maturation-promoting factor 中文意思是什麼
maturation-promoting factor
解釋
成熟促進因子- maturation : n. 【醫學】化膿；（果實等的）成熟；（才能等的）圓熟；（化學纖維的）老化。
- factor : n 1 〈英國〉經銷人；（代客買賣收取傭金的）經紀人；代理商；代辦人；〈蘇格蘭語〉 土地經管人。2 要素...
-
Oocyte maturation involves the activation of various signal trans - duction pathways that converge to activate maturation - promoting factor ( mpf ) ; this is a key activity that catalyses entry into m - phase of meiosis i and meiosis ii
在爪蟾卵中有大量未被激活的cdc2 - cyclinb復合物，稱為pre - mpf ， pre - mpf在tyr15位脫磷酸變成活性mpf ，起到這個作用的磷酸酶是cdc25 ， cdc25的活性通過磷酸化和細胞位置進行調控。 -
A critical and central component is likely to be mpf ( m - phase promoting factor, another name is maturation - promoting factor, it was first discovered by masui and marikert in 1971, and then purified from xenopus laevis eggs in 1988
P34 ~ （ cdc2 ）有三個重要調節位點thr14 、 tyr15和thr161分別被其他各種因素調節，當thr161處于磷酸化，而thrl4 、 tyrls處于脫磷酸化時， p34拋才能被激活。 -
Porcine il - 12 ( pil - 12 ), also termed as natural killer cell stimulatory factor ( nksf ) and cytotoxic lymphocyte maturation factor ( clmf ), can induce some cytokines, particularly ifn -, from t and nk cells, as well as enhance the cytotoxic activity of these cells. its most critical role may be to initiate the development of cell - mediated immunity by promoting the differentiation of th1 cells from naive t cells
白細胞介素- 12 （ il - 12 ）又名nk細胞刺激因子（ nksf ）或細胞毒淋巴細胞成熟因子（ clmf ） ，能誘導t細胞和nk細胞產生ifn - ，並增強其細胞毒活性，它的關鍵作用是能誘導th0細胞分化為th1細胞以激發細胞免疫進程。 -
Cd 14 * monocytes or bone marrow derived hematopoietic progenitor cells cultured with granulocyte - macrophage colony - stimulating factor ( gm - csf ) and il - 4 differentiate into efficient apc with morphology and cell surface molecule expression typical of immature dc. it was demonstrated that a variety of factors ( such as lps, tnf - a, il - 1, monocyte - conditioned medium, and cd40 receptor cross - linking ) induce the maturation of immature dc to mature dc that are much more potent in activating t cells by increasing the expression of costimulatory molecules and cytokines, promoting the migration of dc to draining lymph nodes, and down - regulating the capacity of dc to capture and process antigen
在體外，外周血cd14 ~ +單核細胞和cd34 ~ +骨髓造血前體細胞在粒細胞-巨噬細胞集落刺激因子（ granulocyte - macrophagecolony - stimulatingfactor ， gm - csf ）和il - 4的共同作用下可分化為未成熟dc ，未成熟dc具有強大的攝取和處理抗原的能力，但其抗原提呈能力較弱；未成熟dc在炎性細胞因浙江大竿俗士學位論文潛廷平子汐ilq ， yfax病原成分汐lpsx單核細胞條件培養液或cd40l等作用下可分化為成熟dc 。 -
Maturation promoting factor, mpf
成熟促進因子
分享友人