candicidin 中文意思是什麼
candicidin
解釋
加地黴素-
Fr - 008 is a strain producing a complex of heptaene macrolide antifungal antibiotics, one of which, previously named fr - 008 was regarded to bis similar to candicidin, but different in sugar moiety
Hplc分析研究表明，它與灰色鏈黴菌imru3570產生的殺假絲菌素是同一種物質，均含有相同的幾種主要組分。 -
The retention tune of each of the three main peaks of the antibiotic fr - 008 is entirety identical to candicidin, except for one peak ( fr - 008d ), which can also be seen as a very weak signal on the hplc profile of candicidin with the same rt
因此可以推測，這兩個菌株在表型上的差別有可能與鏈黴菌fr - 008中的線性質粒有直接的關系，但也不能排除染色體基因之間的差異。 -
Four c - ch3, six aromatic carbons, six carbons of mycosamine were the characteristics of candicidin d, one ketal corresponding to mycosamine and four ketons indicated that no hemiketal formed between c - 15 and c - 19 in fr - g08b or candicidin d. however, such hemiketal was usually thought having been formed
用這個探針，對鏈黴菌fr - 008的基因文庫進行雜交篩選，獲得了3個陽性克隆，經southern雜交分析，發現它們均含有6 . 4kb共同的陽性片斷。 -
The powder was then applied to a silica gel column chromatography charged with 80 % acetone in water and eluted with the same solvent. after concentrating and drying, relatively pure fr - 008 was obtained. hplc assay a comparison between antibiotic fr - 008 and candicidin has been made by studying the hplc separation profiles of antibiotic fr - 008, candicidin and a mixture of both
對鏈黴菌fr - 008和灰色鏈黴菌imru3570的rflp分析發現，它們的染色體具有很高同源性； pfge的比較研究發現，這兩個菌株的明顯區別是鏈黴菌fr - 008攜帶有兩個線性質粒，而在灰色鏈黴菌imru3570中則沒有這兩個線性質粒。 -
So streptomyces sp. fr - 008 is a new strain synthesizing candicidin. nmr studies analysis of the 1h - 1h cosy spectrum allowed us to distinguish some important chemical shifts of the protons in fr - 008b which could be identified as eandicidin d. especially for amino - mycosamine residue, methyl protons and all the protons on the ring could be defined by correlating relation
利用與糖基合成有關的基因str - de作探針對這兩個菌株的總dna進行了southern雜交，從兩個菌株的總dna中均檢測到一段相同大小的陽性片斷，約6 . 4kd （ bamhi + bglii酶切） 。
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