gene augmentation 中文意思是什麼
gene augmentation
解釋
基因增強- gene : n. 【生物學】基因。 dominant gene顯性基因。
- augmentation : n. 1. 擴大，增加。2. 增加物。3. 【音樂】增音。4. 【軍事】擴編。5. 【徽章】名譽副徽。
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The newly identified gene, nyd - sp27 has structural similarity to an isoform of phospholipase c. nyd - sp27 was expressed endogenously in human pancreatic - duct cells and upregulated in cystic fibrosis. researchers has proved that suppression of the gene resulted in augmentation of phospholipase - c - coupled calcium - ion release and protein kinase c activity, improvement in the amount of mutated cftr reaching the plasma membrane, and thus restoration of pancreatic anion secretion
Nyd - sp27內源性表達在人體的胰腺導管上皮細胞，並在囊性纖維化時表達增高，顯示該基因可能與病變有關。研究人員發現通過抑制該基因在人體囊性纖維化胰腺導管細胞中的表達，可以糾正缺陷的胰腺陰離子分泌。
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