clq 中文意思是什麼
clq
解釋
補體第一成分q亞單位-
By elisa analysis, inhibition of binding of clq with the c ! q receptors on u937 cells and competitive inhibition of binding of clq with aggregated immunoglobulin g b y selected phage clones, and dna sequencing, a number of similar, but not identical, sets of sequences of clq - binding clones were identified. the deduced amino acid sequences of selected 9 peptides are wyegpftlytwp, hwdpfslsayfp, ltqhnspffllp, tsnpfflwypqp, qtpfqlw, npfnwts, spfxlts, fltwldp and fstflyp. they show significant efficiency to inhibit the binding of clq with the clq receptors on u937 cells and / or aggregated immunoglobulin g, which suggest that the selected peptides contain the modeling epitopes of clq receptor to bind the collage - like region or igg to bind the head domain of clq
然後，採用噬菌體肽庫技術，以c1q為釣餌蛋白，從12肽庫和環7肽庫中親和篩選能與c1q結合的噬菌體克隆，經elisa 、 u937細胞配體結合抑制試驗、 aigg競爭抑制試驗及dna測序，獲得了9個具c1q抑制活性克隆的dna序列，其相應的氨基酸序列為： wyegpftlytwp 、 hwdpfslsayfp 、 ltqhnspffllp 、 tsnpfflwypqp 、 qtpfqlw 、 npfnwts 、 spfxlts 、 fltwldp 、 fstflyp ，它們可能模擬c1qr和或igg的c1q結合表位並抑制c1q的活性。 -
Usually, clr is binding to c1inh ( cl inhibitor ). when immune complex ( ic ) binds to clq, c1inh is detached form clr, and then the serine protease is activated, and then the complement classical pathway is activated
在一般情況下， c1r與c1inh （ c1inhibitor ）結合著，而一旦有免疫復合物（ ic ）結合到c1q上時，浙江大學碩士學位論文cllnh的抑制作用即行移除， clr的構象發生改變，具有酶活性，從而啟動補體激活經典途徑。 -
In this study, a novel strategy to inhibit the activation of the complement system has been developed. to get the purified clq as the target molecule for biopanning, the first step of our purification was to isolate the clq from clr2cls2 by affinity chromatography on igg - sepharose 4b column
本研究另闢蹊徑，以補體經典激活途徑始動分子c1q為靶標，採用噬菌體肽庫技術，親和篩選能與c1q結合的噬菌體克隆，研製可抑制補體激活的c1q模擬短肽。 -
On binding to specific carbohydrate structures on the surface of a broad range of microorganisms, mbl can activate complement system through the activation of mbl - associated serine proteases ( masps ) in antibody - and clq - independent way
甘露聚糖結合凝集素（ mannan - bindinglectin ， mbl ）是c型凝集素超級家族中膠凝素家族成員。
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