lymphocyte-derived chemotactic factor 中文意思是什麼
lymphocyte-derived chemotactic factor
解釋
淋巴細胞衍生趨化因子- lymphocyte : n. 【醫學】淋巴細胞，淋巴球。lymphocytic adj.
- derived : 導生的
- chemotactic : adj. 【生物學】趨化性的，趨藥性的。
- factor : n 1 〈英國〉經銷人；（代客買賣收取傭金的）經紀人；代理商；代辦人；〈蘇格蘭語〉 土地經管人。2 要素...
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Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4
- arrestin2是趨化因子受體的一種重要的調節蛋白，本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用，反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制， cxcr4介導的趨化作用則被明顯抑制。
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