calcineurin 中文意思是什麼
calcineurin
解釋
鈣調神經磷酸酶-
Inositol 1, 4, 5 - trisphosphate receptor involved in the activation of calcineurin signaling pathway in myocardium
三磷酸肌醇受體參與心肌鈣調神經磷酸酶信號通路的激活 -
Optimized measurement of calcineurin phosphatase activity in brain extracts
活性測定方法的優化 -
To neutralize the function of cam, the cam binding domain peptide from bovine calcineurin a subunit was chosen because the pre - experiment demonstrated that bovine calcineurin could bind to calmodulin strongely in an acidic and high calcium concentration condition which is similar to the cell wall environment. in order to increase the binding ability of the chimeric secreted calmodulin binding peptide, the plasmid containing two copies of calmodulin binding domain were constructed
它共有26個氨基酸，具有信號肽的典型特徵。為了削弱質外體cam的功能，選擇了牛腦鈣調神經磷酸酶can （ calcineurin ）的a亞基的cam結合域。預實驗結果表明，在近似於胞外環境的酸性高鈣條件下can與cam有強結合。 -
Elevation of intracellular calcium ions may be partly induced by increased influx through sarcolemma l type - calcium channels. intracellular calcium elevation, on one hand, would activate calpain, a calcium - dependent cysteine protease that degrade the myofibrillar proteins and cause muscle atrophy ; on the other hand, result in activation of calcineurin which enhance the activity of mhc i promoter and inhibit a shift of mhc isoforms from slow to fast in soleus
這樣，可能使得萎縮比目魚肌細胞內鈣離子水平升高，細胞內鈣離子靜息濃度的增加一方面激活calpain ，增加收縮蛋白的降解，使肌肉萎縮；草四軍醫大月卜祠成士學位論文另一方面通過激活鈣調神經磷酸酶，增加快型mhc基因的表達，使骨骼肌肌球蛋白重鏈（ mhc ）發生由慢型向快型的轉化。 -
This article reviews published experience to date with steroid and calcineurin minimization in pediatric renal transplantation and discusses the risks and benefits of these approaches
這篇文章綜述了迄今為止已發表的在兒童腎移植中應用類固醇和鈣調磷酸酶最小化的經驗，並討論了這些治療方法的風險和益處。 -
Abstract ： the greatest benefit of immunosuppression minimization for children may lie in improving patient morbidity, by the elimination of the inherent side effects of steroid and calcineurin inhibitors ( cni )
摘要：兒童免疫抑制最小化的最大益處就在於，通過消除類固醇和鈣調磷酸酶（ cni ）的固有副作用來改善患者的死亡率。 -
Randomized, prospective studies of steroid and calcineurin inhibitor minimization and / or avoidance are warranted to clearly confirm the short and long - term safety and efficacy of alternative immunosuppression combinations
類固醇與鈣調磷酸酶抑制劑的最小化和/或避免應用的前瞻性隨機研究，能夠確保明確替代免疫抑制制劑療法的短期和長期的安全性與有效性。 -
Calcineurin inhibitor minimization and addition of mycophenolate mofetil ( mmf ) or sirolimus have shown variable improvements in renal function, though suboptimal efficacy and safety with the currently proposed regimes have limited their application
鈣調磷酸酶抑制劑最小化以及附加麥考酚酸莫酯（ mmf ）或西羅莫司，已經展現出不定的改善腎功能的作用，雖然欠佳的療效和安全性以及當前提出的管理體制限制了它們的應用。 -
Recent findings : primary interest in antibody induction now falls into four major categories : steroid avoidance ; calcineurin inhibitor reduction as a renal sparing protocol ; minimal immunosuppression protocols ( tolerance ) ; and limiting hepatitis c recurrence
最近的發現：抗體誘導的主要益處現在可以分成四類：避免類固醇的使用；減少鈣調磷酸酶抑制劑的劑量，作為一種腎保護性方案；獲得最低限度的免疫抑制方案（耐受） ；限制丙型肝炎復發。 -
Calcineurin inhibitors ( cyclosporine or tacrolimus ) comprised the immunosuppressive therapy in 49 pregnancies ( 94. 2 % )
49次妊娠（ 94 . 2 % ）是在採用包含鈣調神經抑制劑（環孢素或他克莫司）的免疫抑制方案。 -
Study of the alteration of calcineurin activity regulated by cyclosporine a in vital organs of 1k1c renal hypertensive rats
對腎性高血壓大鼠重要臟器鈣調神經磷酸酶活性的調控 -
We report our experience, the largest to date, of sirolimus - induced pneumonitis following lt. between 1999 and 2006, 186 lier transplant patients receied sirolimus - based immunosuppression, after initial therapy with calcineurin inhibitors ( cnis )
我們報道了至今為止在肝移植術后西羅莫司誘發性肺炎方面病例數最多的經驗. 1999年至2006年， 186例患者開始給予鈣調抑制劑，後接受基於西羅莫司的免疫抑制治療
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