deprivation study 中文意思是什麼
deprivation study
解釋
剝奪研究- deprivation : n. 1. 剝奪；（聖職等的）褫奪，免職；廢止。2. 喪失（氧氣、維生素等）。
- study : n 1 用功，勤學；〈常 pl 〉學習；研究 （of）; 研究對象；研究項目；值得研究的問題；學問，學業，學科...
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New york ( reuters health ) sept 07 - a short period of sleep deprivation causes changes in hormonal glucose regulation, with a strong effect on pancreatic islet secretion, a decrease in glucagon levels and a slight reduction in c - peptide levels, according to a small study in the august issue of the journal of clinical endocrinology and metabolism
紐約（路透社健康新聞） 9月7日據《臨床內分泌及代謝》雜志8月刊上的一項小型研究稱，短期的睡眠不足會導致葡萄糖調節激素改變，對胰島素分泌產生強烈影響，降低高血糖素水平，使c -肽水平輕微減少。 -
To make clear the hypothesis, a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study, respectively. we first studied the cellular localization of kvl. 2 and the co - localization of kvl. 2 protein and vegf receptors flk - 1 and flt - 1, observed the effect of mcao on kvl. 2 expression and phosphrylation in the rat brain in vivo, then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl. 2 in sh - sy5y cells. finally, in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl. 2 phosphorylation, we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl. 2 phosphorylation
為了驗證上述假設，本文分別在整體和離體水平，採用大腦中動脈缺血（ middlecerebralarteryocclusion ， mcao ）和體外氧?糖剝奪（ hypoxiaandglucose - deprivation ， hgd ）缺血模型，首先了解了kv1 . 2蛋白的細胞定位及與vegf受體flk - 1和flt - 1的共存情況，觀察了整體mcao后缺血再灌不同時間大鼠腦內kv1 . 2蛋白的磷酸化水平變化，然後通過外源性給予vegf蛋白，在sh - sy5y細胞株上觀察其對缺血細胞存活率及kv1 . 2蛋白磷酸化水平的影響，最後利用vegf反義脫氧寡核苷酸（ oligodeoxynucleotide ， odn ）特異阻斷內源性vegf蛋白的表達，觀察內源性vegf蛋白在缺血細胞損傷及調節kv1 . 2蛋白磷酸化中的作用，以進一步明確vegf缺血保護效應與其調節kv1 . 2蛋白磷酸化之間的關系。
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