calpain 中文意思是什麼
calpain
解釋
鈣激活中性蛋白酶-
Changes of calpain activity in postmortem meat of pig
豬宰后肌肉中鈣激活蛋白酶活性變化的研究 -
The effect of focal cerebral ischemic preconditioning on the calpain activity in rats
2表達及細胞凋亡的影響 -
Elevation of intracellular calcium ions may be partly induced by increased influx through sarcolemma l type - calcium channels. intracellular calcium elevation, on one hand, would activate calpain, a calcium - dependent cysteine protease that degrade the myofibrillar proteins and cause muscle atrophy ; on the other hand, result in activation of calcineurin which enhance the activity of mhc i promoter and inhibit a shift of mhc isoforms from slow to fast in soleus
這樣，可能使得萎縮比目魚肌細胞內鈣離子水平升高，細胞內鈣離子靜息濃度的增加一方面激活calpain ，增加收縮蛋白的降解，使肌肉萎縮；草四軍醫大月卜祠成士學位論文另一方面通過激活鈣調神經磷酸酶，增加快型mhc基因的表達，使骨骼肌肌球蛋白重鏈（ mhc ）發生由慢型向快型的轉化。
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