cleavage site 中文意思是什麼

cleavage site 解釋
切割位點
  • cleavage : n. 1. 劈開，劈裂；劈開處。2. 【生物學】卵裂；分裂；【礦物】解理，劈理。
  • site : n 1 地點；位置；地基。2 場所，現場。3 遺址。4 【計算機】網站，站點〈電腦網路用戶的網站地址〉；萬...
  1. Because of the cleavage site of enterokinase and cnbr was designed in the middle of thioredoxin and cmiv, the expressed peptides of the mutation of cmiv could be cuted down from the fusion protein by enterokinase or cnbr

    由於硫氧還蛋白和抗菌肽之間設計了腸激酶（ enterokinase ）切割位點和cnbr切割位點，通過對該表達的融合蛋白的切割，可得到目標抗菌肽cmiv突變體多肽分子。
  2. 2. the sequence of si gene from ibv - lx4 strain was consisted of 1614 bp from initiation codon atg to the possible cleavage site of spike glycoprotein, encoding for a 18 - amino signal - peptide with the n terminus of si protein and a polypeptide of 537 - amino acids. 19 highly conserved, potential glycosylation sites and 17 cysteines residues were characterized with si protein, homology analysis showe that there were gene deletion -

    S1基因：其全序列共1614bp （從起始密碼子atg到s前體蛋白裂解位點） ，編碼537個氨基酸，其氨基端有一編碼18個氨基酸的信號肽序列，第12 13位氨基酸殘基構成了信號肽的切割位點， 14 19位與111 124位氨基酸殘基為s1蛋白的跨膜區域。
  3. The results indicate that the nucleotide sequences and deduced amino acid sequences of all the guangxi isolates in the signal peptides were highly homologous, but lowly homologous with other reference strains. the amino acid composes and arrangement of all guangxi isolates at the cleavage site has the typical pattern of ndv virulent strains, and is identical with the facts in the field cases. all the guangxi isolates are classified into genotype vii of apmv - 1, the same genotype dominated in china and other areas in recent years

    結果發現，廣西分離株之間在信號肚的核旮酸和氨基酸同源性很高，而與其它參考株差異較大；廣西分離株在裂解位點的氨基酸組成和排列均符合強毒株的特徵，並與毒株在臨床上的致病情況相符；根據apmvlf基因第47位第420位核苦酸序列所繪制的系譜樹吵ylogenetictree ）來看，廠西雞和鵝分離株都歸屬于基因型vll 。
  4. This strain ' s virulence was judged by mean death time of chick embryos ( mdt ), intracerebral pathogenicity index in day - old chicks ( icpi ) and intravenous pathogenicity index in 6 - week - old chickens ( ivpi ) and it was found to be the virulent strain. at last, it was tested by the recurrent infection and found that it was the newcastle disease virus ( ndv ), and it was named hbg - 1 strain. in order to find the difference of the cleavage site of this strain with f48e9 and ? 30 strain, a part of the cleavage site of fusion protein gene fragment was amplified by rt - pcr using a primer and sequenced. the sequence analysis showed this strain had low homology with f4ge9 and cso. a phylogenetic tree based on the published sequences of ndv reference strains was constructed and showed the isolated strain hbg - 1 belonged to the genotype w ndv, a novel genotype ndv

    為了進一步探尋分離株與標準株的異同，又採用rt - pcr方法，擴增獲得分離株f _ o裂解位點附近的基因片段，經測序后與國際上已發表的新城疫病毒的核酸序列進行比較，結果表明其與標準株和疫苗株之間的同源性較低，僅為82 86之間。經系統發育進化樹分析后，判定該分離株為新城疫病毒（ ndv ）基因型。運用計算機軟體對其裂解位點處的氨基酸序列進行預測和分析，結果表明該分離株為新城疫病毒強毒株並具有基因型的典型結構特徵。
  5. In this study, the suitable parameters for the introduction of plasmids phz1358 and pset152 into s. nanchangensis ns3226 from e. coli were tested for developing an conjugation system for s. nanchangensis ns3226. a dnd gene cluster, which encodes an unknown modification system for 5 hvidans 1326 and renders its dna susceptible to site - specific double - strand dna cleavage during electrophoresis was conjugated from e. coli into s. nanchangensis ns3226

    將克隆在整合型載體pset152上的變鉛青鏈黴菌1326的dnd基因簇通過接合轉移導入野生型南昌鏈黴菌ns3226中進行異源表達，觀察到接合轉移子的dna獲得了在含fe ~ （ 2 + ）的電泳緩沖液中電泳時降解的表型。
  6. The gene was 1668bp in length, encoding the f protein composed of 553 amino acids. sequence analysis and its secondary structure prediction showed that the f protein had three major hydrophobic regions consisting of about 25 amino acids, six potential glycosylation sites and thirteen cysteines. a sequence region of basic amino acids, rrqrrf, was found at the f, - f2 cleavage site, indicating that f4ge9 was a typical virulent strain

    序列分析和二級結構預測表明， f _ （ 48 ） e _ （ 9 ）株f蛋白含有3個分別由25個氨基酸組成的疏水區，存在6個潛在的糖基化位點， 13個半胱氨酸殘基，裂解位點區域的氨基酸序列為rrqrrf ，說明f _ （ 48 ） e _ 9株是一株典型的強毒株。
  7. Two amino acid substitutions near the vp2 - vp4 cleavage site were identified in the virulent strain jz2000 and might be involved in increased virulence of the virus. phylogenetic analyses indicated that these two strains were most closely related to some european strains but distinct from wibdv and variant strains

    分子系統進化樹分析表明， zj2000株和jd1株與cu - 1 、 p2 、 cef94 、 harbin等毒株的關系最近，而與歐洲、香港、日本的超強毒株和美國的變異株相對較遠。
  8. None of the isolates from mainland china had multiple basic amino acid at ha cleavage site that confer high pathogenicity to some h5 and h7 atvs

    流感病毒的血凝素ha蛋白是流感病毒的主要抗原之一，其抗體能中和流感病毒的感染，是主要的保護性抗體。
  9. This unusual modification causes wild type s. lividans 1326 dna sensitive to site - specific oxidative double - strand cleavage ( dnd phenotype ). preliminary study revealed that such dna modification involves incorporation of sulphur. the entire functional dnd cluster, 8. 3kb in size, including 3 orfs - dnda, dndb and dndc was involved in this dna modification

    野生型變鉛青鏈黴菌具有一種不同於甲基化修飾的新型dna硫修飾系統，使dna在電泳時易遭到氧化雙鏈切割而導致降解（ dnd ， dnadegradation ）表型（ zhouetal . ， 1988 ， 1994 ， 1999 ） 。
  10. A reverse - transcriptase polymerase chain reaction ( rt - pcr ) based technique was developed to detect newcastle disease virus ( ndv ) of different poultry species origin. four oligonucleotide primers, based on the differences of nucleotide sequence at the cleavage site of fusion ( f ) protein gene between virulent and non - virulent strains of apmv - 1, were designed to amplify specific dna fragment from different viruses

    依據apmv - 1融合蛋白（ f ）基因裂解位點的核苷酸序列與其毒力的相關規律，分別設計合成了四條寡核苷酸引物，建立了一個可迅速檢測不同禽源apmv - 1並可鑒定強、弱毒株的逆轉錄酶?聚合酶鏈式反應（ rt - pcr ）技術。
  11. The cleavage site of putative signal peptide was predicted to occur between 28 ( ala ) and 29 ( ala ) thus the putative mature form of the protein composed of 92 amino acids with a molecular weight of 9. 2 kda

    推測的最可能的信號肽切割位點位於第28 （ alal和29 （ alal個氨基酸之間。椎測的成熟肽共有92個氨基酸，分子量9 zkda 。
  12. Moreover, it did n ' t occur the carboxyl cleavage and lysine residual that substitute for the conserved glycine residual is the novel essential site

    進一步分析表明人map1lc3b並沒有發生羧基端的切割反應而且羧基端的賴氨酸代替了保守的甘氨酸成為人map1lc3b發生修飾的活性位點。
  13. A novel dna modification discovered in streptomyces lividans is different from dna methylation. this unusual modification causes wild type s. lividans dna sensitive to site - specific oxidative double - strand cleavage ( dnd phenotype, dna degradation )

    變鉛青鏈黴菌的dna異常修飾系統是一種不同於甲基化修飾的新型修飾系統，它可使變鉛青鏈黴菌dna在電泳時易遭到氧化雙鏈切割（ dnd表型， dnadegradation ） （ zhouetal . ， 1988 ） 。
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