pleiotropic 中文意思是什麼

pleiotropic 解釋
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  1. S. lividans mutant strains zx1 ( dnd cluster deleted ) and zx64 ( dnda disrupted ) had pleiotropic mutations including low mel expression and poor sporulation. it was speculated that dnda together with its downstream dna ( 2. 5kb ) might be involved in these two phenotypes because dnda together with its downstream dna could restore normal sporulation and mel expression to zx64, while dndb and dndc had no such effect because lai and la2 showed no obvious difference in these two phenotypes from wild type s. lividans 1326

    另外通過比較這幾個突變株及野生型菌株在產孢和黑色素基因（ mel ）表達方面的差異，推測dnda及其下游區域與變鉛青鏈黴菌的產孢和刺激外源黑色素基因的表達有關，而dndb和dndc則與之無關，因為la1和la2在這兩種表型上與野生型菌株無明顯差異。
  2. Lymphotoxin ( lt ) is a kind of pleiotropic lymphocyte - secreted cytokine which mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. in order to increase the antitumor activity of lymphotoxin and reduce its side effects, the recombinant plasmid pet36b - lt 27 was constructed to express soluble fusion protein cbd - lt 27. the active form of lt 27 could be collected directly with several simple steps by three kind of components on the expressed fusion protein

    本研究通過構建表達n端缺失27個氨基酸的淋巴毒素融合蛋白的重組質粒，在大腸桿菌中實現融合蛋白的可溶及分泌表達，同時利用表達載體上的幾種特殊序列經簡單的分離純化步驟直接獲得大量的有生物活性的淋巴毒素缺失體lt 27 ，為尋找一種高抗腫瘤活性、低臨床毒副作用的生物抗癌藥物進行了有效的探索。
  3. Proteomic analysis of 042bma - km was carried out using two - dimensional gel electrophoresis. deletion of noea had a pleiotropic effect on protein synthesis levels

    對042bma - km進行的蛋白質組初步分析發現， noea基因的敲除對蛋白質合成水平具有多效性影響。
  4. The two genes were subcloned into pet30 vector, and recombinant proteins with predicted molecular weight were achieved. in this paper, we constructed the recombinant e. coli highly expressing pil - 10 in order to study the pleiotropic immunological regulations in various diseases

    然後將p35基因和p40基因分別亞克隆到原核表達載體pet30c 、 pet30b中，用iptg誘導培養，分別表達出了預期分子量大小的重組蛋白。
  5. Interferon - is an antiviral cytokine produced by activated t cell and nk cell. it upregulated mhc ii antigen expression, influenced the cellular and humoral immune response and has pleiotropic regulatory effects on immune system. one gene was amplified by reverse transcription - polymerase chain reaction ( rt - pcr ) in splenocytes which was stimulated with cona for 24 hours

    -干擾素（ interferon - ， ifn - ）主要由活化的t細胞及nk細胞產生，具有抗病毒作用，也具有上調mhc （ majorhistocompatibilitycomplex ， mhc ）類抗原分子的表達等作用，是影響機體細胞免疫和體液免疫反應的一類具有多種調節效應的細胞因子。
  6. It possess high homology with those of ck2 ( casein kinase 2 ) a subunits from various species. it is now well established that protein kinase ck2 is a pleiotropic and abiquitous serine or threonine kinase, which is highly conserved during evolution. we obtained the complete cdna sequence of ck2 a via 5 " race

    酪蛋白激酶ck2是目前發現的普遍存在於真核生物中的絲氨酸蘇氨酸型蛋白激酶，進化上具有高度的保守性並參與了多種生理功能的調控，因而克隆它的基因具有重要意義。
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