mcao 中文意思是什麼

To make clear the hypothesis, a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study, respectively. we first studied the cellular localization of kvl. 2 and the co - localization of kvl. 2 protein and vegf receptors flk - 1 and flt - 1, observed the effect of mcao on kvl. 2 expression and phosphrylation in the rat brain in vivo, then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl. 2 in sh - sy5y cells. finally, in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl. 2 phosphorylation, we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl. 2 phosphorylation

為了驗證上述假設，本文分別在整體和離體水平，採用大腦中動脈缺血（ middlecerebralarteryocclusion ， mcao ）和體外氧?糖剝奪（ hypoxiaandglucose - deprivation ， hgd ）缺血模型，首先了解了kv1 . 2蛋白的細胞定位及與vegf受體flk - 1和flt - 1的共存情況，觀察了整體mcao后缺血再灌不同時間大鼠腦內kv1 . 2蛋白的磷酸化水平變化，然後通過外源性給予vegf蛋白，在sh - sy5y細胞株上觀察其對缺血細胞存活率及kv1 . 2蛋白磷酸化水平的影響，最後利用vegf反義脫氧寡核苷酸（ oligodeoxynucleotide ， odn ）特異阻斷內源性vegf蛋白的表達，觀察內源性vegf蛋白在缺血細胞損傷及調節kv1 . 2蛋白磷酸化中的作用，以進一步明確vegf缺血保護效應與其調節kv1 . 2蛋白磷酸化之間的關系。

Middle cerebral artery occlusion, mcao

大腦中動脈閉塞

Protective effect of electroacupuncture on cerebral function via ameliorating oxidative stress in mcao rats

大鼠再灌注腦功能損傷的保護

Fig. 3 mcao for 3 hours, pwi showed that the maximun reducing amplitued of time - signal intensity was smaller than that of the left temporal lobe on the right sied, and after reperfusion there was almost identical

Pw顯示左側顳葉的時間一信號強度曲線的最在下降幅度較健側小，恢復血供后兩側基本一致

Heat - shock protein 70 gene expression in brain of mcao rats

大鼠腦中的表達

Experimental study on the mechanism of electroacupuncture preventing acute gastric mucosal lesion in rats mcao model

電針抗大鼠急性胃黏膜損傷機理的實驗研究