dependent protein kinase 中文意思是什麼

dependent protein kinase 解釋
依賴性蛋白激酶
  • dependent : adj. 1. 依靠的,依賴的。2. 從屬的,隸屬的,【語法】從屬的。3. 由…決定的。4. 下垂的,懸吊的。n. 1. 受贍養者,靠人生活的人。2. 扈從,侍從。3. 依存[從屬]物。
  • protein : n. 【化學】朊,蛋白(質)。
  • kinase : n. 【生物化學】激酶。
  1. Cell proliferation and ca2 - calmodulin dependent protein kinase activation mediated by ? 1a - and ? 1b - adrenergic receptor in hek293 cells

    65 .張坦陳鳳榮張幼怡。腎上腺素受體的生物進化。
  2. Protein kinase a is camp - dependent kinase, one of the most important signal transduction pathways, plays a pivotal role in growth, differentiation, tumor occur, cell cycle control, etc. pka activators such as camp, 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes, also in xenopus oocytes

    蛋白激酶a ( proteinkinasea , pka )是依賴于camp的絲蘇氨酸蛋白激酶,是重要的信號傳導途徑之一,廣泛參與許多生命過程,包括生長、分化、腫瘤發生、細胞凋亡、細胞周期調控等。以小鼠卵母細胞為實驗對象,給予pka激動劑camp 、 8 - br - camp或磷酸二酯酶抑制劑imbx ( isomethylbutylxanthine )均可抑制小鼠卵母細胞的胚泡破裂及減數分裂成熟。
  3. Calcium calmodulin dependent protein kinase ii

    鈣鈣調蛋白依賴性蛋白質激酶
  4. The enzyme digest analysis shows that the arm repeats of c - terminal are conceivably conservative domain. in arc1 protein, there are some active sites including n - glycosylation sites, camp - and cgmp - dependent protein kinase phosphorylation sites, protein kinase c phosphorylation sites, casein kinase ii phosphorylation sites, tyrosine kinase phosphorylation sites, n - myristoylation sites, amidation sites and leucine zipper pattern. it probably take part in the signaling process of self - incompatibility

    同時在arc1蛋白質中還發現了拉鏈結構和多個磷酸化位點,包括camp和cgmp依賴的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨酸激酶磷酸化位點、糖基化位點等,拉鏈結構為arc1蛋白之間及與其它蛋白的相互作用提供了可能,而磷酸化位點是arc1參與信號傳導過程所必需的。
  5. Huangyal4 was complete nucleotide sequence of 1 854 bp with a nucleotide orf ( 1575 bp ), which encoded a protein consisting of 524 aa with molecular weight of 62. 2 kda and pi of 8. 96. strongly basic ( + ) amino acids, strongly acidic ( - ) amino acids, hydrophobic amino acids and polar amino acids of the protein were 13. 74 %, 11. 64 %, 36. 45 % and 22. 70 % respectively, and predicted secondary structure of the protein revealed many conserved domains such as n - glycosylation site, protein kinase c phosphorylation site, casein kinase ii phosphorylation site, n - myristoylation site, camp - and cgmp - dependent protein kinase phosphorylation site, tyrosine kinase phosphorylation site and a cytochrome p450 cysteine heme - iron ligand signature which was typical of cytochrome p450. a - helix and b - sheet of the protein is 47. 7 %, 45. 0 % respectively

    Huangya14 )為材料分離克隆到一個細胞色素p450基因,命名為bccyp86mf5 , cdna全長1854bp ,含1575bp的完整開放閱讀框,編碼524個氨基酸,其編碼蛋白質的分子量為61 . 2kda 、等電點為8 . 96 ;堿性氨基酸、酸性氨基酸、疏水氨基酸和極性氨基酸分別占總氨基酸的13 . 74 、 11 . 64 、 36 . 45和22 . 70 ;二級結構預測包括n -糖基化位點、依賴于camp和cgmp的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨基酸激酶磷酸化位點、 n -豆蔻酰化位點和細胞色素p450的典型區域,半胱氨酸亞鐵血紅素配體信號區等, -螺旋和-折疊分別佔47 . 7 、 45 . 0 ;與bccyp86mf1基因的氨基酸序列同源性達到95 . 2 ,與擬南芥cyp86c4的達到85 . 9 。
  6. The vfcpkl has an obvious kinase catalytic domain for ca2 + / calmodulin dependent protein kinases and serine / threonine protein kinases, and a calcium - binding domain like calmodulin

    Vfcpk1具有明顯的ca ~ ( 2 + )鈣調素依賴蛋白激酶及絲氨酸蘇氨酸蛋白激酶的激酶區以及類似於鈣調素的鈣結合區。
  7. Mpf is a complex that consists of the protein kinase p34cdc2 and the regulatory protein cycli b ; the protein kinase activity of p34cdc2 is strictly dependent on its association with cyclinb. in xenopus laevis eggs the absent of cyclin b, mpf will not be activited

    Ca卜活化p34 」擬的機制第一步是結合cycinb ,並且處于磷酸化狀態,即thr14 、 tyrls和tlirl61都處于磷酸化狀態;第二步是cdc25磷酸酶通過是thr14 、 tyr15脫磷酸化而激活p34 」擬。
  8. The protein level of p27 klpl increased at ih, decreased from 6 to 24h after 2gy, it decreased from 3 to 24 h after logy, and the level of p27kipl associated with cdk2 decreased, then lost its inhibition function to cyclin - dependent kinase

    Eycline / enkz的負調控因子p27k , p 』蛋白表達水平在zoy照射后lh略有增加, 6一9h開始下降; 10gy照射后3h開始下降,持續到24h ,可見,隨著ir劑量的加大和處理時間的延長, p27kip 『蛋白表達水平下降的程度加大。
  9. Changes of calcium calmodulin - dependent protein kinase gene expression during differentiation of 3t3 - l1 preadipocyte

    1脂肪細胞誘導分化過程中的表達變化
  10. In this study, we showed that the protein levels of the cyclin - dependent kinase inhibitor p21 rapidly increased in the one - cell staged fertilized eggs treated with pma. the cleavage from one - cell stage of the fertilized eggs into two - cell stage was inhibited

    但研究表明p21結合cdc2的能力不如其他cdks ,其介導的g2 m期的調控是由於p21蛋白抑制cdk2 cyclina復合物的活性,下調cdc25磷酸酶活性,阻止cdc2tyr - 15的去磷酸化,降低mpf活性。
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