molecular binding 中文意思是什麼
molecular binding
解釋
分子鍵-
By evaperation of methol with a little pyridine existing, we abtained the supramolecular structure of resorcinarene binding molecular of water by hydrogen bond. this is a clathrate complexation which possessed a novel three dimention supramolecular structure
本文研究了間杯芳烴同吡啶分子于甲醇中形成的超分子體系，其單晶結構表明，間杯芳烴同吡啶分子通過氫鍵自組裝形成了籠形包合物的超分子結構。 -
The high binding affinity and selectivityin conjunction with the polymers ' physical robustness positions molecular imprinted polymers ( mips ) as candidates for use as preliminary screens in drug discovery
聚合物的高親和力、高選擇性及物理性質穩定特點使得分子印跡聚合物可用於藥物開發中的初篩。 -
Topics include : connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation
主題包括：以統計力學、化學位能、平衡態、協同鍵溶性、溶液中/界面間的巨分子行為及溶解等現象來連接巨觀熱力學性質與微觀分子性質。 -
Recently, some new studies suggest that small cytokine peptide - mimics can function as the agonist or antagonist of cytokine receptor, and these small molecular peptides can be synthesized easily and oral adminstration with high concentration. based on these work, we have tried to set up experiment on tnfa - binding peptides and tnfa mimotopes which may be as leads of tnfa antagonist
近年來的研究發現，小分子細胞因子模擬物具有細胞因子受體激動劑或拮抗劑的作用，且小分子模擬物因容易合成並能夠給予高濃度、可口服等優點使其具有更加廣闊的研發與應用前景。 -
The results of emsa showed the obvious retardant bands, which suggest that some proteins in nuclei can bind to the specific dna sequence of mbd3 gene after lps treatment. 5. the molecular mass of this dna binding protein was assessed between 43. 0 - 66. 2 kd by south - western blot
4 .電泳遷移率改變實驗有明顯的滯后帶形成，表明lps刺激后，肝臟組織的細胞核內有轉錄因子與mbd3基因特異的dna序列結合，參與mbd3基因的誘導表達5 . south一westemblot進一步確定此轉錄因子分子量在43 . 0一「 . 2kd之間。 -
( 2 ) in order to achieve the binding mode, the docking simulations were performed between glutathione ( gsh ) and different isomers of 99mtc - hmpao with the package of autodock. the mechanism of the two molecules recognition and the effect of the stereoisomers on its retention in the brain in terms of the level of molecular and theoretical calculations were also discussed in our work
Dock軟體模擬腦灌注顯像劑」 」 to hmpao的不同的異構體與谷眈甘肽（ gsh ）的對接，擬獲得二者的初步結合模式，從分子水平和理論計算上對二者的識別機制以及」 」 to hmpao的立體構型差異對其滯留效應的影響進行了討論。 -
Grp94 functions as molecular chaperones, which are ( poly ) peptide binding proteins that assist in protein folding, assembly and transport. moreover, its role of the transporter for antigen presentation has been discovered
目前已知grp94的功能主要是作為分子伴侶，在新生肽鏈合成的早期階段，與新生肽鍵形成穩定的復合物，參與蛋白質的折疊、裝配和轉運。 -
Recently an abscisic acid binding protein with high specificity and affinity for aba was purified from epidermis of vicia faba l. in our laboratory, and further characterized using various biochemical techniques, there is evidence to link the protein to the physiological effects of aba in some aspects. the above - mentioned work may result in the molecular cloning the gene encoding aba binding protein
近年來，我室利用親和層析從蠶豆下表皮中分離出一種高親合、高度特異性的aba結合蛋白，並完成了對其生化特性深入分析及部分測序，且在一定程度上揭示了該蛋白與aba的生理功能效應存在著內在的聯系，這為進一步克隆aba結合蛋白基因奠定了堅實的工作基礎。 -
Ngf binding to trka receptors results in receptor dimerization and kinase activation. recent evidence supports that not all extracellular subdomains are responsible for receptor activation. structure based drug design for neurotrophic agonists with small molecular weight relies on knowledge of the interaction of neurotrophin with their receptors
Trka在ngf作用下發生二聚化，使胞內域中酪氨酸激酶區激活，從而使trka中酪氨酸自磷酸化，並進一步激活胞內信號轉導通路，從而實現神經營養信號傳遞。 -
The cdna of subunit b was 1470 nucleotides long coding for 489 amino acids with a conservative atp binding site " 324 - sgsit - 328 " and a predicted molecular mass of 54. 29 kda. amino acid sequence alignment analysis suggested that the v - h + - atpase b subunit of s. salsa had high homology with other reported v - h + - atpase subunit b. the h + - atpase subunit h from s. salsa was a hydrophilic protein with 465 amino acids and a predicted molecular mass of 52. 8 kda, which was encoded by a cdna with 1398 nucleotides in orf. blast analysis indicated that the h + - atpase subunit h from s. salsa had a high amino acid sequence identity with those coming from plants, but had relatively low sequence identity with those coming from other species
鹽地堿蓬液泡膜h ~ + - atpaseb亞基是由1470個核苷酸編碼的長達489個氨基酸的多肽，分子量約54 . 29kda ，存在保守的atp結合序列「 324 - sgsit - 328 」 ，與其他物種來源的v - h ~ + - atpaseb亞基具有較高的氨基酸序列相似性； h亞基為親水多肽，開放閱讀框長達1398 - bp ，編碼465個氨基酸殘基，分子量約52 . 8kda ，與植物來源的液泡膜h ~ + - atpaseh亞基具有較高的氨基酸序列相似性，而與其他物種來源的v - h ~ + - atpaseh亞基同源性較低； c亞基開放閱讀框為495 - bp ，編碼164個氨基酸殘基，分子量約16 . 6kda ，為一跨膜多肽，存在四個可能的跨膜區。 -
Both of them are localized within the endoplasmic reticulum ( er ) and possess atp - binding sites. envidence has shown that grps function as molecular chaperones by assisting in the proper folding and assembly of proteins within the er
同時他們又是分佈在內質網（ endoplasmicreticulumer ）腔內的分子伴侶，具有弱的atp酶活性，與atp結合后可以協助新生蛋白質的轉位、折疊以及寡聚蛋白的組裝。 -
Molecular recognition is utilized to describe the molecular binding process in a specific manner. it ' s well known that the antibody / antigen, receptoraigand and enzyme / substrate are the three molecular recognition models in animate bodies
分子識別是分子間專一性的結合過程，抗體與抗原、受體與配體、酶與底物是人們所熟悉的生物體內的分子識別的三個模型。 -
The recombinant pcr technic was used to introduce a linking peptide klgggg to the site between scfv single chain form of the monoclonal antibody sz - 51 specific for the glycoprotein gmp140 on activated platelet membrane and uk32 low molecular weight form of pro - urokinase, to make the scfv - linker - uk32 chimeric gene. this gene was cloned into the transfer vector pbacpak9, and cotransfected with bacpak6 bsu36i digest into sf 9 cells. the fusion protein was secreted into the medium. in the fifth day after the cotransfection, the supernatant of the medium showed 107 iu ml fibrinolytic activity, higher than 25 iu ml fibrinolytic activity of scfv - uk32. elisa showed that the supernatant had the binding activity to activated platelet. wastern blotting also indicated that the supernatant could bind to the monoclonal antibody of urokinase b chain
為了提高重組導向溶栓分子scfv - uk32的溶纖活性，通過重組pcr方法在編碼scfv與uk32的堿基之間引入編碼klgggg連接肽的堿基序列，並克隆到轉移載體pbacpak9上，通過與線性病毒dna bacpak6 bsu36i digest共轉染到昆蟲細胞sf 9內，進行表達。表達產物分泌到上清中，共轉染后第5d天用纖維平板法測得sf 9細胞上清溶纖活性達到107 iu ml ，比未引入連接肽的scfv - uk32的表達活性25 iu ml高。 -
Sds - page proved that the molecular weight of expressed product of the extracellular part of bt - r3 was about 160kda. western blotting showed that the recombinant protein could specifically bind to bt toxic protein crylab, indicating that the bt - r3 is a receptor protein of crylab. the binding site of bt - r3 with crylab was located in extracellular domains of bt - r3 protein
用大腸桿菌系統表達的bt - r3基因的胞外結構域的分子量約為160kda ， western - blot實驗證實，重組蛋白能有效地結合bt毒蛋白cry1ab ，從而進一步確證了bt - r3是cry1ab的受體基因。 -
The cdna expression library that contains no intron theoretically include all expressed genes and conserve resource genes permanently. lt can be used to find out and clone some genes which can express particular protein with modern molecular biological techniques, such as immunological screening, drug - prob screening, southern et al. lt is very important to study the life nature of plasmodium falciparum in molecular level. with the developments of these studies, the drug - resistant mechanism of the plasmodium falciparum and the genes of some specific medicine binding protein can be made well - known. at the same time, the researches will do good to explain the mechanism of some specific medicines in order to design and screen new anti - malaria drugs
建立cdna表達文庫在一次永久保存基因資源的同時，可以利用功能篩選、免疫學篩選、藥物探針篩選、 southern雜交和大規模序列測定等現代分子生物學技術尋找特異性活性蛋白基因，進而克隆和表達這些基因，對從核酸及蛋白質等分子水平研究瘧原蟲的生命活動規律，對揭示其抗藥性分子機理，搞清某些特效藥物結合蛋白的基因及此類藥物的作用機制，對新型抗瘧藥物的合理設計及篩選都具有極其重要的現實意義。 -
The latter plays a very important role in the study of the mechanism and dynamics of the recognition. it includes the molecular modeling, confirming the binding sites, the calculation of interactions between receptor and ligand, the docking research of the complex, the calculation of dynamic and thermodynamic properties etc. many theoretical calculation methods are involved, such as quantum chemistry, molecular mechanisms, molecular dynamics, monte carlo method and free energy calculation and so on
其中計算機模擬方法是研究分子識別機制及其動態過程的重要途徑，包括底物及受體分子模型的構建、底物及受體相互作用位點的確定、相互作用力的計算、底物及受體分子的對接及其動態過程的研究、體系熱力學及動力學性質的計算等方面內容。 -
Molecular chaperone, which exists in various organisms, is a protein that binding with the other protein ' s unstable conformation to make it be stable
摘要分子伴侶為一類與其他蛋白不穩定構象結合併使之穩定的蛋白質，廣泛分佈於各種生物體內。 -
The fabrication methods such as molecular - beam epitaxy and metal - organic chemical vapor deposition and experimental studies of their properties have been reported, and theoretical studies mainly concentrate on the impurity binding energy varying the size of the wire, the effect of the applied electric field or magnetic field, and photoionization of impurities
在實驗上已經用分子束外延和金屬有機化學汽相淀積等技術對其物理性質進行了廣泛的研究，而理論上的研究主要集中於研究量子線的尺寸對雜質束縛能的影響、外加電場或磁場的作用及雜質的光致電離效應。
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