effector pathway 中文意思是什麼
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The two single - pass transmembrane proteins, delta and serrate, have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway. rbp - j, the mammalian homolog of su ( h ), recognizes the core sequence ( c / tgtgggaa ) of dna
Rbp - j是果蠅促神經發生基因su （ h ） （ suppressorofhairless ）在哺乳動物的同源物，它通過其識別序列（ c tgtgggaa ）結合於受調控基因的啟動子區，在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。 -
Rbp - j directly interacts with ramic to activate transcription of downstream target genes that prevent cell differentiation. thus, rbp - j is a critical effector molecule in notch signaling pathway
5dpc胚胎和人的hela細胞cdna文庫中篩選到一個可以與rbp - j第四軍醫大學博士學位論文相互作用的新蛋白kyot -
Delta, jagged and serrate have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway
Rbp - j是果蠅促神經發生基因su （ h ） （ suppressorofhairless ）在第四軍醫大學碩士研究生論文哺乳動物的同源物。
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