complement pathway 中文意思是什麼

complement pathway 解釋
補體途徑
  • complement : n 1 補足（物）；補全；互補（成分），補充。2 （必需的）定量，全量；整套，整組；【航海】（船員的）...
  • pathway : 小路，小徑。n. ＝path.
  1. By recognizing and binding to certain carbohydrate moieties on various pathogens, it can promote the killing of microbes either by acting directly as an opsonin or by activating the lectin complement pathway. however, the function of mbl depends on a certain of levels of serum mbl. mbl deficiency and low levels of serum mbl are the basis for a common opsonic deficiency and are associated with recurrent infections and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis

    然而， mbl功能的發揮有賴于其一定的血清濃度， mbl缺乏或血清濃度過低是引起調理吞噬缺損的根本原因，可增加機體對各種病原微生物的易感性而導致機體反復感染，並且與自身免疫性疾病如系統性紅斑狼瘡（ systemiclupuserythematosus ， sle ） 、類風濕性關節炎（ rheumatoidarthritis ， ra ）的發生、發展有關。
  2. An array of regulatory proteins have been found, which inhibit the formation of central enzymes involved in early stages of the complement activation pathway. these include membrane cofactor protein ( mcp cd46 ), decay - accelerating factor protein ( daf cd5 5 ), complement receptor 1 ( cr1, cd35 ), as well as cd59, which inhibits formation of the membrane attack complex during later stages. these regulatory factors are widely expressed and abundant on many cells, and in fluids of reproductive system

    目前發現，機體多種細胞以及生殖系統的體液中表達和分泌豐富的補體調控蛋白，包括作用於補體活化早期階段的cd55 、 cd46 、 cd35和作用於補體活化終末階段的cd59 ，它們分別通過抑制補體活化過程中關鍵的c3 、 c5轉化酶和抑制形成膜攻擊單位，抵抗補體對自身組織細胞的攻擊。
  3. These suggest that the hemolytic activities displayed by amphioxus humoral fluid appear to represent the vertebrate complement system probably operating via the alternative pathway ( ap )

    這些結果說明：文昌魚體液中存在著類似於脊椎動物替代途徑補體樣的溶血活性。
  4. Usually, clr is binding to c1inh ( cl inhibitor ). when immune complex ( ic ) binds to clq, c1inh is detached form clr, and then the serine protease is activated, and then the complement classical pathway is activated

    在一般情況下， c1r與c1inh （ c1inhibitor ）結合著，而一旦有免疫復合物（ ic ）結合到c1q上時，浙江大學碩士學位論文cllnh的抑制作用即行移除， clr的構象發生改變，具有酶活性，從而啟動補體激活經典途徑。
  5. Standard practice for testing for alternative pathway complement activation in serum by solid materials

    通過固體材料測試血清中替換途徑互補活化性的標準實施規程
  6. The presence of complement - like activity in the humoral fluid of amphioxus was examined. the complement classical pathway ( cp ) activity is assayed by determining the amount of serum required to hemolyse a given number of sensitized sheep red blood cells ( srbc ), whereas the complement alternative pathway ( ap ) activity measured in the same manner, but by using rabbit red blood cells ( rarbc ) instead of sensitized srbc

    文昌魚體液可溶解懸浮在10mmol legta - mg - gvb緩沖液中的正常的兔血紅細胞、綿羊紅細胞、及部分哺乳動物、鳥類、兩棲類和魚類的代表動物的血紅細胞；而在gvb ~ （ 2 + ）緩沖液中時對抗體包被的綿羊紅細胞卻沒有溶血活性。
  7. Through different regulation pathway have been developed to inhibit the activation of complement, there is still not a satisfactory way which can make reasonable regulation to the activation of complement

    因此，抗補體治療一直是補體學研究中的重要領域之一。人們先後嘗試過許多抑制補體激活的途徑，但都存在或多或少的問題。
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