tnfa binding - peptides, we have tried to use neutral tnfa mcab j1d9 as target to screen tnfa mimotopes from c7c phage display peptide library, which may be another form of antagonist for tnfa, and the mimotopes were identified by sandwich elisa. after 3 rounds of screening, we got 9 phage clones identified as positive clones which can bind with mcab j1d9. we also identified the binding between mimotopes and tnf receptor by competitive elisa, and the results showed strongly binding. the amino acid sequence results shown three different sequences : c - rrpaqsg - c - nkhnrki - c and c - rgmsrki - c
在對噬菌體環七肽庫進行三輪親和性篩選后，隨機挑選20個噬菌體克隆， elisa鑒定出9個陽性克隆，經dna測序推出三種氨基酸序列： c - rrpaqsg - c 、 c - nkhnrki - c和c - rgmsrki - c ，其中優勢克隆序列為c - rrpaqsg - c ；鑒定結果顯示陽性克隆能夠與tnf受體結合，並且能夠阻斷tnf與受體的結合，提示篩選得到的環七肽克隆展示肽具有tnf的抗原性及與tnf受體結第一軍醫大學顧士學位論文合的特性，為tnfa表位模擬肽。 -
These phage display peptides may be the tnfa mimotopes. part iii specific c7c tnfa mimotope phage clone as target for screening of tnfa specific binding - peptides from 12mer phage display peptide library : by using the specific c7c tnfa mimotope as target, we developed a novel approach for screening phage peptide library targeting specific phage display peptides. we used c7c tnfa mimotope phage clone lcs - 7 ( c - rrpaqsg - c ) as target to screen 12mer phage peptide library and identify the positive clones by phage elisa
3 、以特異性噬菌體克隆為靶篩選肽庫的研究? ?一種肽庫篩選新方法的建立：為了深入研究細胞因於與配基（受體或抗體）相互作用的關鍵殘基及其空間構象，在上述研究基礎上，我們以tnfa表位模擬肽克隆為靶篩選噬菌體十二肽庫，找尋與之結合的tnfa結合肽噬菌體克隆；並以此拓寬了噬菌體肽庫的應用范圍。
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