protein domains 中文意思是什麼

protein domains 解釋
功能結構域
  1. Nogo - 66 receptor, ngr, cloned in 2001, is a leucine - rich - repeat glycophosphatidylinositol - anchored membrane protein which mediates nogo - 66 inhibition of axonal outgrowth. both the long acidic amino - terminal domain and the nogo - 66 fragment have strong neurite growth inhibitory activity suggest that nogo - a has at least two inhibitory domains. northern blot, in situ hybridization, western blot and immunocytochemistry analyses show that in addition to oligodendrocytes, nogo - a mrna and nogo - a protein are also expressed in neurons in developing and adult brain and spinal cord, nogo - a is also found in peripheral organs such as heart and testis

    Northernblot 、原位雜交、 westernblot和免疫組化結果證明: nogo amrna和nogo蛋白除了在cns的寡突膠質細胞中表達,還表達于發育階段和成年的腦、脊髓和外周神經節的某些神經元中,在外周組織如睪丸和心臟也有表達; nogoe在cns和pns以及多種外周組織中有廣泛分佈; nogo (除表達于腦和心臟外,在骨骼肌中有較高表達。
  2. In addition, it was also found that this protein shares limited but significant homology with the sam - dependent methyltransferase of mesorhizobium sp. bnc1 ( 32 % similarity ), and the similarity of its 303 - 362 region to the 160 - 220 domains of l11 methyltransferases of e. coli ( prma ) is 41 %. it is suggested that methylation of l11 resulted in effects of noea on nodulation of 042bm

    發現noea與中慢生根瘤菌( mesorhizobiumsp . ) bnc1可能的sam -依賴性的甲基轉移酶相似性為32 ,而其303 - 362區域與大腸桿菌( escherichiacoli )的核糖體50s亞基的l11蛋白甲基轉移酶( prma )的160 - 220結構域的相似性達到41 。
  3. The predicted secondary structure of the protein displays multiple putative transmembrane domains

    1 。計算機軟體分析表明,其編碼的蛋白具有多次跨膜樣結構域。
  4. These three proteins contain two common clif domains, ubox and arm repeats. ubox is putative domain of dimeration of arc1 protein or the binding domain of next element

    這種ubox結構均位於氨基酸序列的中間區域,這個區域有可能是蛋白質發生二聚化的區域或下一級組分的結合的位點。
  5. By the analysis of blastn ( nucleitide level ) and blastp ( amino acid level ), some conversed domains in each protein sequence were dete cted, such as pas domain, pac domain and fhue

    對這4個片段進行核苷酸序列和蛋白序列的同源性比對,發現它們與一些功能保守的結構域具有同源性。
  6. The full - length cdna of ttom1, 1280 bp in length, encodes a deduced 288 a. a. protein with 7 - pass explasmic domains

    Ttom1全長cdna有1280個堿基對,編碼288個氨基酸,有7個跨膜區,是個典型的跨膜蛋白。
  7. The protein encoded by orf1 show strong homology with cation efflux family protein from geobacter sulfurreducens pca [ identities = 65 / 272 ( 23 % ) ], and contains mmt1 - like putative conserved domains kog1485, mmt1 contains conserved domains kog1485 is mitochondrial fe2 + transporter ( cation diffusion facilitator superfamily ). so it can be considered that the protein encoded by o rf1 is fe2 + transporter involved in magnetosome biosynthesis in magnetospirillum gryphiswaldense msr - 1

    經同源比較和保守性結構域分析,推測orf1編碼的蛋白具有fe ~ ( 2 + )轉運功能,在磁小體合成過程中將細胞質中fe ~ ( 2 + )轉運到磁小體囊泡中,合成磁小體的同時去除fe ~ ( 2 + )對細胞的毒害作用。
  8. And the intron had a lot of gt repeated sequence. the dna and protein sequence of this gene was analyzed using the bioinformatics tools. two functional domains were found in the protein

    運用生物信息學手段對3一磷酸甘油脫氫酶基因核酸以及蛋白質序列做出了分析,發現這個基因編碼兩種功能的結構域,磷酸化酶結構域和3一磷酸甘油脫氫酶結構域。
  9. The predicted vfcpkl protein with 493 amino acids contains all the structural characteristics of reported cdpks and there are four domains of a variable domain, a kinase domain, an autoinhibitory domain and a calmodulin - like domain from n - to c - terminal end

    由編碼區推測的vfcpk1的493個氨基酸序列具有已報道的cdpk的所有典型結構特徵,由n端到c端可分為可變區、激酶區、連接區和調節區四個結構域。
  10. It is possible that only the cadherin repeated domain 4, 5, 6 of bt - r3 protein is not enough for bt - r3 protein to bind bt toxic protein, or there is another bind site outside these domains

    這可能是因為光有這些結構域對結合活性來說是不夠的,還需要其它結構域協同。也有可能bt - r3受體蛋白和bt毒蛋白另有其結合位點。
  11. Hydrophobicity analysis suggested that the v - h + - atpase subunit c from 5. salsa was a transmembrane protein with four transmembrane domains. earlier experiments indicated the conserve glutamyl residue in the fourth transmembrane domains might participate in the proton translocating across the membranes

    鹽地堿蓬液泡膜h ~ + - atpasec亞基第四個跨膜區存在高度保守的谷氨酸殘基,先前的研究表明此谷氨酸殘基可能與h ~ +跨脂雙層運輸有關。
  12. Huangyal4 was complete nucleotide sequence of 1 854 bp with a nucleotide orf ( 1575 bp ), which encoded a protein consisting of 524 aa with molecular weight of 62. 2 kda and pi of 8. 96. strongly basic ( + ) amino acids, strongly acidic ( - ) amino acids, hydrophobic amino acids and polar amino acids of the protein were 13. 74 %, 11. 64 %, 36. 45 % and 22. 70 % respectively, and predicted secondary structure of the protein revealed many conserved domains such as n - glycosylation site, protein kinase c phosphorylation site, casein kinase ii phosphorylation site, n - myristoylation site, camp - and cgmp - dependent protein kinase phosphorylation site, tyrosine kinase phosphorylation site and a cytochrome p450 cysteine heme - iron ligand signature which was typical of cytochrome p450. a - helix and b - sheet of the protein is 47. 7 %, 45. 0 % respectively

    Huangya14 )為材料分離克隆到一個細胞色素p450基因,命名為bccyp86mf5 , cdna全長1854bp ,含1575bp的完整開放閱讀框,編碼524個氨基酸,其編碼蛋白質的分子量為61 . 2kda 、等電點為8 . 96 ;堿性氨基酸、酸性氨基酸、疏水氨基酸和極性氨基酸分別占總氨基酸的13 . 74 、 11 . 64 、 36 . 45和22 . 70 ;二級結構預測包括n -糖基化位點、依賴于camp和cgmp的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨基酸激酶磷酸化位點、 n -豆蔻酰化位點和細胞色素p450的典型區域,半胱氨酸亞鐵血紅素配體信號區等, -螺旋和-折疊分別佔47 . 7 、 45 . 0 ;與bccyp86mf1基因的氨基酸序列同源性達到95 . 2 ,與擬南芥cyp86c4的達到85 . 9 。
  13. To further enhance protein productivity of expression vectors, two artificial transcription activating domains, ah and vp2, were linked to cl represser protein of phage through a soft linker, respectively, and thus two artificial transcription activators were created

    為了進一步提高表達載體表達外源蛋白的能力,我們把兩個人工轉錄激活結構域ah和vp2分別通過一個柔性的linker融合到噬菌體ci蛋白的c末端,構建了兩個人工轉錄激活因子。
  14. The complete human znf325 cdna sequence is 2697bp and contains a 1389 - bp open reading frame ( orf ) that encodes a 462 amino acid protein with 15 zinc finger c2h2 motifs. the complete human znf359 cdna sequence is 3270bp and contains a 1932 - bp open read ing frame ( orf ) that encodes a 643 amino acid protein with an n - terminal krab domain and 16 c - terminus zinc finger c2h2 motifs. the zfp28 cdna sequence is 4104bp and contains a 2076 - bp open reading frame ( orf ) that encodes an 868 amino acid protein with an n - terminal signal peptide, two krab domains and 14 c - terminal c2h2 zinc finger motifs

    Znf325長2697個堿基,含有一個長為1389個堿基的開放閱讀框,編碼一個長為462個氨基酸的蛋白質,它包含15個c2h2型鋅指結構; znf359長3270個堿基,含有一個長為1932個堿基的開放閱讀框,編碼一個長為643個氨基酸的蛋白質,它包含一個n -端krab結構域和16個c -端c2h2型鋅指結構; zfp28長4104個堿基,含有一個長為2076個堿基的開放閱讀框,編碼一個長為868個氨基酸的蛋白質,它包含一個n -端信號肽,兩個krab結構域和14個c -端c2h2型鋅指結構。
  15. Sequence variation analysis exhibits high transition to transversion substitution ratios, and transitions and transversions are unsaturated in the sequence of cytochorme b gene. the base composition of the cytochrome b sequences was highly biased. using a structural model of the cytochrome b protein as a template, we divided cyt b sequence data for species within anserifomes into three functional domains

    3 )序列具有較高的轉換顛換比,基因序列中的轉換與顛換都未飽和,序列中的堿基組成高度偏倚: 4 )按照細胞色素為蛋白結構模型,細胞色素b基因全序列可分為三個功能區,堿基替換飽和狀況與不同功能區相關聯。
  16. At present, there is not much study with respect to the functional analysis of testin gene. what we know about is that testin may be a cancer supressing gene. the protein contains three lim domains at c - terminus

    目前對testin基因的功能研究還不多,其蛋白c端含有3個lim結構域,可能是一個抑癌基因。
  17. Hydrophobicity and transmembrane domain analysis show that the protein encoded by orf1 contains five hydrophobic domains and four transmembrane domains. it maybe a transmembrane protein

    經疏水性和跨膜區分析, orf1編碼的蛋白含有5個疏水區、 4個跨膜區,應為跨膜蛋白。
  18. Other domains of the extracellular part of bt - r3 protein are 11 cadherin repeated domains, which mainly consist of p stands that are linked by loop structure, turn residues and random coil

    其餘的胞外區域形成以折疊為主的11個鈣粘蛋白重復結構域。這些d折疊又由loop結構、轉角和無規捲曲連結在一起。
  19. The cadherin repeated domains of bt - r3 protein share high homology with the cadherin domains from african clawed frog ( xenopus laevis ) and e - cadherin ( epithelial ) from mouse ( mus musculus ). so, the 3rd structure of the cadherin repeated domains of bt - r3 protein should be similar to these domains

    Bt - r3受體蛋白的鈣粘蛋白結構域分別與非洲爪蟾( xenopuslaevis )的鈣粘蛋白胞外結構域和小鼠( musmusculus )的上皮鈣粘蛋白胞外結構域有很高的同源性。
  20. The term protein kinase c ( pkc ) stands for a group of at least twelve serine / threconine kinases that are characterized by a high degree of similarity in their catalytic kinase domains and cysteine - rich regions

    前言蛋白激酶c ( pkc )是一組絲蘇氨酸蛋白激酶,參與多種信號傳導系統。包括細胞分化、生長調控、腫瘤發生和細胞凋亡。
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