cytotoxicity 中文意思是什麼

cytotoxicity 解釋
細胞毒性
  1. Effect of laminaria polysaccharide sulfate on the activation and cytotoxicity of mouse celiac m

    海帶硫酸多糖對小鼠腹腔巨噬細胞激活及細胞毒作用的影響
  2. In vitro cytotoxicity evaluation of comfort denture adhesive

    義齒粘附劑的體外細胞毒性評價
  3. The metabolites eliciting inhibition to foam cell formation process of macrophage produced by endophyte hccb00017 were studied. several products were isolated through solvent extraction, and silica gel chromatography et al. one compound, hccb00017 - a, showed cytotoxicity ; the other two, hccb00017 - c and hccb00017 - e, showed inhibitory activity against foam cell formation process of macrophage

    對具有巨噬細胞泡沫化抑制活性的植物內生菌hccb00017的代謝產物進行研究，應用溶媒萃取、硅膠柱分離等方法，從其發酵液中分離出具有細胞毒性的活性物質hccb00017 - a ，以及具有巨噬細胞泡沫化抑制活性的組分hccb00017 - c和hccb00017 - e 。
  4. Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn

    蓖麻毒素進入細胞的機理不甚明了，一般認為是rtb先與細胞膜受體結合，主要經過受體介導的內吞作用進入吞噬體，然後沿著內體、高爾基體、內質網等逆向分泌途徑，有序地運輸到內質網，最後從內質網轉位進入細胞漿，在胞漿內攻擊核糖體，從而抑制蛋白質的合成，導致細胞死亡。
  5. Mdr1 express product p - glycoprotein was detected by immunocytochemical method and flowcytometry. the cytotoxicity and multidrug resistance reversion effect of tea polyphenol was examined by mtt assay in mcf - 7 and mcf - 7 adr carcinoma cell lines, and compared with pgp inhibitor quinidine. the pgp expression of mcf - 7 adr was strongly positive, the positive rate was 15 % ; the pgp expression of mcf - 7 was negative, the positive rate was 1. 8 %. ic50 of tea polyphenol to mcf - 7 and mcf - 7 adr is 115. 2g ml and 207. 6g ml respectively. ic50 of quinidine to mcf - 7 and mcf - 7 adr is 129. 8mol l 42. 1g ml and 94. 1mol l 30. 5g ml respectively. tea polyphenol and quinidine changed little toxicity of adriamycin to mcf - 7, but tea polyphenol and quinidine improved the sensitivity of mcf - 7adr to adriamycin significantly. immunocytochemistry and flow cytometry can detect p - glycoprotein expression level qualitatively and quantitatively. tea polyphenol is not only an anti - tumor agent, but also a multidrug resistant modulator similar as quinidine. tea polyphenol is advantageous for its little toxicity in tumor treatment

    用免疫組化法和流式細胞儀對腫瘤細胞系mcf - 7和mcf - 7 adr的p -糖蛋白表達水平進行定性定量研究。用噻唑藍比色法mtt研究茶多酚的細胞毒性及其對耐藥性的逆轉作用，並與pgp抑制劑奎尼定進行了比較。免疫組化法檢測p -糖蛋白表達水平， mcf - 7 adr呈強陽性，而mcf - 7呈陰性流式細胞儀定量檢測結果mcf - 7 adr細胞系細胞陽性率為15 % ， mcf - 7細胞系細胞陽性率為1 . 8 % 。
  6. Thermo effects raise the cytotoxicity of chemotherapy drug towards tumor cells. thermo fluid also provide hyperthermia thermotherapy

    .溫熱效應增強化療藥物對腫瘤組織的細胞毒性作用溫熱效應本身具有抗腫瘤作用
  7. Effect of fucoidan - galactosan sulfate from laminaria japonica on the cytotoxicity of murine peritoneal macrophages

    對小鼠巨噬細胞細胞毒活性的影響
  8. We also investigated the pathological changes of mouse liver, thymus and cerebrum cortex challenged by so2 inhalation by in vivo tests. we studied the apoptotic induction on mouse spleen cells and cytotoxicity of human embryo lung fibroblasts of so2 derivatives by in vitro tests. in vivo tests of sulfur dioxide inhalation showed : ( 1 ) effects on mouse lung of so2 challenge : we found no significant apoptotic changes induced by so2 inhalation but obvious pathological changes of lung with vacuolating of osmiophilic multilamellar bodies which maybe related with the decrease of surfacant and decrease of microvillus of type ii alveolar cells ; we also found thickening of part of basement lamina between type i alveolar cells and capillary endothelium cells which may inhibit the dispersion of oxygen and contribute to lung dysfunction

    二氧化硫熏氣染毒的體內實驗結果表明，在本次實驗的濃度范圍內（ 56mg m ~ 3 、 112mg m ~ 3 、 168mg m ~ 3低、中、高三個濃度） ： （ 1 ）通過透射電鏡、 dna凝膠電泳分析和流式細胞分析發現二氧化硫吸入染毒一周對小鼠肺臟沒有明顯的凋亡誘導作用，但通過透射電鏡觀察發現二氧化硫可引起肺臟明顯的超微結構改變，引起型肺泡上皮細胞板層體空泡化，微絨毛減少，線粒體緻密化或腫脹變性；肺泡血管內皮細胞和型肺泡上皮細胞之間基膜增厚，使氧氣彌散功能出現障礙，從而降低肺功能。
  9. Hydroxyapatite poly - l - lactide for cytotoxicity of human bone marrow karyote

    左旋聚乳酸對人骨髓有核細胞毒性的實驗
  10. The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased

    結合以上創建的方法和免疫熒光流式細胞術，用k562細胞株可溶性分泌物（上清）對外周血單個核細胞（ pbmc ）進行培養以模擬體內微環境，然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究，結果發現用腫瘤上清培養的pbmc細胞數量下降明顯，但同時對其有激活作用，且呈劑量依賴性；細胞數的下降主要是由細胞壞死和凋亡引起的，腫瘤上清對細胞周期沒有阻斷作用，反而略有促進作用； t細胞亞群比例增加，並促進表達th1 、 th2細胞因子。
  11. 1, due to the limitation of existing assay for evaluation of cell proliferation and cytotoxicity, in this study we developed a novel method

    基於目前測定免疫細胞增殖殺傷的方法的局限性，本研究首先建立一種用流式細胞儀測定該指標的新方法。
  12. Several polysubstituted biphenyl compounds containing four skeletons were firstsynthesized from ellagic acid via a reduction with dibal - h. the cytotoxicity activities of these compounds were evaluated against human tumor cells in vitro

    以鞣花酸為原料經關鍵的二異丁基氫化鋁還原首次合成了數個擁有4個骨架的多取代聯苯化合物，並對其人類腫瘤細胞毒活性進行了體外測試。
  13. In ivtro cytotoxicity test indicated that the cell toxicity of the cck leaching solution was approximately at 0 level

    體外細胞毒性實驗示浸提液細胞毒性接近於0級。
  14. Biological evaluation of medical devices - part 5 : tests for in vitro cytotoxicity

    醫療器材的生物評價.第5部分:體外細胞毒性試驗
  15. The acellular matrix treated by sds or glutaraldehyde should be cleaned by normal saline, or there will be cytotoxicity in it. the results of cell culture and implantation experiment demonstrate the high degree of cytocompatibibity and biocompatibility of this kind of acelluler matrix

    A半乳糖殘基是豬到人的主要異種抗原，會導致超急性免疫排斥，要實現豬到人的異種移植首先要去除的就是o gal 。
  16. In conclusion, so2 can not only affect respiratory system, but also other organs such as spleen, liver, thymus on their histological structures and every organ performs very differently under so2 exposure. so2 derivatives has cytotoxicity both on mouse spleen cells and human embryo lung fibroblasts

    說明二氧化硫代謝衍生物對人胚肺成纖維細胞和小鼠脾細胞都有一定毒性，並且在一定范圍內對小鼠脾細胞具有一定的凋亡誘導作用。
  17. The security of cp i according to the experiments of mice accute toxicity was evaluated, guinea pig sensitization and cytotoxicity experiment in integer level and cell level. it showed that : the mice had no toxic reaction ; the guinea pig ' s points of injection had no erythema and dropsy ; the cytotoxicity was lower than i class. the results proved that cp i had no poison side effects

    通過小鼠急性毒性試驗、豚鼠致敏試驗、細胞毒性試驗對自製cp進行整體水平和細胞水平的生物安全性評價，觀察期內，小鼠未見異常毒性反應；豚鼠注射點無紅斑及水腫情況；細胞毒性小於級，結果證明本方法制備的cp無毒副作用。
  18. The biological activity of purified lt 27 was tested with the assay system, and its biological activity was 2 - 3 107 iu / mg. pro. the cytotoxicity of purified lt 27 was in the same level with rhtnfp and lt international standard. it shows that lt deletion could keep its high cytotoxicity towards tumour cell l929 in vitro after 27 amino acids deleted from its n - terminal

    用建立的淋巴毒素生物活性測定方法對上述純化的淋巴毒素缺失體lt 27的生物活性進行檢測，測得其比活為2一3xl口iu / mg . proo純化的淋巴毒素缺失體lt 27的生物活性與rhtnfp和淋巴毒素國標標準品的生物活性大致相當，表明lt經n端缺失27個氨基酸后仍能保持很高的體外腫瘤細胞毒活性。
  19. Advances in the study of cytotoxicity of microcystin

    微囊藻毒素的細胞毒性研究進展
  20. Biological evaluation of medical devices - tests for in vitro cytotoxicity

    醫療器械的生物評定.在試管內的細胞毒性試驗
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