immune complex mechanism 中文意思是什麼
immune complex mechanism
解釋
免疫復合物機制,免疫復合物機理-
The degradation of i k b and dissociation from nf - k b complex are essential process for activation of nf - k b. there is no report about whether cck - 8 inhibits nf - k b activity through inhibiting lps - induced degradation of i k b. the present study was designed to observe the regulatory effect of cck - 8 on changes of immune functions induced by lps, the receptor mechanism and signal transduction mechanism involving mapk, stat3 and i k b at different levels including in vivo and in vitro, in order to study its immunomodulatory effect on reversing es and its molecular mechanisms
Ikb的降解、並從w兒b復合物上解離是w4b激活的必需過程。 ccks是否通過抑制lps誘導的ikb降解，從而抑制nf幾b激活尚未見報道。本研究在整體、細胞及分子水平，觀察了ccke對lps引起的免疫功能改變的調節作用，研究了其受體機制及mapk 、 stat3和ikb的信號轉導機制，以探討cck七抗es時的免疫調節作用及其分子機制。 -
The reason is the tumor cells escape the immunosurveillance whose mechanism is very complex. in general, the explanation is based on two aspects, one is that the tumor cells can passively escape the host immunosurveillance when the host immnue state is low and another is tumor cells can actively secrete factors to down - regulate immune function. the purpose of this paper is to study the mechanism of immunosuppression by tumor cells using a model rnimicing in vivo microinviroment
腫瘤逃避免疫監視的機制非常復雜，但總體上可從宿主免疫狀態及腫瘤細胞等方面來解釋，在宿主免疫狀態低下時，腫瘤細胞可以被動地逃避免疫監視，但是腫瘤細胞也能主動地釋放一些活性物質，下調免疫殺瘤作用，該作用主要通過兩個途徑，即對免疫細胞功能的調節和免疫細胞數量的調節。
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