chemokine 中文意思是什麼
chemokine
解釋
趨化因子-
Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4
- arrestin2是趨化因子受體的一種重要的調節蛋白，本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用，反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制， cxcr4介導的趨化作用則被明顯抑制。 -
While the suppression of ( - arrestin2 endogenous expression by antisense or rnai technology considerably attenuated sdf - 1 ( - induced cell migration. expression of ( - arrestin2 also augmented chemokine receptor ccr5 - mediated but not egf receptor - mediated chemotaxis, indicating the specific effect of ( - arrestin2
與此相似，另一種趨化因子受體ccr5介導的趨化作用也受- arrestin2的調控，但egf受體介導的趨化作用則不受- arrestin2的調控，說明- arrestin2的作用有一定的受體特異性。 -
Expression of - chemokine rantes in human testis and epididymis
在人睪丸和附睪中的表達 -
These findings suggest that candesartan has dosage - dependent, anti - inflammatory effects that are mediated by suppression of nf - b actiation and chemokine expression
這些研究表明，坎地沙坦是劑量依賴性、抗炎作用是通過抑制nf - b的活性和趨化因子表達介導的。 -
These findings suggest that candesartan has dosage - dependent, anti - inflammatory effects that are mediated by suppression of nf - b activation and chemokine expression
這些研究表明，坎地沙坦是劑量依賴性、抗炎作用是通過抑制nf - b的活性和趨化因子表達介導的。 -
Involvement of cxcl16 chemokine in immunological liver injury in mice
16趨化因子在小鼠免疫性肝損傷中的作用 -
The pattern of chemokine receptor polymorphism in healthy and hiv positive chinese adults
研究ccr5在愛滋病帶菌者的呈抗原細胞上的表現方式 -
Study on association between several chemokine polymorphisms and systemic lupus erythematosus
幾種趨化性細胞因子及受體基因多態性與系統性紅斑狼瘡的關聯研究 -
T - cell recruitment and function has been demonstrated in the context of cxcr3 chemokine biology
有關t細胞募集和功能已經在關于趨化因子及cxcr3生物學文章中陳述了。 -
The expression of erythrocyte chemokine receptor on peripheral blood red blood cells of patients with psoriasis
紅細胞趨化因子受體在尋常型銀屑病患者外周血紅細胞中的表達及其臨床意義 -
Here we report that growth cones of rat cerebellar axons in culture turned away from a gradient of sdf - 1, a chemokine that attracts migrating leukocytes and cerebellar granule cells via a g protein - coupled receptor ( gpcr )
以前的證據表明， sdf - 1 ，一種經典的chemokine ，能夠吸引白細胞和遷移中的神經元，這種作用是通過g蛋白耦聯受體介導的。利用生長錐轉向分析，我們發現sdf - 1的濃度梯度能夠吸引或排斥培養的小腦顆粒細胞的生長錐。 -
The extracellular 100pl ( ecl1 ) and ecl2 was linked by disulfide bond to maintenanced the stability of the protein secondary structure. in recent years, we showed that ccr5 as a co - receptor could interact with hiv - 1 infect ion. ccr5 was paid closed attention to since it was cloned in 1996. the aim is to - obtain the sequence of first extracillular domain of 3 chemokine receptor 5 ( ccr5 ) n - terminal gene fragment with high level expression in e. coli and to prepare its specific antibody f ( ab ' ) ;, and its detected method
Ccr5具有g蛋白偶聯受體家族（ g - proteincoupledreceptors ， gpcrs ）所特有的7個跨膜區（ transmembrinedomains ， tm ） ，呈螺旋， tm的氨基酸有很高的保守性，膜外第一襻（ extracellularloop1 ， ecl1 ）和ecl2之間有二硫鍵相連，以維持蛋白質二級結構的穩定性。
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