plasminogen activators 中文意思是什麼
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All the currently used thrombolytic agents are plasminogen activators, which are very efficient in restoring the blood flow. they can convert plasminogen into plasmin and thus degrade fibrin. despite the widespread use of established thrombolytic agents such as streptokinase, t - pa and u - pa, all these agents suffer from a number of inadequacies including resistance to reperfusion, occurrence of coronary reocclusion and bleeding complications
介紹了國內外溶栓劑蛋白質工程方面的新進展，主要涉及了組織型纖溶酶原激活劑t - pa尿激酶型纖溶酶原激活劑u - pa鏈激酶sk葡萄球菌激酶sak dspa及tsv - pa的研究進展。 -
The quest continues for plasminogen activators with higher potency, specific thrombolytic activity, fibrin selectivity and longer half - life time. the recent progress in the protein engineering of plasminogen activators, including t - pa, u - pa, streptokinase, staphylokinase and other novel plasminogen activators, was presented in this article
一些pa突變體及新型溶栓劑，如k2p tnk - pa和star等的臨床實驗結果表明它們在延長體內半壽期增強對血纖維蛋白選擇性和溶栓效率等方面有較大的改進。
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