g protein 中文意思是什麼

g protein 解釋
g蛋白
  • g : 1. generator. 2. German. 3. Germany. 4. giga 十億。5. Gossypium 棉屬。6. grid. 7. Gulf. 8. 【軍事】 gun.
  • protein : n. 【化學】朊,蛋白(質)。
  1. Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4

    - arrestin2是趨化因子受體的一種重要的調節蛋白,本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用,反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制, cxcr4介導的趨化作用則被明顯抑制。
  2. For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development

    如g蛋白偶聯受體通過g蛋白介導產生胞內信使( camp , cgmp , dg , ip _ 3 )將胞外信號傳遞到胞內,從而引起生物學效應;內質網上也存在著一些跨膜蛋白,其中一些與蛋白質的合成及運輸有關,一些與物質代謝有關,如葡萄糖- 6 -磷酸酶。
  3. G protein coupled receptor kinases and arrestinsg

    蛋白偶聯受體激酶和羈留蛋白
  4. Gq protein is a type of heterotrimeric g protein which is made up of, . gq protein which have been discovered recently exist in many invertebrate photoreceptor cells

    Gq蛋白是最近幾年發現的存在於許多無脊椎動物的感光細胞內的一種g蛋白類型,是由、 、三個亞基組成。
  5. Here we report that growth cones of rat cerebellar axons in culture turned away from a gradient of sdf - 1, a chemokine that attracts migrating leukocytes and cerebellar granule cells via a g protein - coupled receptor ( gpcr )

    以前的證據表明, sdf - 1 ,一種經典的chemokine ,能夠吸引白細胞和遷移中的神經元,這種作用是通過g蛋白耦聯受體介導的。利用生長錐轉向分析,我們發現sdf - 1的濃度梯度能夠吸引或排斥培養的小腦顆粒細胞的生長錐。
  6. They are then released from places all over the cells when levels of calcium rise inside the neuron or when certain g - protein - coupled receptors are activated

    只要神經元內部的鈣離子濃度增加,或是某些g蛋白復合受體受到活化,內生性大麻素就可從神經元各處釋放出來。
  7. Mixing lactalbumin with either casein or soy protein in a 20 g protein / 100 g diet formula significantly enhanced the immune response in comparison to that of mice fed diets containing 20 % soy protein or casein

    添加乳白蛋白到酪蛋白及大豆蛋白配方組的免疫反應較未添加者有顯著增強。
  8. Stat proteins are activated by g - protein coupled receptors, while it has not been reported whether cck receptors, a kind of g - protein coupled receptors, can activate jak / stat pathway

    Stat蛋白可被g蛋白偶聯受體激活,而cck受體作為一種g蛋白偶聯受體,是否對jak stat通路具有直接激活作用,尚未見報道。
  9. G - protein - coupled seven - transmembrane receptor

    七次跨膜g蛋白耦聯受體
  10. Our previous work verified that heterotrimeric g protein was involved in regulation of pollen germination, tube growth and in the transmembrane mechanism of extracellular cam signal. in the present study, we provide further evidence that plc signaling pathway was presented in lily pollen and involved in extracellular cam signal transduction mechanism in pollen by molecular, biochemical and physiological approaches. these evidence included : the pip _ ( 2 ) - dependent plc activity was also detected in purified lily pollen protoplasts

    為了給上述信號轉導過程提供進一步的證據,本文以百合花粉為材料,從plc活性的測定、 plc基因的克隆及其與花粉萌發的關系、以及plc活性被g蛋白和cam調控等方面,為肌醇磷脂系統參與花粉萌發和細胞外鈣調素的信號轉導過程進一步提供了分子生物學和生物化學的證據。
  11. In addition, the well retained stability and integrity of cell membrane of boea leaves might also be an important mechanism which make them resurrect well. by using mrna differential display, 5 desiccation sensitive cdnas, 52 desiccation - induced cdnas, 21 up - regulated cdnas, 14 down - regulated cdnas and 16 phosphate induced cdnas were obtained. the cloning, sequencing, homological blasting and northern blotting results of 5 desiccation - induced cdnas and 3 phosphate induced cdnas implied that signal transduction induced by desiccation, regulatory gene cascades and functional genes such as g protein, protein kinase, vp3 - and mad3 - like genes might be involved in dehydration in the resurrection plant boea hygrometrica

    對其中5個脫水特異誘導表達牛耳草光合作廠j的脫水保護和復甦機理的cdna (包括可能與復甦能力有關的cdna )和3個磷酸鹽處理誘導表達的cdna進行克險測序、同源性探測和northern雜交檢測表明,牛耳草脫水過程中誘導表達的基因可能涉及到脫水脅迫的信號轉導「蛋白、蛋白激酶等) 、調節基因的級聯作用( vp3 , mad3樣基因等) 、結構基因產物調節細胞結構(包括細胞質膜)在脫水脅迫中的穩定性等。
  12. It was found that plc activity was stimulated by both exogenous purified calmodulin and heterotrimeric g protein agonist cholera toxin. while, the stimulated effect on plc activity caused by exogenous calmodulin was inhibited by heterotrimeric g protein antagonist pertussis toxin, and plc antagonist u - 73122 inhibited the effect caused by cholera toxin. we also measure the free ca ~ ( 2 + ) level in germinating pollen grains, and found that exogenous purified calmodulin was able to increase the free ca ~ ( 2 + ) level, and their effects on ca ~ ( 2 + ) level were inhibited by u - 73122

    實驗中,利用[ ~ 3h ] pip _ 2和花粉原生質體共同孵育的體系,檢測出了百合花粉細胞具有依賴pip _ 2的plc活性;利用該體系還檢測出外源鈣調素可促進plc的活性,其中10 ~ ( - 9 ) m的鈣調素可使plc的活性提高三倍;異三聚體g蛋白的激活劑ctx可以激活plc的活性,而其抑制劑ptx可明顯抑制plc活性;外源鈣調素的這種作用可以被ptx抑制;而plc抑制劑u - 73122抑制ctx對plc的激活效應。
  13. Hd biosciences co., ltd has announced an important research collaboration with organon, the human health care business of akzo nobel. the agreement relates to the development by hd biosciences of functional assays for a number of identified g - protein coupled receptors and ion channels

    根據這項協議,華大天源將為歐加農公司構建一系列的g蛋白偶聯受體家族和離子通道家族的篩選模型,這些篩選模型均適應于高通量藥物篩選。
  14. In order to study the upstream and downstream components in g protein and calmodulin signal pathways, a yeast two - hybrid system was used to screen interaction partners of these two proteins

    本文利用酵母雙雜交系統分別篩選了與這兩種蛋白相互作用的蛋白質,以進一步研究g蛋白和cam信號轉導途徑中的其它上下游組分。
  15. Recent researches implicate that raplgap may interact with different type of alpha subunit in heterotrimeric g protein and suggest a cellular cross - talk between small g proteins and heterotrimeric g protein

    最近研究發現,某些g亞單位可與rap1gap結合而調節rap1gap的活性或影響異源三聚體g蛋白的信號轉導。
  16. We firstly used g protein a subunit as bait

    首先以g蛋白亞基為誘餌構建了誘餌蛋白表達載體。
  17. Pretreatment with the phospholipase c inhibitor u73122 ( 5 umol / l ) significantly inhibited the il - 2 - induced depression of contraction. conclusion : it is concluded that the effect of il - 2 on contraction of ventricular myocytes is mediated via the cardiac k opioid receptor, and the post - receptor signal transduction pathway includes a ptx sensitive g protein and phospholipase c. 2 effect of interieukin - 2 on intracellular calcium tran

    5 200u ffil )濃度依賴性地降低單個心室肌細胞電刺激誘導的鈣瞬變幅度,使舒張末鈣水平升高; ( 2 ) il 2 ( 200u ml )使咖啡因誘導的肌漿網內貯鈣的釋放降低: ( 3 ) 50偷i熱失活!
  18. Significance of g - protein coupled receptor kinase 2 in heart failure

    蛋白耦聯受體激酶2在心力衰竭中的意義
  19. G - protein coupled receptors

    G蛋白耦合性受
  20. Association study of the regulator of g - protein signaling 4 polymorphisms with schizophrenia

    基因多態性與精神分裂癥的關聯研究
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