calmodulin 中文意思是什麼

calmodulin 解釋
調鈣蛋白
  1. Cell proliferation and ca2 - calmodulin dependent protein kinase activation mediated by ? 1a - and ? 1b - adrenergic receptor in hek293 cells

    65 .張坦陳鳳榮張幼怡。腎上腺素受體的生物進化。
  2. Effect of calmodulin signal system on glycogen synthesis promoted by glimepiride

    鈣調素信號系統在格列美脲促進糖原合成中的作用
  3. Calcium calmodulin dependent protein kinase ii

    鈣鈣調蛋白依賴性蛋白質激酶
  4. Calcium calmodulin dependent protein kinases

    鈣鈣調蛋白依賴性蛋白質激酶
  5. Calcium signaling : calmodulin dependent phosphatase

    鈣信號發送
  6. Abstract : the effects of terbium ion on the conformation of calmodulin and on the interaction between calmodulin and melittin have been studied by the endogenous fluorescent spectrometry of calmodulin and melittin, and the sensitized fluorescent spectrometry of terbium ion, respectively. the results show that terbium ions have a tight binding site in the i and ii metal - binding sites of calmodulin. the conformation of calmodulin induced by terbium ion can bind melittin and transfer the tryptophane residue of melittin to a relatively hydrophobic environment, while the binding of melittin to calmodulin produces effect on the binding orders of terbium ion in camodulin. results from ft - ir spectrometry have revealed that upon binding of lanthanum ion, apo - calmodulin undergoes a conformational change with the increase of - helix content and the decrease of - sheet content. melittin ' s binding to calmodulin has no effect on its conformation induced by the binding of lanthanum ion to calmodulin

    文摘:分別用鈣調蛋白和蜂毒素的內源熒光光譜以及鋱離子的敏化熒光光譜考察了鋱離子對鈣調蛋白構象變化以及對鈣調蛋白與蜂毒素相互作用的影響.結果表明,鋱離子首先結合在鈣調蛋白的第和第位點,鋱離子不影響鈣調蛋白與蜂毒素的相互作用,蜂毒素與鈣調蛋白作用后不影響鋱離子在鈣調蛋白上的鍵合順序.傅里葉變換紅外光譜結果表明三價的鑭離子與鈣調蛋白作用使鈣調蛋白的螺旋結構增加,折疊結構減少,與鈣離子對它的二級結構影響相類似.稀土離子在鈣調蛋白-蜂毒素復合體系中主要與鈣調蛋白作用
  7. To neutralize the function of cam, the cam binding domain peptide from bovine calcineurin a subunit was chosen because the pre - experiment demonstrated that bovine calcineurin could bind to calmodulin strongely in an acidic and high calcium concentration condition which is similar to the cell wall environment. in order to increase the binding ability of the chimeric secreted calmodulin binding peptide, the plasmid containing two copies of calmodulin binding domain were constructed

    它共有26個氨基酸,具有信號肽的典型特徵。為了削弱質外體cam的功能,選擇了牛腦鈣調神經磷酸酶can ( calcineurin )的a亞基的cam結合域。預實驗結果表明,在近似於胞外環境的酸性高鈣條件下can與cam有強結合。
  8. Like calmodulin and troponin c, caltractin contains four potential calcium - binding sites of predicted helix - loop - helix or ef - hand structure. with the development of technology in biology, more and more academicians study questions for discussion by mutating genes in organisms

    中心蛋白的結構類似於鈣調蛋白、肌鈣蛋白c的結構,含有四個ef - hand ( helix - loop - helix )結構,即四個鈣結合位點。
  9. To get in vivo evidences that apoplast calmodulin con 1d regulate plant growth and development process, a chimeric secretion form of calmodulin binding peptide, which contains a signal peptide, a calmodulin binding domain and a c - myc epitope was constructed. the chimeric gene was introduced into arabidopsis. it was expected that the overexpression of this chimeric protein could be secreted into cell wall and bound to apoplast calmodulin, which could reduce the apoplast calmoduin concentration to make an apoplast camodulin " antisense " plant. by observing the potential phenotype change of apoplast calmodulin " antisense " plant, the in vivo function of apoplast calmodulin on plant growth and developmental process could be speculated

    但這些多是採用生理學手段和藥理學方法而得出的體外( invitro )實驗結果,為了取得質外體cam在植物生長發育過程中發揮重要作用的invivo實驗證據,根據動物中的一些研究方法,本實驗設計並構建了帶有信號肽、 cam結合肽( can小肽) 、 epitope ( c - myc )融合基因的載體,並將融合基因通過真空滲入法轉入擬南芥,預期過表達的融合蛋白將會被分泌到細胞外並與質外體cam相結合,這樣就會抑制質外體cam的功能,從而可以構建質外體cam的「反義」植株,通過觀察質外體cam 「反義植株」的表型改變,就可以推斷質外體cam在植物生長發育過程中的功能。
  10. Calmodulin - dependent cyclic nucleotide phophodiesterase was prepared from bovine brain by two - step deae - cellulose column chromatography

    摘要通過兩次離子交換柱層析,從牛腦中制備鈣調素依賴性的環核苷酸磷酸二酯酶。
  11. Ecms associated with pollen tube growth include arabinogalactan proteins, extensin - like glycoproteins, proline - rich proteins, calmodulin, s - glycoproteins, pectins and those that specifically located in the ovary

    與花粉萌發和花粉管生長相關的雌蕊胞外基質種類主要包括阿拉伯半乳糖蛋白、類伸展素糖蛋白、富含脯氨酸糖蛋白、鈣調素、 s -糖蛋白、果膠以及子房的特異性物質等。
  12. An unusual rice calmodulin isoform, oscam61, was first obtained in our lab, which contains an n - terminal cam domain and a c - terminal basic extension with a potential prenylation site. in vitro activity assays confirm oscam61 as a functional calmodulin. using the green fluorescent protein ( gfp ) as a visual marker, we further studied subcellular localization of oscam61 in stably transformed tobacco cells

    利用綠色熒光蛋白( greenfluorescentprotein , gfp )作為標記,研究了oscam61在煙草細胞中的定位, gfp - oscam61融合蛋白(具有開放的異戊烯化修飾位點)定位於細胞質膜和細胞器膜上,而oscam61 - gfp (異戊烯化修飾位點被gfp封閉)定位於細胞核的核質中。
  13. The predicted vfcpkl protein with 493 amino acids contains all the structural characteristics of reported cdpks and there are four domains of a variable domain, a kinase domain, an autoinhibitory domain and a calmodulin - like domain from n - to c - terminal end

    由編碼區推測的vfcpk1的493個氨基酸序列具有已報道的cdpk的所有典型結構特徵,由n端到c端可分為可變區、激酶區、連接區和調節區四個結構域。
  14. This work laid a foundation for elucidating the functions of ecbp21 by means of molecular biology. further studies about ecbp21 may be benefit to elucidating the mechanism of apoplast calmodulin or enriching

    本實驗結果也為利用分子生物學方法研究ecbp21的生物學功能奠定了基礎,並將有助於闡明胞外cam的作用機制及豐富植物質外體多膚的研究。
  15. The results obtained in our laboratory in the past decade years showed, apoplast calmodulin in plant kingdom may regulate a lot of growth and development process of plant, such as accelerating the proliferation of angelica dahurica suspension cells and the proplast cell regeneration, startup the pollen germination of many plants " pollen and accelerating the elongation of the pollen tube, stimulating the redox of corn root " s cell, inducing the expression of light independent rbss gene, and participating in the regulation of the restraining function of al ~ ( 3 + ) to pollen tube germination

    我室多年的研究結果表明,植物質外體cam可能做為多肽第一信使調節著植物體諸多的生長發育過程:如促進白芷懸浮細胞的細胞增殖和原生質體壁再生,啟動並促進多種花粉的萌發和花粉管的伸長,刺激玉米根細胞的氧化還原反應,誘導rbcs基因光不依賴的表達,以及參與調節胞外al ~ ( 3 + )對花粉萌發的抑制效應等。
  16. All the data above suggested that plc signaling pathway was present in lily and arabidopsis pollen and involved in signal transduction of extracelluar calmodulin to regulate the pollen tube growth

    百合花粉plc的克隆及分析為plc存在並參與花粉萌發和生長提供了分子水平的證據,也使胞外cam的信號及傳遞假說開始有分子生物學方面的依據。
  17. It was found that plc activity was stimulated by both exogenous purified calmodulin and heterotrimeric g protein agonist cholera toxin. while, the stimulated effect on plc activity caused by exogenous calmodulin was inhibited by heterotrimeric g protein antagonist pertussis toxin, and plc antagonist u - 73122 inhibited the effect caused by cholera toxin. we also measure the free ca ~ ( 2 + ) level in germinating pollen grains, and found that exogenous purified calmodulin was able to increase the free ca ~ ( 2 + ) level, and their effects on ca ~ ( 2 + ) level were inhibited by u - 73122

    實驗中,利用[ ~ 3h ] pip _ 2和花粉原生質體共同孵育的體系,檢測出了百合花粉細胞具有依賴pip _ 2的plc活性;利用該體系還檢測出外源鈣調素可促進plc的活性,其中10 ~ ( - 9 ) m的鈣調素可使plc的活性提高三倍;異三聚體g蛋白的激活劑ctx可以激活plc的活性,而其抑制劑ptx可明顯抑制plc活性;外源鈣調素的這種作用可以被ptx抑制;而plc抑制劑u - 73122抑制ctx對plc的激活效應。
  18. Intracellular free calcium and calmodulin expression in a brain edema model induced by endotoxin in infant rats

    幼年鼠內毒素性腦水腫模型及腦組織鈣離子和鈣調素表達的研究
  19. In order to study the upstream and downstream components in g protein and calmodulin signal pathways, a yeast two - hybrid system was used to screen interaction partners of these two proteins

    本文利用酵母雙雜交系統分別篩選了與這兩種蛋白相互作用的蛋白質,以進一步研究g蛋白和cam信號轉導途徑中的其它上下游組分。
  20. Ca2 and calmodulin are involved in the expression of heat shock protein gene in arabidopsis

    鈣調素調節擬南芥熱激基因的表達
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