gene cluster 中文意思是什麼

gene cluster 解釋
基因簇
  • gene : n. 【生物學】基因。 dominant gene顯性基因。
  • cluster : n 1 叢集；叢；（葡萄等的）串，掛；（花）團；（秧）蔸；組。2 （蜂、人等的）叢，群，群集。3 【物理...
  1. In addition to avermectins, s. avermitilis produces oligomycin, a strongly toxic compound. gene deletion vector pxl05 was used to disrupt oligomycin polyketide synthase ( pks ) encoding genes ( olma ) in streptomyces avermitilis cz8 - 73, the producer of anthelmintic avermectins b and the cell growth inhibitor oligomycin. olma gene cluster in the chromosome was displaced by deletion allele on the plasmid via double crossover

    本研究以產阿維菌素b和寡黴素的阿維鏈黴菌cz8 - 73為出發菌株，構建了基因缺失載體pxl05 ，並將其轉入cz8 - 73中，通過缺失載體和染色體之間的同源雙交換，對染色體上長達90kb的寡黴素聚酮合酶（ pks ）基因簇（ olma ）進行了缺失。
  2. Abstract : the risk of cluster headache ( ch ) is associated with the g - allele of the g1246a polymorphism in the hypocretin receptor 2 ( hcrtr2 ) gene

    摘要：叢集性頭痛的危險與食慾素受體2的g1246a等位基因多形性有關。
  3. [ b ] abstract : [ / b ] the risk of cluster headache ( ch ) is associated with the g - allele of the g1246a polymorphism in the hypocretin receptor 2 ( hcrtr2 ) gene

    摘要：叢集性頭痛的危險與食慾素受體2的g1246a等位基因多形性有關。
  4. [ size = 2 ] [ b ] abstract : [ / b ] the risk of cluster headache ( ch ) is associated with the g - allele of the g1246a polymorphism in the hypocretin receptor 2 ( hcrtr2 ) gene

    摘要：叢集性頭痛的危險與食慾素受體2的g1246a等位基因多形性有關。
  5. A four - gene block, a rwo - trna gene cluster and six single trna genes involved in the rearrangement, the second gene rearrangement type of mitochondrial dna reported for any pancrustacea arthropod. comparisons of mitochondrial gene arrangements of decapod suggested that rearrangement of the four gene - block found in eriocheir is informative for high level phylogenetic study of decapod

    發生重排的基因包括一個4基因塊的重排、 1個2基因的trna基因簇的重排和6個單一trna基因的重排，形成泛甲殼類線粒體dna的另一種基因重排類型。
  6. The avermetins are a group of closely related macrocylic lactones with exceedingly high activity against helminths and anthropods. this paper review the biosyntheticpathway of the avermectins and the organization of the biosynthetic gene cluster which many groups have analysed and cloned

    阿維菌素為一種典型的次級代謝產物，生物合成途徑復雜，現在基本上對每一步合成途徑的基因及其所編碼的酶都有所了解。
  7. Analysis of the sequence revealed that adda resembled nifs of nitrogen - fixing bacteria and dnda. the entire add gene cluster showed 78 % identity to dnd gene cluster from s. lividans

    同源性比較揭示add基因簇的adda基因與固氮酶基因nifs高度同源， add與變鉛青鏈黴菌dnd核苷酸的同一性為78 。
  8. In order to facilitate the study of biological function of add gene cluster, e. coli - s. avermitilis intragenus conjugation system was established. in addition, phz2114 for the replacement of the entire add gene cluster and phz2130 for disruption of adda were constructed

    建立了除蟲鏈黴菌的接合轉移系統，並構建了用於置換全部基因簇的基因置換質粒phz2114和adda的基因中斷質粒phz2130 ，為研究除蟲鏈黴菌add基因簇的生物學功能奠定了基礎。
  9. According to the cloned gene cluster, people can use genetical technology to obtain the genetical strains which can produce more potent and non - toxical avermectins and its derivatives

    這使得人們可利用基因工程技術來構建工程菌，增加有效組分的產出和生產新型的阿維菌素。
  10. In this study, the avermectin - producing strain streptomyces avermitilis was studied and the avermectin biosynthesis gene cluster in the genomic dna of streptomyces avermitilis s - 2 was altered by the method of gene engineering. insertion inactivation of aved gene in the cluster by introducing apramycin resistance gene into aved gene resulted in the disappearance of " a " components of avermectins. when avec gene was inactivated by the same way, four " 1 " components were lost and only " 2 " components, the potential precursor of ivermectin, were accumulated

    將該基因簇中的aved基因通過插入外源的安普黴素抗性基因片段使其失活，導致發酵產物中4個a組分（不需要的組分）的消失；將基因簇中的avec基因通過同樣手段，使其失活，導致發酵產物中4個「 1 」組分的消失，而主要積累「 2 」組分（進一步改造可成為伊維菌素的前體b _ 2組分） 。
  11. Streptomyces low copy number plasmid scp2 * is also employed for the cloning and recovery of large dna fragment from streptomyces. as scp2 * can accommodate large dna insertions and is efficiently transmissible among its permissive hosts such as s. lividansbut seemed to be unable to replicates in streptomyces sp. fr - 008, it might be a suitable vector for the cloning of the entire fr - 008 pks gene cluster through gene replacement followed by conjugation with 5

    Scp2 *可以在變鉛青鏈黴菌等許可宿主內復制並在許可宿主間有效轉移，但似乎不能夠在鏈黴菌fr - 008中復制，因此可能適合於在鏈黴菌fr - 008中通過進行基因置換及隨后的鏈黴菌fr - 008和變鉛青鏈黴菌間的接合過程來克隆完整的fr - 008生物合成基因簇。
  12. Importance of five genes presented in xenorhabdus nematophilus bp toxin gene cluster to its insecticidal activity

    品系殺蟲毒素基因簇中各基因與殺蟲活性的關系
  13. A meta - analysis on interleukin - 1 gene cluster polymorphism and genetic susceptibility for ankylosing spondylitis

    1基因多態性的薈萃分析
  14. In this study, the suitable parameters for the introduction of plasmids phz1358 and pset152 into s. nanchangensis ns3226 from e. coli were tested for developing an conjugation system for s. nanchangensis ns3226. a dnd gene cluster, which encodes an unknown modification system for 5 hvidans 1326 and renders its dna susceptible to site - specific double - strand dna cleavage during electrophoresis was conjugated from e. coli into s. nanchangensis ns3226

    將克隆在整合型載體pset152上的變鉛青鏈黴菌1326的dnd基因簇通過接合轉移導入野生型南昌鏈黴菌ns3226中進行異源表達，觀察到接合轉移子的dna獲得了在含fe ~ （ 2 + ）的電泳緩沖液中電泳時降解的表型。
  15. 70kb and 130kb in size respectively. though pks gene cluster for antibiotics fr - 008 was cloned, the genes for amino - mycosamine residue remained unknown. thus, attempt was also made to clone the desired gene ( s ), streptomyces sp

    首先從大量的發酵液中提取分離了鏈黴菌fr - 008產生的抗生素fr - 008 ，並通過大孔樹脂吸附、柱層析等手段進行了初步提純。
  16. The derivatives of phz2104 resulting from the disruption of the three putative orfs respectively by aada can not confer dnd phenotype on zx1. using erase - a - base system, a series of exoiii progressive deletion mutants were prepared for sequencing of add gene cluster

    將add基因簇亞克隆到測序載體pbluescript sk （ + ）上，採用exo缺失突變法得到了66個單向遞減缺失亞克隆，然後對這些克隆進行測序。
  17. The application of scp2 * derivied vectors requires that the physical map of a specific gene cluster is known and scp2 * derivatives are suicidal in the host earring the gene cluster

    在新載體系統phz能1一phz622中，我們不但同向插入了來自於野生型變鉛青鏈黴菌中hau3r基因兩側的1
  18. The restriction map of phzl318 carrying the entire add gene cluster from s. avermitilis nrrl8165 was made. its two subclones phz2104 and phz2105 were introduced into s. lividans mutant zx1

    製作了攜帶完整add基因簇的phz1318的限制內切酶圖譜，根據酶譜進行亞克隆得到phz2104和phz2105 。
  19. The total dna of exoconjugants acquired dna degradation phenotype during electrophoresis, which suggested that the dnd gene cluster was heterologously expressed. the phz1358 was used sucessfully as a vector for gene replacement to identify the biosynthetic pathway genes for nanchangmycin in s. nanchangensis ns3226. however, the gene replacement in another potential pks cluster has not succeeded till now

    將利用phz1358構建的基因置換結構（孫宇暉，未發表）導入南昌鏈黴菌ns3226中進行了基因置換實驗，協助完成了南昌黴素生物合成基因簇的克隆，但對另一潛在pks基因簇的基因置換實驗目前還未能完成。
  20. The chief aim of the present study is trying to extend the applications of yac and scp2 *, which have tremendous cloning capacity, for the above mentioned purpose. streptomyces sp. fr - 008 pks gene cluster ( c

    本文對yac和scp2 *這類承載能力較大的載體系統在克隆fr - 008抗生素合成基因簇方面的利用進行了一系列載體改造和克隆策略方面的初步探索。
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