immunostimulatory 中文意思是什麼
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Lymphotoxin ( lt ) is a kind of pleiotropic lymphocyte - secreted cytokine which mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. in order to increase the antitumor activity of lymphotoxin and reduce its side effects, the recombinant plasmid pet36b - lt 27 was constructed to express soluble fusion protein cbd - lt 27. the active form of lt 27 could be collected directly with several simple steps by three kind of components on the expressed fusion protein
本研究通過構建表達n端缺失27個氨基酸的淋巴毒素融合蛋白的重組質粒，在大腸桿菌中實現融合蛋白的可溶及分泌表達，同時利用表達載體上的幾種特殊序列經簡單的分離純化步驟直接獲得大量的有生物活性的淋巴毒素缺失體lt 27 ，為尋找一種高抗腫瘤活性、低臨床毒副作用的生物抗癌藥物進行了有效的探索。 -
The direct interplay between tumor cells and immune cells could inhibit the immunostimulatory function of dendritic cells ( dc ). more interestingly, tumor cells or tumor tissue could release inhibitors of lymphocyte activation
已有的報道表明，與腫瘤細胞相互作用可以抑制這些免疫細胞包括樹突狀細胞（ dc ）的免疫激發功能，並且在腫瘤的局部抑制dc細胞的功能，並使其數量減少。 -
In this study, we have constructed a new cea dna vaccine and a plasmid of il - 2 by using genetic - engineering technology, and designed the immunostimulatory dna sequence ( iss ). we hope enhance the quantity of cea and the anti ~ cea by using the various vector, cytokine and iss
本文運用基因工程技術構建了cea的dna疫苗pc工cn ，白細胞介素七的真核表達質粒pci可l 《 ，設計合成了硫代修飾的免疫刺激序列門ss ） ，希望從載體、細胞因子和es方面提高cea的表達和抗ea的產生，從而達到對優a陽性腫瘤免疫防治的目的。
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