l-type calcium current 中文意思是什麼
l-type calcium current
解釋
l型鈣電流-
Effects of low - dose capsaicin on l - type calcium current in guinea pig ventricular myocytes
小劑量辣椒素對豚鼠心室肌細胞l -型鈣電流的影響 -
The purposes of the present study were to investigate ( 1 ) the hemodynamic effects of agmatine in anaesthetized dahl salt - sensitive ( ds ) hypertensive and dahl salt - resistant ( dr ) rats ; ( 2 ) the effect of agmatine on vascular tension in the isolated aortic artery of rats and the underlying receptor mechanism ; ( 3 ) the effects of local injection of agmatine on femoral, renal, and mesenteric vascular beds by constant flow perfusion method ; ( 4 ) the effect of agmatine on l - type calcium current ( / ca - t ) in rat ventricular myocytes with whole - cell configuration of the patch - clamp technique ; ( 5 ) the effects of agmatine on free intracellular calcium concentration ( ca2 + d of isolated rat ventricular myocytes
( 3 )採用後肢、腎臟和腸系膜動脈在體恆流灌注法,觀察向灌流環路中直接注射胍丁胺的血管效應。 ( 4 )應用全細胞膜片箝技術,觀察胍丁胺對大鼠心室肌細胞l -型鈣通道電流( i _ ( ca - l ) )的影響。 ( 5 )用fluo3 - am負載分離的大鼠心室肌細胞后,由激光共聚焦法測定單個心室肌細胞[ ca ~ ( 2 + ) ] _ i的熒光強度,觀察胍丁胺對分離大鼠心室肌細胞內游離鈣濃度( [ ca ~ ( 2 + ) ] _ i )的影響。 -
With holding potential of - - 80 mv depolarization beyond - - 50 mv elicited an inward current, peaked at + l0mv and reversed between + 40 mv and + 60 mv 5 ll m nicardipine, a potent blocker of l - type calcium channel, markedly blocked the " ib
開始出現,峰值在去極化刺激至10 20mv出現,翻轉電位為巧0仍0mv 。 l型鈣通道特異性阻斷劑nicadipine可以明顯抑制ib 。 ,並且iv曲線分佈在應用nicardipine前後無改受。
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